Results 71 to 80 of about 244,442 (332)

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

UV-Cured Inkjet-Printed Silver Gate Electrode with Low Electrical Resistivity

Nanoscale Research Letters, 2017
Inkjet-printed silver gate electrode with low electrical resistivity was fabricated by UV curing method. By adjusting the UV curing time and the distance between the samples and UV lamp, the effects of UV curing conditions on the electrical resistivity ...
Honglong Ning, Yicong Zhou, Zhiqiang Fang, Rihui Yao, Ruiqiang Tao, Jianqiu Chen, Wei Cai, Zhennan Zhu, Caigui Yang, Jinglin Wei, Lei Wang, Junbiao Peng   +11 more
doaj   +1 more source

Research progress in stannous oxide thin film transistors

Cailiao gongcheng, 2020
Due to its unique optical and electrical properties, p-type metal oxide materials stannous oxide has been favored by more and more people in various fields such as catalysis, sensing and optoelectronic devices.This paper focuses on the research and ...
DENG Pei-miao, NING Hong-long, XIE Wei-guang, LIU Xian-zhe, DENG Yu-xi, YAO Ri-hui, PENG Jun-biao   +6 more
doaj   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Space Applications of Solid State Luminescent Phenomena [PDF]

Luminescent phenomena in interplanetary space and moon related to luminescent, thermoluminescent, and cathodoluminescent properties of terrestrial minerals and ...
Weber, J. N., White, E.
core   +1 more source

Can Europium Atoms form Luminescent Centres in Diamond: A combined Theoretical-Experimental Study

, 2019
The incorporation of Eu into the diamond lattice is investigated in a combined theoretical-experimental study. The large size of the Eu ion induces a strain on the host lattice, which is minimal for the Eu-vacancy complex.
Haenen, Ken, Maes, Wouter, Nicley, Shannon S., Raymakers, Jorne, Vanpoucke, Danny E. P.   +4 more
core   +1 more source

Evidence for suppressed mid-Holocene northeastern Australian monsoon variability from coral luminescence [PDF]

, 2014
Summer monsoon rainfall in northeastern (NE) Australia exhibits substantial interannual variability resulting in highly variable river flows. The occurrence and magnitude of these seasonal river flows are reliably recorded in modern inshore corals as ...
Cook, C.G., Hogg, Alan G., Lewis, S.E., Llewellyn, L.E., Lough, J.M., Palmer, Jonathan G., Turney, Chris S.M.   +6 more
core   +2 more sources

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Quantum-Size Effects in the Visible Photoluminescence of Colloidal ZnO Quantum Dots: A Theoretical Analysis

, 2017
In this work we develop a simple theory for the green photoluminescence of ZnO quantum dots (QDs) that allows us to understand and rationalize several experimental findings on fundamental grounds.
Antosiewicz, Tomasz J., Apell, S. Peter, Monreal, R. Carmina   +2 more
core   +1 more source