Results 41 to 50 of about 2,962,124 (253)
Molecules, 2022 We report development of luminescent ionic salts consisting of the boron ketoiminate structure, which is one of the robust skeletons for expressing aggregation-induced emission (AIE) properties.
Kazumasa Suenaga +3 more
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Probing dark exciton diffusion using photovoltage
Nature Communications, 2017 Exciton diffusion plays a role in many optoelectronic devices. In some materials, this migration cannot be detected using photoluminescence. Mullenbachet al. use photovoltage measurements to extract the diffusion length in organic photovoltaic cells, and
Tyler K. Mullenbach +3 more
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Sensors, 2019 Optical planar waveguide sensors, able to detect and process information from the environment in a fast, cost-effective, and remote fashion, are of great interest currently in different application areas including security, metrology, automotive ...
Jorge Alamán +3 more
doaj +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Eu3+ ion as a luminescent structural probe for studying the biomineralization processes in sol-gel derived bioactive glasses: a preliminary study [PDF]
, 2011 In this thesis we describe the first steps in the development of a novel characterization method, meant to shed some new light on the biomineralization processes that take place on the surfaces of bioactive glasses when they are implanted into biological
Tiozzo, Simone
core
Preparation and luminescent properties of rare earth Eu-doped nano-ZnO composite films on textiles
Journal of Industrial TextilesThis study reports the successful preparation of rare-earth Eu-doped ZnO composite films on cotton fabric, achieving remarkable luminescent properties through the magnetron sputtering method.
Xiaohong Yuan +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source