Results 71 to 80 of about 9,097,966 (350)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Mastering morphology of non-fullerene acceptors towards long-term stable organic solar cells

Nature Communications, 2023
Despite the rapid progress of organic solar cells based on non-fullerene acceptors, simultaneously achieving high power conversion efficiency and long-term stability for commercialization requires sustainable research effort.
Kang An, Wenkai Zhong, Feng Peng, Wanyuan Deng, Ying Shang, Huilei Quan, Hong Qiu, Cheng Wang, Feng Liu, Hongbin Wu, Ning Li, Fei Huang, Lei Ying   +12 more
doaj   +1 more source

Highly Stable Luminous "snakes" from CsPbX3 Perovskite Nanocrystals Anchored on Amine-Coated Silica Nanowires [PDF]

, 2019
CsPbX3 (X = Cl, Br, and I) perovskite nanocrystals (NCs) are known for their exceptional optoelectronic properties, yet the material's instability toward polar solvents, heat, or UV irradiation greatly limits its further applications.
He, L, Jia, M, Jurow, MJ, Liu, Y, Pan, A, Wu, Y, Zhang, Y, Zheng, F   +7 more
core  

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Integrated copper-halide activated scintillator fiber array for remote high-resolution X-ray imaging

Nature Communications
Long-distance transmission scintillator arrays enable high-resolution X-ray imaging and signal transmission in challenging environments such as aerospace machinery, nuclear reactor cores, and complex biological regions.
Hao Zhang, Xiongjian Huang, Tianze Wan, Ruishan Wei, Bozhao Yin, Yakun Le, Shengda Ye, Weiwei Chen, Mingjia Li, Xiudi Xiao, Xiaofeng Liu, Zhiguo Xia, Jianrong Qiu, Zhongmin Yang, Guoping Dong   +14 more
doaj   +1 more source

Effect of Source/Drain Electrodes on the Electrical Properties of Silicon–Tin Oxide Thin-Film Transistors

Nanomaterials, 2018
Ultra-high definition displays have become a trend for the current flat plane displays. In this study, the contact properties of amorphous silicon–tin oxide thin-film transistors (a-STO TFTs) employed with source/drain (S/D) electrodes were ...
Xianzhe Liu, Honglong Ning, Weifeng Chen, Zhiqiang Fang, Rihui Yao, Xiaofeng Wang, Yuxi Deng, Weijian Yuan, Weijing Wu, Junbiao Peng   +9 more
doaj   +1 more source

Can Europium Atoms form Luminescent Centres in Diamond: A combined Theoretical-Experimental Study

, 2019
The incorporation of Eu into the diamond lattice is investigated in a combined theoretical-experimental study. The large size of the Eu ion induces a strain on the host lattice, which is minimal for the Eu-vacancy complex.
Haenen, Ken, Maes, Wouter, Nicley, Shannon S., Raymakers, Jorne, Vanpoucke, Danny E. P.   +4 more
core   +1 more source

The luminescence of yitria stabilized zirconia doped with Bi2O3 [PDF]

, 1984
Yttria stabilized zirconia doped with Bi2O3 shows an efficient luminescence due to the Bi3+ ions.
Blasse, G., Burggraaf, A.J., Winnubst, A.J.A., Zhiran, Hao   +3 more
core   +2 more sources

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Full-color tuning in multi-layer core-shell nanoparticles from single-wavelength excitation

Nature Communications
Lanthanide-based luminescent materials have shown great capabilities in addressing scientific problems encountered in diverse fields. However, achieving full-color switchable output under single-wavelength irradiation has remained a daunting challenge ...
Jinshu Huang, Lili Tao, Haopeng Wei, Haozhang Huang, Qinyuan Zhang, Bo Zhou   +5 more
doaj   +1 more source