Results 41 to 50 of about 2,954,568 (313)

Exposure to TiO₂ Nanostructured Aerosol Induces Specific Gene Expression Profile Modifications in the Lungs of Young and Elderly Rats

Nanomaterials, 2021
Although aging is associated with a higher risk of developing respiratory pathologies, very few studies have assessed the impact of age on the adverse effects of inhaled nanoparticles. Using conventional and transcriptomic approaches, this study aimed to
Sarah A. Valentino, Laëtitia Chézeau, Carole Seidel, Sylvie Sébillaud, Mylène Lorcin, Monique Chalansonnet, Frédéric Cosnier, Laurent Gaté   +7 more
doaj   +1 more source

Simvastatin reduces endotoxin-induced acute lung injury by decreasing neutrophil recruitment and radical formation. [PDF]

, 2012
Treatment of acute lung injury (ALI) remains an unsolved problem in intensive care medicine. As simvastatin exerts protective effects in inflammatory diseases we explored its effects on development of ALI and due to the importance of neutrophils in ALI ...
Vijayan, Santosh, Mörgelin Matthias, Grommes Jochen, Köppel, Thomas, Grommes, Jochen, Binneboesel, Marcel, Mörgelin, Matthias, Helene Hartwig (158829), Weber, Christian, Matthias Mörgelin (109607), Rolf Dembinski, Santosh Vijayan, Jochen Grommes (158815), Söhnlein, Oliver, Dembinski, Rolf, Drechsler, Maik, Thomas Andreas Koeppel, Oliver Soehnlein, Moergelin, Matthias, Vijayan Santosh, Dembinski Rolf, Weber Christian, Santosh Vijayan (158820), Koeppel, Thomas Andreas, Binnebösel, Marcel, Christian Weber (86566), Maik Drechsler (158824), Michael Jacobs, Maik Drechsler, Lund University., Rolf Dembinski (12675), Thomas Andreas Koeppel (158847), Koeppel Thomas Andreas, Marcel Binnebösel, Matthias Mörgelin, Jacobs, Michael, Jacobs Michael, Binnebösel Marcel, Oliver Soehnlein (158864), Michael Jacobs (105163), Hartwig Helene, Jochen Grommes, Mörgelin, Matthias,, Helene Hartwig, Marcel Binnebösel (158855), Soehnlein, Oliver, Hartwig, Helene, Drechsler Maik, Soehnlein Oliver, Christian Weber   +49 more
core   +2 more sources

Risk of development of brain metastases according to the IASLC/ATS/ERS lung adenocarcinoma classification in locally advanced and metastatic disease

, 2021
Introduction: Brain metastases (BM) are frequent among lung cancer patients, affecting prognosis and quality of life. The International Association for the Study of Lung Cancer (IASLC), American Thoracic Society (ATS) and European Respiratory Society ...
Caballé Pérez, Enrique, Escamilla, Ixel, Pereira García, Ariana, Díaz-García, Diego, Lara-Mejía, Luis, Rolfo, Christian Diego, Estuardo Raez, Luis, Avilés Salas, Alejandro, Costa Rosell, Rafael, Arrieta, Oscar, Cardona, Andrés Felipe, Enrique Caballé Pérez, Andrés F. Cardona, Ixel Escamilla, Ariana Pereira García, Oscar Arrieta, Luis E. Raez, Christian Rolfo, Alejandro Avilés Salas, Diego Díaz-García, Luis Lara-Mejía, Rafael Rosell   +21 more
core   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Efficacy of bevacizumab through an indwelling pleural catheter in non-small cell lung cancer patients with symptomatic malignant pleural effusion

BMC Pulmonary Medicine
Background Several studies have indicated that intrapleural infusion of bevacizumab is an effective treatment for non-small cell lung cancer (NSCLC) with malignant pleural effusion (MPE).
Hao Zeng, Yuanyuan Zhang, Sihan Tan, Qin Huang, Xin Pu, Panwen Tian, Yalun Li   +6 more
doaj   +1 more source

Integrated proteomic and transcriptomic profiling of mouse lung development and Nmyc target genes

Molecular Systems Biology, 2007
Although microarray analysis has provided information regarding the dynamics of gene expression during development of the mouse lung, no extensive correlations have been made to the levels of corresponding protein products.
Brian Cox, Thomas Kislinger, Dennis A Wigle, Anitha Kannan, Kevin Brown, Tadashi Okubo, Brigid Hogan, Igor Jurisica, Brendan Frey, Janet Rossant, Andrew Emili   +10 more
doaj   +1 more source

Simvastatin regulates CXC chemokine formation in streptococcal M1 protein-induced neutrophil infiltration in the lung

, 2011
Swedish Medical Research Council [2009-4872]; Crafoordska stiftelsen; Einar och Inga Nilssons stiftelse; Harald och Greta Jaenssons stiftelse; Greta och Johan Kocks stiftelser; Froken Agnes Nilssons stiftelse; Franke och Margareta Bergqvists stiftelse ...
Rahman, Milladur, Zhongquan Qi, 齐忠权, Thorlacius, Henrik, Su Zhang, Milladur Rahman, Songen Zhang, Zhang, Su, Zhang, Songen, Herwald, Heiko, Qi, Zhongquan, Heiko Herwald, Henrik Thorlacius, Rahman, Milladur,, Zhang, Songen,, Thorlacius, Henrik,, Zhang, Su,, Lund University., Herwald, Heiko,   +18 more
core   +1 more source

Palliative Care in Lung Cancer

, 2021
The Lung cancer rate in all cancer types is 21% in men and 5 % in women in European Union Countries. Smoking is the most important factor of lung cancer etiology [1]. The rate of Turkey is found 63% in men and 14% in women in 1988.
Dincer, Selcuk, Ozyalcin, Suleyman
core   +1 more source

Evidence‐Based Clinical Practice Guidelines for the Management of Pediatric Febrile Neutropenia: Resource‐Sensitive Recommendations for the Asian Continent

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Febrile neutropenia (FN) is a frequent and serious complication in children receiving cancer therapy. Standardizing FN management across Asia is challenging due to variable healthcare infrastructure, diagnostic capacity, and infection patterns; however, it could improve resource use and patient outcomes.
Joliza Patricia Cañeba, Shweta Bansal, Tea Reljic, Allyne Montecillo‐Aguelo, Hamidah Alias, Farrah Amaranto, Maria Stella Aquino‐Calingasan, Bambang Ardianto, Eggi Arguni, Sally Blair, Thi Tam Dang, Maria Beatriz Gepte, Samanmalee Gunasekara, Andini Handayani, Miriam Kimpo, Catherine G. Lam, Nawachai Lertvivatpong, Sergio Licona, Ana Loseo, Ratha Mlis, Vivian Moreno Berrio, Nguyen Hoai Anh, Anna Lisa Ong‐Lim, Ha Thu Pham, Krishna Sagar Sharma, Bun Sereyleak, Sally Jane G. Velasco‐Aro, Su Yadana, Ambuj Kumar, Sheena Mukkada   +29 more
wiley   +1 more source