Results 211 to 220 of about 5,782,344 (357)

Learned Conformational Space and Pharmacophore Into Molecular Foundational Model

Advanced Science, EarlyView.
The Ouroboros model introduces two orthogonal modules within a unified framework that independently learn molecular representations and generate chemical structures. This design enables flexible optimization strategies for each module and faithful structure reconstruction without prompts or noise.
Lin Wang, Yifan Wu, Hao Luo, Minglong Liang, Yihang Zhou, Cheng Chen, Chris Liu, Jun Zhang, Yang Zhang   +8 more
wiley   +1 more source

Protein-protected luminescent noble metal quantum clusters: an emerging trend in atomic cluster nanoscience [PDF]

, 2012
P. Lourdu Xavier, Kamalesh Chaudhari, Ananya Baksi, Thalappil Pradeep   +3 more
openalex   +1 more source

Applications of colloidal nanocrystals [PDF]

, 2013
Abé, Sofie, Hens, Zeger, Smet, Philippe
core   +1 more source

HSP70 Interactome‐Mediated Proteolysis Targeting Chimera (HSP70‐PROTAC) for Ferroptosis‐Driven Cancer Treatment

Advanced Science, EarlyView.
This study reports a novel targeted protein degradation strategy termed “HSP70‐PROTAC” that recruits Hsc70 complex to a target protein for inducing degradation. Among them, GDAz‐3 exhibits effective GPX4 degradation activity via UPS/CMA processes, triggering ferroptosis‐driven anticancer activity in vitro and in vivo.
Jinyun Dong, Yulong Li, Hui Liang, Zumei Wu, Shiqun Wang, Yichao Wang, Jieyu Xu, Yanning Lan, Maohua Cai, Guangzhao Pan, Haiyan Yang, Kai Miao, Zhe‐Sheng Chen, Fangfang Tao, Xuelei Ma, Jiang‐Jiang Qin   +15 more
wiley   +1 more source

Molecular mechanism of biocompatible clusteroluminogens from citric acid and l-lysine. [PDF]

RSC Adv
Zhang Q, Sun P, Li B.
europepmc   +1 more source

Optical Properties of Nanostructured Silicon [PDF]

, 2010
Albery, Altarelli, Balandin, Baldwin, Banerjee, Batson, Batson, Belomoin, Bianconi, Bianconi, Bley, Botti, Boukai, Brown, Brown, Brus, Buriak, Canham, Chao, Chao, Chao, Chen, Choi, Cichos, Coulthard, Coulthard, Credo, Cullis, Cullis, Dinh, Dixon, du Plessis, Efros, Eisebitt, Eisebitt, Eisebitt, ElShall, English, Fauchet, Fauchet, Faucheux, Feng, Fojtik, Furukawa, Gaponenko, Gensterblum, Germanenko, Giesen, Gong, Hata, Heinrich, Hochbaum, Holmes, Hu, Itoh, Jiang, John, Kane, Kanemitsu, Kanemitsu, Kanemitsu, Kanemitsu, Kanemitsu, Kapaklis, Kapoor, Kasrai, KatIrcIoglu, Khitun, Komuro, Kovalev, Kovalev, Lee, Lehmann, Li, Li, Lie, Lie, Littau, Liu, Liu, Liu, Lu, Macdonald, Macdonald, Mangolini, McCord, Meyer, Mikulec, Osad’ko, Pettifer, Prasher, Rao, Reboredo, Rostron, Sankaran, Schoenfeld, Sham, Sham, Sham, Soderholm, Stevens, Stohr, Stohr, Suda, Suemoto, Sweryda-Krawiec, Sychugov, Tanaka, Tang, Tilley, Timoshenko, Torchynska, Uhlir, Valenta, Valenta, van Buuren, Van Buuren, Venkatasubramanian, Verberk, Vining, Volz, Wilcoxon, Willey, Wolkin, Wu, Wuhn, Zhang, Zimina, Zou   +128 more
core   +1 more source

ITGB1 Regulates Triple‐Negative Breast Cancer Development by Modulating the Tumor Microenvironment

Advanced Science, EarlyView.
ABSTRACT Tumorigenesis and metastasis are frequently attributed to the intricate interplay between cancer cells and the tumor microenvironment (TME). Comprehending the mechanisms and key regulators of cancer‐immune crosstalk in the TME is imperative for developing efficacious immunotherapy.
Nuozi Song, Siqi Chen, Lei Wang, Jessica Dang, Xu Cao, Stephanie Singh, Lu Yang, Jinhui Wang, Steven T. Rosen, Yingyu Wang, Chun‐Wei D. Chen, Cheng Zhang, Mingye Feng   +12 more
wiley   +1 more source

Europium Complex-Loaded Albumin Nanoparticles as Probes for Time-Resolved Luminescent Immunoassay. [PDF]

Biosensors (Basel)
Galaeva Z, Bochkova M, Rayev M, Khramtsov P.   +3 more
europepmc   +1 more source

Nap1L4a Cooperates with Scl/Klf1 to Recruit H2A.Z in Mediating Interactions Among Cis‐Regulatory Elements and Transcription Required for Primitive Erythropoiesis in Zebrafish

Advanced Science, EarlyView.
Nap1l4a is required in erythropoiesis and hypoxia responses via physical interaction with Klf1 and Scl to recruit the histone variant H2A.Z. This facilitates its associated cis‐regulatory element (CRE) remodeling and the consequent chromatin assembly, and activates the transcription of erythroid lineage‐specific genes.
JiaHao Shi, FuMing Lai, Zheng Shen, XiaoYan Zhang, HanFei Wang, WenYe Liu, YunLong Wang, KuanYu Li, GuoLiang Li, YaPing Fang, Jing‐Xia Liu   +10 more
wiley   +1 more source

Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53

Advanced Science, EarlyView.
NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore, Andrea Basile, Stefano Freddi, Irene Schiano Lomoriello, Carlo Ribelle Zucca, Giuseppe Ciossani, Luigi Scietti, Alessandro Cuomo, Simona Ronzoni, Simone Pelicci, Mario Faretta, Elena Zaccheroni, Giuliana Pelicci, Vittoria Matafora, Angela Bachi, Rosalind Helen Gunby, Salvatore Pece, Sara Sigismund, Letizia Lanzetti, Ivan Nicola Colaluca, Pier Paolo Di Fiore   +20 more
wiley   +1 more source