Results 201 to 210 of about 85,967 (327)

Detection of Janus-activated kinase-1 and its interacting proteins by the method of luminescent oxygen channeling

open access: gold, 2017
Xinxin Guo   +7 more
openalex   +2 more sources

Targeting p21‐Positive Senescent Chondrocytes via IL‐6R/JAK2 Inhibition to Alleviate Osteoarthritis

open access: yesAdvanced Science, Volume 12, Issue 11, March 20, 2025.
This study uncovers a novel mechanism behind uneven cartilage degeneration in knee osteoarthritis (OA). Elevated IL‐6R expression activates the IL‐6 pathway, leading to SIRT1 degradation, chondrocyte senescence, and reduced SOX9 activity, which impairs cartilage matrix synthesis. Notably, the JAK inhibitor tofacitinib prevents IL‐6R‐mediated senescence,
Xiang Zhao   +11 more
wiley   +1 more source

Single Platform for Gene and Protein Expression Analyses Using Luminescent Gold Nanoclusters

open access: gold, 2018
Sunil Kumar Sailapu   +4 more
openalex   +1 more source

Delivery of A Chemically Modified Noncoding RNA Domain Improves Dystrophic Myotube Function

open access: yesAdvanced Science, EarlyView.
CYTOR is a pro‐myogenic ncRNA in skeletal muscle. Here, chemical probing of CYTOR, coupled with functional cellular assays identifies exon 2 as an independent myogenic RNA domain. Chemical engineering of CYTOR exon 2 RNA improves pharmacologic properties, including RNA stability and cell‐autonomous immunogenicity.
Zeinabou Niasse‐Sy   +6 more
wiley   +1 more source

Luminescent sensing of conformational integrin activation in living cells. [PDF]

open access: yesCell Rep
Villari G   +8 more
europepmc   +1 more source

Structure and formation of highly luminescent protein-stabilized gold clusters

open access: diamond, 2018
Daniel M. Chevrier   +12 more
openalex   +2 more sources

Cloning and sequence analysis of cDNA for the luminescent protein aequorin. [PDF]

open access: green, 1985
S Inouye   +7 more
openalex   +1 more source

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