Results 41 to 50 of about 4,049,611 (290)

Exposure to TiO₂ Nanostructured Aerosol Induces Specific Gene Expression Profile Modifications in the Lungs of Young and Elderly Rats

Nanomaterials, 2021
Although aging is associated with a higher risk of developing respiratory pathologies, very few studies have assessed the impact of age on the adverse effects of inhaled nanoparticles. Using conventional and transcriptomic approaches, this study aimed to
Sarah A. Valentino, Laëtitia Chézeau, Carole Seidel, Sylvie Sébillaud, Mylène Lorcin, Monique Chalansonnet, Frédéric Cosnier, Laurent Gaté   +7 more
doaj   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Efficacy of bevacizumab through an indwelling pleural catheter in non-small cell lung cancer patients with symptomatic malignant pleural effusion

BMC Pulmonary Medicine
Background Several studies have indicated that intrapleural infusion of bevacizumab is an effective treatment for non-small cell lung cancer (NSCLC) with malignant pleural effusion (MPE).
Hao Zeng, Yuanyuan Zhang, Sihan Tan, Qin Huang, Xin Pu, Panwen Tian, Yalun Li   +6 more
doaj   +1 more source

Integrated proteomic and transcriptomic profiling of mouse lung development and Nmyc target genes

Molecular Systems Biology, 2007
Although microarray analysis has provided information regarding the dynamics of gene expression during development of the mouse lung, no extensive correlations have been made to the levels of corresponding protein products.
Brian Cox, Thomas Kislinger, Dennis A Wigle, Anitha Kannan, Kevin Brown, Tadashi Okubo, Brigid Hogan, Igor Jurisica, Brendan Frey, Janet Rossant, Andrew Emili   +10 more
doaj   +1 more source

Folk Song 1 [PDF]

, 2012
.wav and .mp3 versions of audio fileThe lyrics state, “If there were no yaks on the mountains, the mountains would not be beautiful, and if there were no gentlemen and ladies in the village, the village would not be pleasant.” This song is sung at public
Lung rtogs dge 'dzin
core   +1 more source

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

Effect of photobiomodulation in the balance between effector and regulatory T cells in an experimental model of COPD

Frontiers in Medicine
IntroductionCurrently, Chronic Obstructive Pulmonary Disease (COPD) has a high impact on morbidity and mortality worldwide. The increase of CD4+, CD8+ cells expressing NF-κB, STAT4, IFN-γ and perforin are related to smoking habit, smoking history ...
Auriléia Aparecida de Brito, Auriléia Aparecida de Brito, Karine Zanella Herculano, Karine Zanella Herculano, Cristiano Rodrigo de Alvarenga-Nascimento, Cintia Estefano-Alves, Cinthya Cosme Gutierrez Duran, Rodrigo Labat Marcos, José Antonio Silva Junior, Maria Cristina Chavantes, Stella Regina Zamuner, Flávio Aimbire, Laia Lladó-Pelfort, Albert Gubern, Albert Gubern, Anna Fàbrega, Anna Fàbrega, Anna Fàbrega, Renata Kelly da Palma, Renata Kelly da Palma, Renata Kelly da Palma, Renata Kelly da Palma, Ana Paula Ligeiro de Oliveira   +22 more
doaj   +1 more source

Lung contusion

Lung India, 2018
Lung contusion usually follows blunt trauma to the chest. If not properly diagnosed and adequately treated, it could at times be fatal as well. This case is being presented to highlight the radiological findings of this condition.
Padmanabhan Arjun, Akbar Abdul Najeeb, Rahul Ramachandran   +2 more
openaire   +3 more sources

Pulmonary Dysfunction Is Associated With Sleep Study Abnormalities in Children With Sickle Cell Disease: A Multicenter Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pulmonary dysfunction and sleep abnormalities are common in children with sickle cell disease (SCD) and are associated with worse clinical outcomes. Whether spirometry abnormalities are associated with polysomnography (PSG) findings remains unclear.
Ammar Saadoon Alishlash, Anis Rabbani Nourani, A. K. M. Fazlur Rahman, Dima Ezmigna, Tarig Ali‐Dinar   +4 more
wiley   +1 more source