Results 181 to 190 of about 4,650,441 (339)

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Editorial: Model organisms in respiratory pharmacology 2023

Frontiers in Pharmacology
Alexandra McCarron, Alexandra McCarron, Alexandra McCarron, Ranu Surolia, Livia Ruffini   +4 more
doaj   +1 more source

III. On the elasticity of the lungs

James K. Carson
openalex   +1 more source

The part played by the lungs in the oxidative processes of the body [PDF]

, 1913
C. Lovatt Evans, E. H. Starling
openalex   +1 more source

Paraventricular nucleus CRH neurons regulate acute lung injury via sympathetic nerve-neutrophil axis. [PDF]

Nat Commun
Li H, Liu T, Wang Y, Miao XM, Xiong YY, Zhao Q, Shen WY, Su FH, Chen K, Dai RP.   +9 more
europepmc   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

The production and removal of oedema fluid in the lung after exposure to carbonyl chloride (phosgene) [PDF]

, 1946
G. R. Cameron, F. C. Courtice
openalex   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Single versus double lung transplantation outcomes in artificial stone silicosis: a single-centre retrospective cohort study. [PDF]

BMJ Open Respir Res
Dotan M, Rosengarten D, Azem K, Fein S, Shostak Y, Shitenberg D, Peysakhovich Y, Barac YD, Fireman E, Blanc P, Shtraichman O, Kramer MR.   +11 more
europepmc   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source