Results 11 to 20 of about 654,596 (326)
The mechanics of plant morphogenesis
Science, 2023 Understanding the mechanism by which patterned gene activity leads to mechanical deformation of cells and tissues to create complex forms is a major challenge for developmental biology.
E. Coen, D. Cosgrove
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Nature Protocols, 2022 Human intestinal morphogenesis establishes 3D epithelial microarchitecture and spatially organized crypt–villus characteristics. This unique structure is necessary to maintain intestinal homeostasis by protecting the stem cell niche in the basal crypt ...
Woojung Shin, Hyun Jung Kim
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Actin-based force generation and cell adhesion in tissue morphogenesis.
Current Biology, 2021 The generation of organismal form - morphogenesis - arises from forces produced at the cellular level. In animal cells, much of this force is produced by the actin cytoskeleton.
D. N. Clarke, Adam C. Martin
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Nature Communications, 2021 Leigh syndrome (LS) is a severe manifestation of mitochondrial disease in children and is currently incurable. The lack of effective models hampers our understanding of the mechanisms underlying the neuronal pathology of LS. Using patient-derived induced
G. Inak +32 more
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Morphogenesis and cytopathic effect of SARS-CoV-2 infection in human airway epithelial cells
Nature Communications, 2020 SARS-CoV-2, a β-coronavirus, has rapidly spread across the world, highlighting its high transmissibility, but the underlying morphogenesis and pathogenesis remain poorly understood.
N. Zhu +18 more
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Cold Spring Harbor Perspectives in Biology, 2016 Throughout biology, function is intimately linked with form. Across scales ranging from subcellular to multiorganismal, the identity and organization of a biological structure's subunits dictate its properties. The field of molecular morphogenesis has traditionally been concerned with describing these links, decoding the molecular mechanisms that give ...
Brian P, Teague +2 more
openaire +2 more sources
Microorganisms, 2021 Dengue virus (DENV) infection by one of the four serotypes (DENV-1 to 4) may result in a wide spectrum of clinical manifestations, with unpredictable evolution and organ involvement.
Fernanda Cunha Jácome +10 more
doaj +1 more source
Epithelial organization and cyst lumen expansion require efficient Sec13-Sec31-driven secretion [PDF]
, 2012 Epithelial morphogenesis is directed by interactions with the underlying extracellular matrix. Secretion of collagen and other matrix components requires efficient coat complex II (COPII) vesicle formation at the endoplasmic reticulum. Here, we show that
Hodgson, Lorna +3 more
core +2 more sources
Budding epithelial morphogenesis driven by cell-matrix versus cell-cell adhesion.
Cell, 2021 Many embryonic organs undergo epithelial morphogenesis to form tree-like hierarchical structures. However, it remains unclear what drives the budding and branching of stratified epithelia, such as in the embryonic salivary gland and pancreas.
Shaohe Wang +4 more
semanticscholar +1 more source
eLife, 2020 Bacterial shape is physically determined by the peptidoglycan cell wall. The cell-wall-synthesis machinery responsible for rod shape in Escherichia coli is the processive 'Rod complex'.
Gizem Özbaykal +8 more
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