Results 61 to 70 of about 5,013,487 (292)

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Luminescent Behavior of Sb3+-Activated Luminescent Metal Halide

, 2023
Metal halide perovskites have unparalleled optoelectronic properties and broad application potential and are expected to become the next epoch-making optoelectronic semiconductors.
Bingsuo Zou, Tao Huang
core   +1 more source

Surpassing the 10% efficiency milestone for 1-cm2 all-polymer solar cells

Nature Communications, 2019
Thick film is preferred for sufficient light absorption and tolerant processing but it easily spoils the charge transport in the all-polymer solar cells. Here Fan et al.
Baobing Fan, Wenkai Zhong, Lei Ying, Difei Zhang, Meijing Li, Yanrui Lin, Ruoxi Xia, Feng Liu, Hin-Lap Yip, Ning Li, Yuguang Ma, Christoph J. Brabec, Fei Huang, Yong Cao   +13 more
doaj   +1 more source

Effect of Al₂O₃ Passivation Layer and Cu Electrodes on High Mobility of Amorphous IZO TFT

IEEE Journal of the Electron Devices Society, 2018
In this paper, we present a high mobility amorphous indium-zinc-oxide (a-IZO) thin film transistor (TFT) based on copper (Cu) source/drain electrodes (S/D) and aluminum oxide (Al2O3) passivation layer (PVL).
Shiben Hu, Honglong Ning, Kuankuan Lu, Zhiqiang Fang, Ruiqiang Tao, Rihui Yao, Jianhua Zou, Miao Xu, Lei Wang, Junbiao Peng   +9 more
doaj   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Augmenting and Assaying Nav1.1 Protein Quantity for Dravet Syndrome Therapy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Dravet Syndrome (DS) is a developmental and epileptic encephalopathy predominantly caused by heterozygous loss‐of‐function variants in SCN1A, which encodes Nav1.1. Conserved upstream open reading frames (uORFs) in SCN1A were validated to regulate translation in reporter assays, demonstrating the therapeutic viability of increasing Nav1.1 from ...
Aiswarya Saravanan, Jordan Safran, Anna Loughman, Grace Lin, Shivanshi Vaid, Dana Allababidi, Peter M. Tessier, Louis T. Dang   +7 more
wiley   +1 more source

Development of multidye UV filters for OPVs using luminescent materials [PDF]

, 2017
Luminescence down-shifting (LDS) is used in several photovoltaic technologies aiming to improve the photon conversion efficiency (PCE) of the devices through the increase of the light harvesting in the regions of the electromagnetic spectrum where the ...
Anizelli, Helder Scapin, Duarte, Jose Leonil, Bristow, Noel, Fernandes, Ricardo Vignoto, Kettle, Jeffrey, Laureto, Edson, Kettle, Jeff, Stoichkov, Vasil   +7 more
core   +1 more source

FastNano Liquid: An Automated Platform for Small‐Angle X‐ray Scattering‐Based Materials Discovery

Advanced Engineering Materials, EarlyView.
We present FastNano Liquid, an automated small‐ and wide‐angle X‐ray scattering platform for the combined synthesis and characterization of (nano)materials. The platform is coupled to varied reactor workflows for both in situ studies of reaction kinetics and ex situ screening of synthesis conditions to support machine learning‐guided exploration ...
Pierre‐Baptiste Flandrin, Émeline Cournède, Jens Krarup, Michael Lesa, Foyzul Hasan, Amandine Séné, Arnaud Lahouati, David Benhaiem, Jérémie‐Luc Sanchez, Simon Delacroix, Thierry Gacoin, Fabienne Testard, Damien Faivre, David Carriere, Corinne Chevallard, Olivier Taché, Mark A. Levenstein   +16 more
wiley   +1 more source

Luminescent glasses in art [PDF]

In this study the application of luminescent glasses under UV light in artworks is explored. Several lanthanide oxides were used in the glass composition to obtain different colours.
Almeida, Teresa, Matos, António Pires de, Antunes, Aquino, Oliveira, Rosa Maria de, Ruivo, Andreia   +4 more
core   +1 more source