Results 31 to 40 of about 454,146 (304)

Marcksl1 modulates endothelial cell mechanoresponse to haemodynamic forces to control blood vessel shape and size

open access: yesNature Communications, 2020
During lumen formation in blood vessels, endothelial cells become exposed to hemodynamic forces that induce membrane blebbing and changes in cell shape.
Igor Kondrychyn   +9 more
doaj   +1 more source

EmDeplo morphogenesis

open access: yes, 2023
These thesis will argue about the importance of Dynamic Parametric Architecture versus Static Parametric Architecture. Describing the architectonical and the algorithmic context within which the Emergency Deployable System emerged, it will be discussed the importance of adaptability as the missing concept of parametric architecture.
openaire   +4 more sources

Synthetic Morphogenesis [PDF]

open access: yesCold Spring Harbor Perspectives in Biology, 2016
Throughout biology, function is intimately linked with form. Across scales ranging from subcellular to multiorganismal, the identity and organization of a biological structure's subunits dictate its properties. The field of molecular morphogenesis has traditionally been concerned with describing these links, decoding the molecular mechanisms that give ...
Brian P, Teague   +2 more
openaire   +2 more sources

Pericytes regulate VEGF-induced endothelial sprouting through VEGFR1

open access: yesNature Communications, 2017
Pericytes are essential for the development, maintenance and function of vascular networks. Here, Eilken and colleagues show that expression of the decoy receptor VEGFR1 by pericytes spatially restricts VEGF signalling, thus regulating VEGF-induced ...
Hanna M. Eilken   +8 more
doaj   +1 more source

Thyroid hormone receptor knockout prevents the loss of Xenopus tail regeneration capacity at metamorphic climax

open access: yesCell & Bioscience, 2023
Background Animal regeneration is the natural process of replacing or restoring damaged or missing cells, tissues, organs, and even entire body to full function. Studies in mammals have revealed that many organs lose regenerative ability soon after birth
Shouhong Wang   +7 more
doaj   +1 more source

Brazilian Dengue Virus Type 2-Associated Renal Involvement in a Murine Model: Outcomes after Infection by Two Lineages of the Asian/American Genotype

open access: yesPathogens, 2021
Dengue virus type 2 (DENV-2) is, traditionally, the most studied serotype due to its association with explosive outbreaks and severe cases. In Brazil, almost 20 years after the first introduction in the 1990s, a new lineage (Lineage II) of the DENV-2 ...
Fernanda Cunha Jácome   +9 more
doaj   +1 more source

Flow Dynamics and HSPC Homing in Bone Marrow Microvessels

open access: yesCell Reports, 2017
Measurements of flow velocities at the level of individual arterial vessels and sinusoidal capillaries are crucial for understanding the dynamics of hematopoietic stem and progenitor cell homing in the bone marrow vasculature.
M. Gabriele Bixel   +6 more
doaj   +1 more source

Scribbled Optimizes BMP Signaling through its Receptor Internalization to the Rab5 Endosome and Promote Robust Epithelial Morphogenesis [PDF]

open access: yes, 2016
Epithelial cells are characterized by apical-basal polarity. Intrinsic factors underlying apical-basal polarity are crucial for tissue homeostasis and have often been identified to be tumor suppressors. Patterning and differentiation of epithelia are key
Osamu Shimmi   +8 more
core   +2 more sources

FGFR2 is essential for salivary gland duct homeostasis and MAPK-dependent seromucous acinar cell differentiation

open access: yesNature Communications, 2023
Exocrine acinar cells in salivary glands (SG) are critical for oral health and loss of functional acinar cells is a major clinical challenge. Fibroblast growth factor receptors (FGFR) are essential for early development of multiple organs, including SG ...
Marit H. Aure   +6 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

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