Results 61 to 70 of about 118,565 (240)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Advances in Mathematical Physics, 2021 It is well known that the celebrated Kadomtsev-Petviashvili (KP) equation has many important applications. The aim of this article is to use fractional KP equation to not only simulate shallow ocean waves but also construct novel spatial structures ...
Bo Xu, Yufeng Zhang, Sheng Zhang
doaj +1 more source
D0-brane tension in string field theory
, 2005 We compute the D0-brane tension in string field theory by representing it as a tachyon lump of the D1-brane compactified on a circle of radius $R$. To this aim, we calculate the lump solution in level truncation up to level L=8.
A. Sen +14 more
core +1 more source
Patterns in Open String Field Theory Solutions [PDF]
, 2002 In open string field theory the kinetic operator mixes matter and ghost sectors, and thus the ghost structure of classical solutions is not universal.
A. Sen +36 more
core +2 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Novel physical nonlinear structures in Saturn’s magnetosphere: Ion-acoustic solitons, lumps, and horseshoe-like nonlinear waves [PDF]
AIP AdvancesIn this paper, new analytical physical solutions to the Kadomtsev–Petviashvili–Bergers’ (KPB) equation in the multicomponent plasmas of Saturn are reported.
Weaam Alhejaili +2 more
doaj +1 more source
The explicit solution and its soliton molecules in the (2+1)-dimensional pKP–BKP equation
Results in Physics, 2022 One N-soliton solution of the (2+1)-dimensional combined potential Kadomtsev–Petviashvili (pKP) with B-type Kadomtsev–Petviashvili (BKP) equation, which involves the soliton molecules, is constructed with the aid of its Hirota bilinear form.
Zheng-Yi Ma +3 more
doaj +1 more source
An equitable approach to the payment scheduling problem in project management [PDF]
, 2000 This study reports on a new approach to the payment scheduling problem. In this approach, the amount and timing of the payments made by the client and received by the contractor are determined so as to achieve an equitable solution.
Cebelli, Serkan +2 more
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Gravitational Field of a Spinning Cosmic String
, 2008 We study the effect of internal space rotation on the gravitational properties of infinite straight and stationary cosmic string. From the approximate solution of Einsten equations for the spinning Q-lump string we obtain long range gravitational ...
A. Abrikosov +7 more
core +1 more source