Results 61 to 70 of about 2,954,568 (313)

Evaluation of bexarotene (Targretin (R)) in combination with cisplatin and vinorelbine in chemotherapy-naive patients with advanced stage IIIb/IV non-small cell lung cancer (NSCLC)

, 2005
Great Poland Lung Dis Ctr, Poznan, PolandUniversidade Federal de São Paulo, São Paulo, BrazilMed Univ Gdansk, Gdansk, PolandPavlov State Med Univ, St Petersburg, RussiaMeir Hosp, Inst Oncol, Kefar Sava, IsraelLigand Pharmaceut Inc, San Diego, CA ...
Negro-Vilar, A., Ramlau, R., Hao, D., Gottfried, M., Zatloukal, P., Mabry, M., Tadokoro, H., Jassem, J., Orlov, S., Dziewanowska, Z.   +9 more
core   +1 more source

Lung volume recruitment maneuvers and respiratory system mechanics in mechanically ventilated mice [PDF]

, 2009
The study aim was to establish how recruitment maneuvers (RMs) influence lung mechanics and to determine whether RMs produce lung injury. Healthy BALB/c mice were allocated to receive positive end-expiratory pressure (PEEP) at 2 or 6 cmH2O and volume ...
Sly, P.D., Hantos, Z, Sly, Peter D., Berry, L.J., Turner, D.J., Zosky, G R, Cannizzaro, V; https://orcid.org/, Turner, Debra J., Hantos, Zoltan, Cannizzaro, V., Berry, Luke J., Nicholls, P.K., Hantos, Z., Nicholls, P K, Sly, P D, Zosk, G.R., Zosky, Graeme R., Berry, L J, Cannizzaro, Vincenzo, Nicholls, Phillip K., Turner, D J   +20 more
core   +1 more source

The effect of lung biopsy on lung function in diffuse lung disease [PDF]

European Respiratory Journal, 2000
The aim of this study was to investigate the effect on lung function of lung biopsy used in the diagnosis of diffuse lung disease carried out by an open procedure or by video-assisted thoracoscopy. One hundred and sixteen patients with diffuse lung disease who attended the Royal Brompton Hospital were studied retrospectively.
Z, Daniil, F C, Gilchrist, S J, Marciniak, P, Pantelidis, P, Goldstraw, U, Pastorino, R M, du Bois   +6 more
openaire   +2 more sources

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Lung

, 1992
Performance in the B. Iden Payne Theatre (UT-Austin). Choreography by Yacov Sharir (The Egg), Jose Luis Bustamante (Lung). See full record (link below) for more details.Theatre and Dance46 minutes: 21 minutes/25 minutes.
Sharir Dance Company
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The Role of Lung Microbiome in Fibrotic Interstitial Lung Disease—A Systematic Review

Biomolecules
Interstitial Lung Disease (ILD) involves lung disorders marked by chronic inflammation and fibrosis. ILDs include pathologies like idiopathic pulmonary fibrosis (IPF), connective tissue disease-associated ILD (CTD-ILD), hypersensitivity pneumonitis (HP ...
Ruxandra Puiu, Nicoleta Stefania Motoc, Sergiu Lucaciu, Maria Victoria Ruta, Ruxandra-Mioara Rajnoveanu, Doina Adina Todea, Milena Adina Man   +6 more
doaj   +1 more source

Evidence supporting a role for circulating macrophages in the regression of vascular remodeling following sub‐chronic exposure to hemoglobin plus hypoxia

Pulmonary Circulation, 2021
Macrophages are a heterogeneous population with both pro‐ and anti‐inflammatory functions play an essential role in maintaining tissue homeostasis, promoting inflammation under pathological conditions, and tissue repair after injury.
Vijaya Karoor, Delaney Swindle, David I Pak, Julie Harral, Derek Strassheim, Mehdi A Fini, Edward Dempsey, Kurt R Stenmark, Kathryn Hassell, Rachelle Nuss, Paul W. Buehler, David C. Irwin   +11 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Spontaneous peristaltic airway contractions propel lung liquid through the bronchial tree of intact and fetal lung explants [PDF]

, 2000
Spontaneous contractions of the fetal airways are a well recognized but poorly characterized phenomenon. In the present study spontaneous narrowing of the airways was analyzed in freshly isolated lungs from early to late gestation in fetal pigs and ...
Schittny, Johannes C., Miserocchi, Giuseppe, Sparrow, Malcolm P., Schittny JC, Miserocchi G, Sparrow MP   +5 more
core   +2 more sources