Results 61 to 70 of about 654,596 (326)

Chemotactic Collapse and Mesenchymal Morphogenesis

open access: yes, 2004
We study the effect of chemotactic signaling among mesenchymal cells. We show that the particular physiology of the mesenchymal cells allows one-dimensional collapse in contrast to the case of bacteria, and that the mesenchymal morphogenesis represents ...
A. J. Majda   +8 more
core   +1 more source

Astrocytic Neuroligins Control Astrocyte Morphogenesis and Synaptogenesis

open access: yesNature, 2017
Astrocytes are complex glial cells with numerous fine cellular processes that infiltrate the neuropil and interact with synapses. The mechanisms that control the establishment of astrocyte morphology are unknown, and it is unclear whether impairing ...
Jeffery A Stogsdill   +8 more
semanticscholar   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

The Kinetic Basis of Morphogenesis

open access: yes, 2015
It has been shown recently (Shalygo, 2014) that stationary and dynamic patterns can arise in the proposed one-component model of the analog (continuous state) kinetic automaton, or kinon for short, defined as a reflexive dynamical system with active ...
Shalygo, Yuri
core   +1 more source

Mechanochemical models for generating biological pattern and form in development [PDF]

open access: yes, 1988
The central issue in development is the formation of spatial patterns of cells in the early embryo. The mechanisms which generate these patterns are unknown.
Maini, P. K.   +2 more
core   +3 more sources

Vertex models: from cell mechanics to tissue morphogenesis

open access: yesPhilosophical Transactions of the Royal Society B: Biological Sciences, 2017
Tissue morphogenesis requires the collective, coordinated motion and deformation of a large number of cells. Vertex model simulations for tissue mechanics have been developed to bridge the scales between force generation at the cellular level and tissue ...
Silvanus Alt, P. Ganguly, G. Salbreux
semanticscholar   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan   +6 more
wiley   +1 more source

Wood identification of Japanese Shinto deity statues in Matsunoo-taisha Shrine in Kyoto by synchrotron X-ray microtomography and conventional microscopy methods

open access: yesJournal of Wood Science, 2019
Research on the wood species of Japanese Buddhist statues has an over 60 years’ history and recently many Buddhist “Ichiboku” statues carved out of a single bole made from the Nara to Heian periods were scientifically revealed to be made of Torreya ...
Suyako Tazuru, Junji Sugiyama
doaj   +1 more source

Myosin IIA-mediated forces regulate multicellular integrity during vascular sprouting [PDF]

open access: yes, 2019
Angiogenic sprouting is a critical process involved in vascular network formation within tissues. During sprouting, tip cells and ensuing stalk cells migrate collectively into the extracellular matrix while preserving cell-cell junctions, forming patent ...
Chen, Christopher S.   +10 more
core   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

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