Results 81 to 90 of about 2,638,123 (318)

Analysis of lung surfactant phosphatidylcholine metabolism in transgenic mice using stable isotopes [PDF]

, 2011
Stable isotope labelling of lipid precursors coupled with mass spectrometry-based lipidomic analyses and determination of isotope enrichment in substrate, intermediate and product pools provide the parameters needed to determine absolute flux rates ...
Grielof Koster, Koster, G., Howard W. Clark, Clark, Howard, Anthony D. Postle, Neil G. Henderson, Henderson, N.J., Alan N. Hunt, Postle, A.D., Hunt, A.N.   +9 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

THE TREATMENT EFFECT OF OXYTETRACYCLINE AND VITAMIN C IN AN EPISODE OF PARAINFLUENZA SHEEP IN TIMIS COUNTY [PDF]

Medicamentul Veterinar, 2017
Sheep parainfluenza It is a disease with high diffusibility, sometimes with fatal serious, especially youth. It is caused by parainfluenza 3 virus (PI-3), identical to the bovine parainfluenza virus isolate, in combination with certain bacteria.
Stancu, A
doaj  

The association between blood coagulation activity and lung function: a population-based study [PDF]

, 2010
<p><b>Background:</b> Increased in susceptibility to thrombotic disease may be associated with lower lung function. If causal, this association may suggest an area for development of new interventions for lung disease.
Lowe, G.D.O., Lorna Clark, Clark, L., Sarah A Lewis, Andrew W Fogarty, Tricia M McKeever, John Britton, Fogarty, A.W., Lewis, S.A., Gordon D O Lowe, Britton, J., Sarah A. Lewis, McKeever, T.M., Gordon D. O. Lowe, Tricia M. McKeever, Reitsma, P.H., Andrew W. Fogarty   +16 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Comparison of three Radiotherapy Techniques Volumetric Modulated Arc Therapy with Variable and Constant Dose Rate and Intensity-Modulated Radiotherapy for the Irradiation of Five Cancer Sites [PDF]

Journal of Biomedical Physics and Engineering
Background: Volumetric modulated arc therapy (VMAT) is mostly considered due to its superior tumor coverage and sparing of organs at risk (OAR) with shorter treatment delivery time.Objective: This study aimed to explore the feasibility and potential ...
Varsha Raghunathji Gedam, Anirudh Pradhan   +1 more
doaj   +1 more source

Risk of development of brain metastases according to the IASLC/ATS/ERS lung adenocarcinoma classification in locally advanced and metastatic disease

, 2021
Introduction: Brain metastases (BM) are frequent among lung cancer patients, affecting prognosis and quality of life. The International Association for the Study of Lung Cancer (IASLC), American Thoracic Society (ATS) and European Respiratory Society ...
Caballé Pérez, Enrique, Escamilla, Ixel, Pereira García, Ariana, Díaz-García, Diego, Lara-Mejía, Luis, Rolfo, Christian Diego, Estuardo Raez, Luis, Avilés Salas, Alejandro, Costa Rosell, Rafael, Arrieta, Oscar, Cardona, Andrés Felipe   +10 more
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Newfoundland Lung Association Newsletter; Lung Association of Newfoundland and Labrador Newsletter

, 1982
The Northern Light, Summer 1982Contents Page -- The Cross of Lorraine or Double-Barred Cross -- Obituaries -- Editorial: 1982, A Year to Remember / E. G. House -- His Hon. W. Anthony Paddon, C.M. M.D.
Newfoundland Lung Association
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source