Lung - Open Access .click

Results 1 to 10 of about 2,198,200 (198)

Editorial: Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2023 Guidelines for COPD, Including COVID-19, Climate Change, and Air Pollution

Medical Science Monitor, 2023
The 2023 Global Initiative for Chronic Obstructive Lung Disease (GOLD) report includes relevant topics from the clinician’s perspective and evidence published on chronic obstructive pulmonary disease (COPD) since GOLD 2017. The World Health Organization (
D. Parums
semanticscholar +1 more source

Time Course of Lung Changes On Chest CT During Recovery From 2019 Novel Coronavirus (COVID-19) Pneumonia

Radiology, 2020
Background Chest CT is used to assess the severity of lung involvement in COVID-19 pneumonia. Purpose To determine the change in chest CT findings associated with COVID-19 pneumonia from initial diagnosis until patient recovery.
F. Pan +10 more
semanticscholar +2 more sources

Pembrolizumab plus Chemotherapy in Metastatic Non–Small‐Cell Lung Cancer

New England Journal of Medicine, 2018
BACKGROUND First‐line therapy for advanced non–small‐cell lung cancer (NSCLC) that lacks targetable mutations is platinum‐based chemotherapy. Among patients with a tumor proportion score for programmed death ligand 1 (PD‐L1) of 50% or greater ...
L. Gandhi +28 more
semanticscholar +1 more source

Lung cancer immunotherapy: progress, pitfalls, and promises

Molecular Cancer, 2023
Lung cancer is the primary cause of mortality in the United States and around the globe. Therapeutic options for lung cancer treatment include surgery, radiation therapy, chemotherapy, and targeted drug therapy.
Aritraa Lahiri +7 more
semanticscholar +1 more source

Nivolumab versus Docetaxel in Advanced Nonsquamous Non-Small-Cell Lung Cancer.

New England Journal of Medicine, 2015
BACKGROUND Nivolumab, a fully human IgG4 programmed death 1 (PD-1) immune-checkpoint-inhibitor antibody, disrupts PD-1-mediated signaling and may restore antitumor immunity.
H. Borghaei +27 more
semanticscholar +1 more source

Pembrolizumab for the treatment of non-small-cell lung cancer.

New England Journal of Medicine, 2015
BACKGROUND We assessed the efficacy and safety of programmed cell death 1 (PD-1) inhibition with pembrolizumab in patients with advanced non-small-cell lung cancer enrolled in a phase 1 study.
E. Garon +26 more
semanticscholar +1 more source

Lung adenocarcinoma promotion by air pollutants

Nature, 2023
A complete understanding of how exposure to environmental substances promotes cancer formation is lacking. More than 70 years ago, tumorigenesis was proposed to occur in a two-step process: an initiating step that induces mutations in healthy cells ...
William Hill +326 more
semanticscholar +1 more source

Mutational landscape determines sensitivity to PD-1 blockade in non–small cell lung cancer

Science, 2015
Immune checkpoint inhibitors, which unleash a patient’s own T cells to kill tumors, are revolutionizing cancer treatment. To unravel the genomic determinants of response to this therapy, we used whole-exome sequencing of non–small cell lung cancers ...
N. Rizvi +23 more
semanticscholar +1 more source

Reduced Lung-Cancer Mortality with Volume CT Screening in a Randomized Trial.

New England Journal of Medicine, 2020
BACKGROUND There are limited data from randomized trials regarding whether volume-based, low-dose computed tomographic (CT) screening can reduce lung-cancer mortality among male former and current smokers.
H. D. de Koning +23 more
semanticscholar +1 more source

Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International As

Circulation, 2009
A cluster of risk factors for cardiovascular disease and type 2 diabetes mellitus, which occur together more often than by chance alone, have become known as the metabolic syndrome.
K. G. M. M. Alberti +9 more
semanticscholar +1 more source

pathology
biology
environmental science

computer science
radiology
surgery

engineering
anatomy
physics