Results 41 to 50 of about 454,146 (304)

Moving Domain Computational Fluid Dynamics to Interface with an Embryonic Model of Cardiac Morphogenesis [PDF]

, 2013
Peristaltic contraction of the embryonic heart tube produces time- and spatial-varying wall shear stress (WSS) and pressure gradients (∇P) across the atrioventricular (AV) canal.
Marsden, Alison L., Alison L. Marsden (449920), Marsden, Alison L, Cao, Hung, Kung Ethan, Ching-Ling Lien (19909), Lee, J, Hsiai, TK, Yury Miller, Ching-Ling Lien, Kung, Ethan, Hsiai, Tzung K, Mahdi Esmaily Moghadam, Beebe, Tyler, Hsiai Tzung K., Ethan Kung, Chi, Neil C., Lien, CL, Roman, BL, Roman, Beth L, Tyler Beebe, Xu, Xiaolei, Juhyun Lee, Chi Neil C., Chi, NC, Tzung K Hsiai, Marsden, AL, Roman, Beth L., Moghadam, Esmaily, Marsden Alison L., Chi, Neil C, Lien, Ching-Ling, Hung Cao, Hsiai, Tzung K., Miller Yury, Neil C. Chi (449919), Cao Hung, Roman Beth L., Moghadam Mahdi Esmaily, Beebe, T, Miller, Yury, Lee Juhyun, Beth L. Roman (138860), Cao, H, Juhyun Lee (449913), Moghadam, Mahdi Esmaily, Yury Miller (449918), Lien Ching-Ling, Tyler Beebe (449917), Hung Cao (449916), Beth L Roman, Ethan Kung (449915), Mahdi Esmaily Moghadam (449914), Beebe Tyler, Moghadam, ME, Neil C Chi, Lee, Juhyun, Alison L Marsden, Kung, E, Miller, Y, Tzung K. Hsiai (449921)   +60 more
core   +2 more sources

Longitudinal growth of the Saccharina kelp embryo depends on actin filaments that control the formation of a corset-like structure composed of alginate

Scientific Reports
The initiation of embryogenesis in the kelp Saccharina latissima is accompanied by significant anisotropy in cell shape. Using monoclonal antibodies, we show that this anisotropy coincides with a spatio-temporal pattern of accumulation of alginates in ...
Samuel Boscq, Ioannis Theodorou, Roman Milstein, Aude Le Bail, Sabine Chenivesse, Bernard Billoud, Bénédicte Charrier   +6 more
doaj   +1 more source

Thyroid hormone receptor beta is critical for intestinal remodeling during Xenopus tropicalis metamorphosis

Cell & Bioscience, 2020
Background Thyroid hormone (T3) is critical for development in all vertebrates. The mechanism underlying T3 effect has been difficult to study due to the uterus-enclosed nature of mammalian embryos.
Yuki Shibata, Yuta Tanizaki, Yun-Bo Shi
doaj   +1 more source

EpCAM in morphogenesis

Frontiers in Bioscience, 2008
Embryonic development is one of the most complex biological phenomena that involves the appropriate expression and synchronized interactions of a plethora of proteins, including cell adhesion molecules (CAMs). Many members of the diverse family of CAMs have been shown to be critically involved in the correct execution of embryonic development.
Trzpis, Monika, Bremer, Edwin, McLaughlin, Pamela M. J., de Leij, Lou F. M. H., Harmsen, Martin C.   +4 more
openaire   +3 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Coupling between dynamic 3D tissue architecture and BMP morphogen signaling during Drosophila wing morphogenesis. [PDF]

, 2019
At the level of organ formation, tissue morphogenesis drives developmental processes in animals, often involving the rearrangement of two-dimensional (2D) structures into more complex three-dimensional (3D) tissues.
Nix, Stephanie, Gui, Jinghua, Kikushima, Kenji, Kracklauer, Martin, Ishimoto, Yukitaka, Huang, Yunxian, Toddie-Moore, Daniel John, Shimmi, Osamu   +7 more
core   +2 more sources

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

A feed-forward loop coupling extracellular BMP transport and morphogenesis in Drosophila wing [PDF]

, 2012
A variety of extracellular factors regulate morphogenesis during development. However, coordination between extracellular signaling and dynamic morphogenesis is largely unexplored. We address the fundamental question by studying posterior crossvein (PCV)
Osamu Shimmi, Matsuda, Shinya, Jorge Blanco, Blanco, Jorge, Shinya Matsuda, Shinya Matsuda (393123), Shimmi, Osamu, Jorge Blanco (52828), Osamu Shimmi (393124)   +8 more
core   +2 more sources

The Study on Sea Buckthorn (Genus Hippophae L.) Fruit Reveals Cell Division and Cell Expansion to Promote Morphogenesis

, 2023
Due to its unique flavor and high antioxidant content, the sea buckthorn (genus Hippophae L.) fruit is increasingly favored by consumers. Developing from the perianth tube, the sea buckthorn fruit varies greatly among species in both size and shape ...
Jing Zhao, Hongdan Zhou, Kun Sun, Zhihua Zhang, Zengfu Bai   +4 more
core   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source