Results 21 to 30 of about 459,719 (297)

A method to generate the surface cell layer of the 3D virtual shoot apex from apical initials

Plant Methods, 2017
Background The development of cell pattern in the surface cell layer of the shoot apex can be investigated in vivo by use of a time-lapse confocal images, showing naked meristem in 3D in successive times. However, how this layer is originated from apical
Krzysztof Kucypera, Marcin Lipowczan, Anna Piekarska-Stachowiak, Jerzy Nakielski   +3 more
doaj   +1 more source

Neurotrophin signaling is a central mechanism of salivary dysfunction after irradiation that disrupts myoepithelial cells

npj Regenerative Medicine, 2023
The mechanisms that prevent regeneration of irradiated (IR) salivary glands remain elusive. Bulk RNAseq of IR versus non-IR human salivary glands showed that neurotrophin signaling is highly disrupted post-radiation.
Alejandro M. Chibly, Vaishali N. Patel, Marit H. Aure, Mary C. Pasquale, NIDCD/NIDCR Genomics and Computational Biology Core, Gemma E. Martin, Mousa Ghannam, Julianne Andrade, Noah G. Denegre, Colleen Simpson, David P. Goldstein, Fei-Fei Liu, Isabelle M. A. Lombaert, Matthew P. Hoffman   +13 more
doaj   +1 more source

Picornavirus Morphogenesis [PDF]

Microbiology and Molecular Biology Reviews, 2014
SUMMARY The Picornaviridae represent a large family of small plus-strand RNA viruses that cause a bewildering array of important human and animal diseases. Morphogenesis is the least-understood step in the life cycle of these viruses, and this process is difficult to study because encapsidation is tightly ...
Ping, Jiang, Ying, Liu, Hsin-Chieh, Ma, Aniko V, Paul, Eckard, Wimmer   +4 more
openaire   +2 more sources

Morphological Aspects and Viremia Analysis of BALB/c Murine Model Experimentally Infected with Dengue Virus Serotype 4

Viruses, 2021
Ever since its brief introduction in the Brazilian territory in 1981, dengue virus serotype 4 (DENV-4) remained absent from the national epidemiological scenario for almost 25 years. The emergence of DENV-4 in 2010 resulted in epidemics in most Brazilian
Arthur da Costa Rasinhas, Fernanda Cunha Jácome, Gabriela Cardoso Caldas, Ana Luisa Teixeira de Almeida, Marcos Alexandre Nunes da Silva, Daniel Dias Coutinho de Souza, Amanda Carlos Paulino, Derick Mendes Bandeira, Raphael Leonardo, Priscila Conrado Guerra Nunes, Ronaldo Mohana-Borges, Ortrud Monika Barth, Flavia Barreto dos Santos, Debora Ferreira Barreto Vieira   +13 more
doaj   +1 more source

Loss of the transcription factor RBPJ induces disease-promoting properties in brain pericytes

Nature Communications, 2019
Pericytes are perivascular cells essential for blood-brain barrier maintenance. Here Diéguez-Hurtado et al. show that depletion of the transcription factor RBPJ in pericytes affects their molecular identity and disturbs endothelial cell behaviour ...
Rodrigo Diéguez-Hurtado, Katsuhiro Kato, Benedetto Daniele Giaimo, Melina Nieminen-Kelhä, Hendrik Arf, Francesca Ferrante, Marek Bartkuhn, Tobias Zimmermann, M. Gabriele Bixel, Hanna M. Eilken, Susanne Adams, Tilman Borggrefe, Peter Vajkoczy, Ralf H. Adams   +13 more
doaj   +1 more source

Induction of osteogenesis by bone-targeted Notch activation

eLife, 2022
Declining bone mass is associated with aging and osteoporosis, a disease characterized by progressive weakening of the skeleton and increased fracture incidence.
Cong Xu, Van Vuong Dinh, Kai Kruse, Hyun-Woo Jeong, Emma C Watson, Susanne Adams, Frank Berkenfeld, Martin Stehling, Seyed Javad Rasouli, Rui Fan, Rui Chen, Ivan Bedzhov, Qi Chen, Katsuhiro Kato, Mara E Pitulescu, Ralf H Adams   +15 more
doaj   +1 more source

Accumulation of muscle ankyrin repeat protein transcript reveals local activation of primary myotube endcompartments during muscle morphogenesis [PDF]

, 1997
The characteristic shapes and positions of each individual body muscle are established during the process of muscle morphogenesis in response to patterning information from the surrounding mesenchyme. Throughout muscle morphogenesis, primary myotubes are
Arber, S., Baumeister, A., Pico Caroni, Caroni, P., Anja Baumeister, Silvia Arber, Arber S, Caroni P, Baumeister A   +8 more
core   +1 more source

Single-cell transcriptomics reveals functionally specialized vascular endothelium in brain

eLife, 2022
The blood-brain barrier (BBB) limits the entry of leukocytes and potentially harmful substances from the circulation into the central nervous system (CNS). While BBB defects are a hallmark of many neurological disorders, the cellular heterogeneity at the
Hyun-Woo Jeong, Rodrigo Diéguez-Hurtado, Hendrik Arf, Jian Song, Hongryeol Park, Kai Kruse, Lydia Sorokin, Ralf H Adams   +7 more
doaj   +1 more source

Scribbled Optimizes BMP Signaling through its Receptor Internalization to the Rab5 Endosome and Promote Robust Epithelial Morphogenesis [PDF]

, 2016
Epithelial cells are characterized by apical-basal polarity. Intrinsic factors underlying apical-basal polarity are crucial for tissue homeostasis and have often been identified to be tumor suppressors. Patterning and differentiation of epithelia are key
Osamu Shimmi, Jinghua Gui (3332586), Yunxian Huang, Gui, Jinghua, Jinghua Gui, Yunxian Huang (3332589), Huang, Yunxian, Shimmi, Osamu, Osamu Shimmi (393124)   +8 more
core   +2 more sources

A feed-forward loop coupling extracellular BMP transport and morphogenesis in Drosophila wing [PDF]

, 2012
A variety of extracellular factors regulate morphogenesis during development. However, coordination between extracellular signaling and dynamic morphogenesis is largely unexplored. We address the fundamental question by studying posterior crossvein (PCV)
Osamu Shimmi, Matsuda, Shinya, Jorge Blanco, Blanco, Jorge, Shinya Matsuda, Shinya Matsuda (393123), Shimmi, Osamu, Jorge Blanco (52828), Osamu Shimmi (393124)   +8 more
core   +2 more sources