Results 51 to 60 of about 2,954,568 (313)

Effect of photobiomodulation in the balance between effector and regulatory T cells in an experimental model of COPD

Frontiers in Medicine
IntroductionCurrently, Chronic Obstructive Pulmonary Disease (COPD) has a high impact on morbidity and mortality worldwide. The increase of CD4+, CD8+ cells expressing NF-κB, STAT4, IFN-γ and perforin are related to smoking habit, smoking history ...
Auriléia Aparecida de Brito, Auriléia Aparecida de Brito, Karine Zanella Herculano, Karine Zanella Herculano, Cristiano Rodrigo de Alvarenga-Nascimento, Cintia Estefano-Alves, Cinthya Cosme Gutierrez Duran, Rodrigo Labat Marcos, José Antonio Silva Junior, Maria Cristina Chavantes, Stella Regina Zamuner, Flávio Aimbire, Laia Lladó-Pelfort, Albert Gubern, Albert Gubern, Anna Fàbrega, Anna Fàbrega, Anna Fàbrega, Renata Kelly da Palma, Renata Kelly da Palma, Renata Kelly da Palma, Renata Kelly da Palma, Ana Paula Ligeiro de Oliveira   +22 more
doaj   +1 more source

Impact of Initial Treatment Setting on Survival in Relapsed Pediatric and AYA Bone Sarcomas: A Secondary Analysis of a Prospective Clinical Trial

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Outcomes in relapsed or refractory pediatric and AYA bone sarcomas remain poor, and the impact of early referral to specialized sarcoma centers on survival is unclear. Early centralization of care may improve local and systemic treatment quality, but evidence in this population is limited.
Justyna Antoniuk‐Majchrzak, Katarzyna Bilska, Tomasz Koziński, Jadwiga Węcławek‐Tompol, Dorota Sega‐Pondel, Radosław Chaber, Wanda Badowska, Katarzyna Rosłan, Hanna Koseła‐Paterczyk, Anna Raciborska   +9 more
wiley   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Hyponatremia as a “red flag” for concurrent meningitis in pulmonary cryptococcosis: a risk stratification model

BMC Neurology
Background Pulmonary cryptococcosis (PC) is increasingly diagnosed in human immunodeficiency virus (HIV)-negative and apparently immunocompetent individuals.
Bich-Ngoc T. Nguyen, Hoang-Anh Nguyen-Cong, Mai-Anh Nguyen, Minh-Phuong Duong, Thi-Chang Hoang, Van-Luong Dinh   +5 more
doaj   +1 more source

White Tea Intake Abrogates Markers of Streptozotocin-Induced Prediabetes Oxidative Stress in Rat Lungs’

Molecules, 2021
Prediabetes (PrDM) is a prodromal stage of diabetes mellitus (DM) with an increasing prevalence worldwide. During DM progression, individuals gradually develop complications in various organs.
Ana C. Silveira, Luís Rato, Pedro Fontes Oliveira, Marco G. Alves, Branca M. Silva   +4 more
doaj   +1 more source

Lung-specific GRN

, 2022
Lung-specific gene regulatory network (GRN) generated using CoDeS3D.
Evgeniia Golovina (4441837)
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The impact of cytomegalovirus coinfection on tuberculosis in the mouse model

BMC Infectious Diseases
Background Tuberculosis (TB) remains a major global health challenge, with 10.6 million new cases and 1.3 million deaths annually. HIV coinfection is a well-known risk factor in high-burden regions, but emerging evidence suggests that other viral ...
Jaqueline Marschner, Sebastian Marwitz, Lars Eggers, Linda von Borstel, Lara Buer, David Hertz, Torsten Goldmann, Eleonore Ostermann, Wolfram Brune, Bianca E. Schneider   +9 more
doaj   +1 more source

CD8 T cells promote heart failure progression in mice with preexisting left ventricular dysfunction

Frontiers in Immunology
IntroductionEven under the standard medical care, patients with left ventricular (LV) failure or heart failure (HF) often progress to pulmonary hypertension and right ventricular (RV) hypertrophy.
Dongzhi Wang, Dongzhi Wang, Xinyu Weng, Xinyu Weng, Wenhui Yue, Linlin Shang, Linlin Shang, Yidong Wei, John S. Clemmer, Yawei Xu, Yingjie Chen, Yingjie Chen   +11 more
doaj   +1 more source

Systems Biology and Bile Acid Signalling in Microbiome-Host Interactions in the Cystic Fibrosis Lung

Antibiotics, 2021
The study of the respiratory microbiota has revealed that the lungs of healthy and diseased individuals harbour distinct microbial communities. Imbalances in these communities can contribute to the pathogenesis of lung disease. How these imbalances occur
David F. Woods, Stephanie Flynn, Jose A. Caparrós-Martín, Stephen M. Stick, F. Jerry Reen, Fergal O’Gara   +5 more
doaj   +1 more source