Results 41 to 50 of about 654,596 (326)

Marcksl1 modulates endothelial cell mechanoresponse to haemodynamic forces to control blood vessel shape and size

open access: yesNature Communications, 2020
During lumen formation in blood vessels, endothelial cells become exposed to hemodynamic forces that induce membrane blebbing and changes in cell shape.
Igor Kondrychyn   +9 more
doaj   +1 more source

Thyroid hormone receptor knockout prevents the loss of Xenopus tail regeneration capacity at metamorphic climax

open access: yesCell & Bioscience, 2023
Background Animal regeneration is the natural process of replacing or restoring damaged or missing cells, tissues, organs, and even entire body to full function. Studies in mammals have revealed that many organs lose regenerative ability soon after birth
Shouhong Wang   +7 more
doaj   +1 more source

Dynamic Image-Based Modelling of Kidney Branching Morphogenesis

open access: yes, 2013
Kidney branching morphogenesis has been studied extensively, but the mechanism that defines the branch points is still elusive. Here we obtained a 2D movie of kidney branching morphogenesis in culture to test different models of branching morphogenesis ...
A. Gierer   +21 more
core   +1 more source

Pericytes regulate VEGF-induced endothelial sprouting through VEGFR1

open access: yesNature Communications, 2017
Pericytes are essential for the development, maintenance and function of vascular networks. Here, Eilken and colleagues show that expression of the decoy receptor VEGFR1 by pericytes spatially restricts VEGF signalling, thus regulating VEGF-induced ...
Hanna M. Eilken   +8 more
doaj   +1 more source

Brazilian Dengue Virus Type 2-Associated Renal Involvement in a Murine Model: Outcomes after Infection by Two Lineages of the Asian/American Genotype

open access: yesPathogens, 2021
Dengue virus type 2 (DENV-2) is, traditionally, the most studied serotype due to its association with explosive outbreaks and severe cases. In Brazil, almost 20 years after the first introduction in the 1990s, a new lineage (Lineage II) of the DENV-2 ...
Fernanda Cunha Jácome   +9 more
doaj   +1 more source

Protease signaling regulates apical cell extrusion, cell contacts, and proliferation in epithelia. [PDF]

open access: yes, 2018
Mechanisms that sense and regulate epithelial morphogenesis, integrity, and homeostasis are incompletely understood. Protease-activated receptor 2 (Par2), the Par2-activating membrane-tethered protease matriptase, and its inhibitor, hepatocyte activator ...
Balouch, Eaman   +8 more
core   +1 more source

Long-range mechanical force in colony branching and tumor invasion [PDF]

open access: yes, 2011
The most concerned factors for cancer prognosis are tumor invasion and metastasis. The patterns of tumor invasion can be characterized as random infiltration to surrounding extracellular matrix (ECM) or formation of long-range path for collective ...
Guo, Chin-Lin   +4 more
core   +1 more source

Imaging morphogenesis [PDF]

open access: yesPhilosophical Transactions of the Royal Society B: Biological Sciences, 2017
The hostile environment of the microscope stage poses numerous challenges to successful imaging of morphogenesis in live tissues. This review aims to highlight some of the main practical considerations to take into account when embarking on a project to image cell behaviour in the context of cells' normal surroundings.
openaire   +2 more sources

Molecular mechanisms underlying phytochrome-controlled morphogenesis in plants

open access: yesNature Communications, 2019
Phytochromes are bilin-binding photosensory receptors which control development over a broad range of environmental conditions and throughout the whole plant life cycle.
Martina Legris   +2 more
semanticscholar   +1 more source

Flow Dynamics and HSPC Homing in Bone Marrow Microvessels

open access: yesCell Reports, 2017
Measurements of flow velocities at the level of individual arterial vessels and sinusoidal capillaries are crucial for understanding the dynamics of hematopoietic stem and progenitor cell homing in the bone marrow vasculature.
M. Gabriele Bixel   +6 more
doaj   +1 more source

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