Results 91 to 100 of about 8,015,190 (317)
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
FEBS Open Bio, EarlyView.Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Lump solutions of the fractional Kadomtsev–Petviashvili equation
Fractional Calculus and Applied AnalysisAbstractOf concern is the fractional Kadomtsev–Petviashvili (fKP) equation and its lump solution. As in the classical Kadomtsev–Petviashvili equation, the fKP equation comes in two versions: fKP-I (strong surface tension case) and fKP-II (weak surface tension case).
Handan Borluk +2 more
openaire +4 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela +13 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Time-localized projectors in String Field Theory with E-field
, 2005 We extend the analysis of hep-th/0409063 to the case of a constant electric field turned on the worldvolume and on a transverse direction of a D-brane.
A. Sen +25 more
core +1 more source
Open PhysicsIn this article, the (3+1)-dimensional Hirota–Satsuma–Ito-like equation is investigated by the modified direct method, from which some interaction solutions among lump, stripe solitons, and Jacobi elliptic function wave solutions are obtained, which are ...
Liu Xiaotian +2 more
doaj +1 more source
Solitons in the Calogero model for distinguishable particles
, 2005 We consider a large $- N, $ two-family Calogero model in the Hamiltonian, collective-field approach. The Bogomol'nyi limit appears and the corresponding solutions are given by the static-soliton configurations.
Andrić I. +6 more
core +2 more sources