Results 81 to 90 of about 654,596 (326)

Harnessing Fungal Biowelding for Constructing Mycelium‐Engineered Materials

open access: yesAdvanced Engineering Materials, EarlyView.
Mycelium‐bound composites (MBCs) offer low‐carbon alternatives for construction, yet interfacial bonding remains a critical challenge. This review examines fungal biowelding as a biocompatible adhesive, elucidating mycelium‐mediated interfacial mechanisms and their role in material assembly. Strategies to optimize biowelding are discussed, highlighting
Xue Brenda Bai   +2 more
wiley   +1 more source

Substrate Stress Relaxation Regulates Cell‐Mediated Assembly of Extracellular Matrix

open access: yesAdvanced Functional Materials, EarlyView.
Silicone‐based viscoelastic substrates with tunable stress relaxation reveal how matrix mechanics regulates cellular mechanosensing and cell‐mediated matrix remodelling in the stiff regime. High stress relaxation promotes assembly of fibronectin fibril‐like structures, increased nuclear localization of YAP and formation of β1 integrin‐enriched ...
Jonah L. Voigt   +2 more
wiley   +1 more source

Sox8 is essential for vertebrate gastrulation

open access: yesEMBO Reports
Gastrulation is a fundamental developmental process during which germ layers are formed and the body axes are defined by the precise orchestration of cell movements and fate specification. Here, we identify the SOXE transcription factor Sox8 as a pivotal
Sofia Moreira   +2 more
doaj   +1 more source

Standardised imaging pipeline for phenotyping mouse laterality defects and associated heart malformations, at multiple scales and multiple stages

open access: yesDisease Models & Mechanisms, 2019
Laterality defects are developmental disorders resulting from aberrant left/right patterning. In the most severe cases, such as in heterotaxy, they are associated with complex malformations of the heart.
Audrey Desgrange   +4 more
doaj   +1 more source

Mesenchymal adenomatous polyposis coli plays critical and diverse roles in regulating lung development. [PDF]

open access: yes, 2015
BackgroundAdenomatous polyposis coli (Apc) is a tumor suppressor that inhibits Wnt/Ctnnb1. Mutations of Apc will not only lead to familial adenomatous polyposis with associated epithelial lesions, but will also cause aggressive fibromatosis in ...
Bellusci, Saverio   +9 more
core   +1 more source

Molecular Mechanisms of Leaf Morphogenesis.

open access: yesMolecular Plant, 2018
Plants maintain the ability to form lateral appendages throughout their life cycle and form leaves as the principal lateral appendages of the stem.
Fei Du, Chunmei Guan, Yuling Jiao
semanticscholar   +1 more source

Controlling 3D Contractility via Engineered Fibrous Hydrogel Composites

open access: yesAdvanced Functional Materials, EarlyView.
A tunable composite contractile assembly (CCA) is developed that can permit or resist contraction without changing cell‐adhesion and density, unlike collagen whose inherent coupling of these ECM cues limits its use as a platform in contractility studies.
Karen L. Xu   +7 more
wiley   +1 more source

Deep learning-based detection of murine congenital heart defects from µCT scans

open access: yesCommunications Biology
Micro-computed tomography (μCT) provides 3D images of congenital heart defects (CHD) in mice. However, diagnosing CHD from μCT scans is time-consuming and requires clinical expertise. Here, we present a deep learning approach to automatically segment and
Hoa Nguyen   +7 more
doaj   +1 more source

The Morphogenesis Of Evolutionary Developmental Biology [PDF]

open access: yes, 2003
The early studies of evolutionary developmental biology (Evo-Devo) come from several sources. Tributaries flowing into Evo-Devo came from such disciplines as embryology, developmental genetics, evolutionary biology, ecology, paleontology, systematics ...
Gilbert, Scott F.
core   +2 more sources

Abnormal arterial-venous fusions and fate specification in mouse embryos lacking blood flow. [PDF]

open access: yes, 2017
The functions of blood flow in the morphogenesis of mammalian arteries and veins are not well understood. We examined the development of the dorsal aorta (DA) and the cardinal vein (CV) in Ncx1 -/- mutants, which lack blood flow due to a deficiency in a ...
Beckouche, Nathan   +5 more
core   +2 more sources

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