Results 61 to 70 of about 40,467 (306)
Materials & Design, 2021 Trace amounts of heavy metal ions in the human body are essential for maintaining health. However, heavy metal ion excess or deficiency causes toxicity or disease. This study examines the sensitivity of luminescent europium complexes for the detection of
Xiaozhen Wang +8 more
doaj +1 more source
Development of enhanced techniques for aerodynamic monitoring using pressure-sensitive-paint (PSP) [PDF]
, 2005 N/
Hradil, Jan
core
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Out-of-plane orientation of luminescent excitons in two-dimensional indium selenide
Nature Communications, 2019 Room temperature photoluminescence of most 2D van der Waals semiconductors originate from in-plane dipoles. Here, the authors report a combination of far-field photoluminescence measurements and ab-initio calculations to demonstrate that 2D-InSe flakes ...
Mauro Brotons-Gisbert +7 more
doaj +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
CHIMIA, 1989 The luminescent and higher excited states of [Ru(bpy)3]2⊕ are critically discussed, and compared with new measurements in sol-gel glasses, a lead tin fluorophosphate glass (made at 280 °C), boric acid (230 °C), and polyvinylalcohol film (90 °C).
Renata Reisfeld +3 more
doaj +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Luminescence Resonance Energy Transfer Measurements in Myosin [PDF]
Biophysical Journal, 1998 Myosin is thought to generate force by a rotation between the relative orientations of two domains. Direct measurements of distances between the domains could potentially confirm and quantify these conformational changes, but efforts have been hampered by the large distances involved.
Getz, Elise Burmeister +2 more
openaire +2 more sources