Results 61 to 70 of about 415,386 (265)

Development of a Synthetic Hydrogel to Foster Microvascularization of an Endometriosis Microphysiological System

open access: yesAdvanced Healthcare Materials, EarlyView.
ABSTRACT The ascent of novel alternative methods in drug development spotlights the dual needs for improved biological fidelity to in vivo, along with reproducibility, especially in regulatory applications. The need for pre‐clinical models of patient‐derived endometriosis lesions motivates the development of a vascularizable, completely synthetic ...
Lauren Pruett   +7 more
wiley   +1 more source

Tuning the Testicular Microenvironment for Enhancing Human Sertoli Cells Maturation and Functionality In Vitro

open access: yesAdvanced Healthcare Materials, EarlyView.
An in vitro testicular model is developed by generating connective tissue equivalents from human dermal fibroblast‐derived microtissues and coupling them with human Sertoli cells or human Sertoli cell spheroids. This engineered microenvironment supports Sertoli cell maturation and functionality, providing a promising platform for studying human ...
Annachiara Scalzone   +4 more
wiley   +1 more source

Evolving gene regulatory networks for cellular morphogenesis

open access: yes, 2005
The generation of pattern and form in a developing organism results from a combination of interacting processes, guided by a programme en- coded in its genome.
Geard, N.   +3 more
core  

Morphogenesis and Social Networks: Relational Steering not Mechanical Feedback

open access: yes, 2013
What is the morphogenetic society? Why do we speak of the ‘morphogenesis’ of society? The concept of morphogenesis (MG) in the social sciences can be traced back to organic system theory.
DONATI, PIERPAOLO, Pierpaolo Donati
core   +1 more source

Microengineered Gradient Hydrogels for Mechanobiology

open access: yesAdvanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong   +4 more
wiley   +1 more source

Mechanisms of morphogenesis /

open access: yes, 2013
Morphogenesis is the set of processes that generate shape and form in the embryo--an important area within developmental biology. An exciting and up-to-the-minute account of the very latest research into the factors that create biological form ...
Davies, Jamie A.
core  

Architectural Morphogenesis Through Topology Optimization

open access: yes, 2018
As architectural designs continue to push boundaries, there is more exploration into the bound shape of architecture within the limits of spaces made for human usability and interaction.
ROBERTO NABONI, INGRID PAOLETTI
core   +1 more source

Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy

open access: yesAdvanced Healthcare Materials, EarlyView.
This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su   +8 more
wiley   +1 more source

Aspects of tissue morphogenesis and organisation in the zebra fish, Brachydanio rerio

open access: yes, 2015
This thesis is mainly concerned with the impact of cellular mechanisms which influence a particular instance of tissue morphogenesis, namely development of the caudal fin of the zebra fish, Brachydanio rerio.
Paul, Jeremy Dane
core  

Live imaging of Drosophila gonad formation reveals roles for Six4 in regulating germline and somatic cell migration [PDF]

open access: yes, 2007
Background: Movement of cells, either as amoeboid individuals or in organised groups, is a key feature of organ formation. Both modes of migration occur during Drosophila embryonic gonad development, which therefore provides a paradigm for understanding ...
Andrew P Jarman   +5 more
core   +1 more source

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