Results 221 to 230 of about 4,776,663 (339)

The role of TIPE2 in hemorrhagic shock-induced acute lung injury. [PDF]

Acta Cir Bras
Rong YY, Li YW, Yang SY, Liu SY, Dong YH, Du HB, Xu X, Zhao ZG, Jiang LN.   +8 more
europepmc   +1 more source

RNF20 links the DNA damage response and metabolic rewiring in lung cancer through HIF1α [PDF]

Hao Liu, Yongqin Tang, Anshu Anjali Singh, Joaquim S. L. Vong, Julio Cordero, Arthur Mathes, Rui Gao, Yanhan Jia, Boyan K. Garvalov, Till Acker, Gernot Poschet, Rüdiger Hell, Marc A. Schneider, Joerg Heineke, Thomas Wieland, Guillermo Barreto, Adelheid Cerwenka, Michael Potente, Sofia‐Iris Bibli, Rajkumar Savai, Gergana Dobreva   +20 more
openalex   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Lung Cancer in Never-Smokers: Risk Factors, Driver Mutations, and Therapeutic Advances. [PDF]

Diagnostics (Basel)
Chen PM, Huang YH, Li CY.
europepmc   +1 more source

Lung Immune Prognostic Index-Based Predictive Score in Advanced Non-Small Cell Lung Cancer with a Programmed Death Ligand-1 Tumor Proportion Score ≥ 50% [PDF]

Ari Raphael, Ayelet Kamm Feldman, Irina Lazarev, Waleed Kian, Nir Peled, Keren Hod, Walid Shalata, Elizabeth Dudnik   +7 more
openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Dosimetric Challenges of Small Lung Lesions in Low-Density Tissue Treated with Stereotactic Body Radiation Therapy. [PDF]

J Clin Med
Das IJ, Ding M, Abazeed ME.
europepmc   +1 more source

P3.13D.09 Prevalence and Prognostic Impact of SEZ6 Expression in a Real-World Cohort of Patients with Small-Cell Lung Cancer [PDF]

Shui Wang, Aiping Luo, Nusrat Choudhury, L. Wang, Dongsheng Xu, Fang Jiang, Lisa Roberts-Rapp, Yookyung Christy Choi, Meng Cai, Nandini Rudra-Ganguly, Peter Ansell, L. Paz-Ares, L.A. Byers   +12 more
openalex   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Editorial: Model organisms in respiratory pharmacology 2023

Frontiers in Pharmacology
Alexandra McCarron, Alexandra McCarron, Alexandra McCarron, Ranu Surolia, Livia Ruffini   +4 more
doaj   +1 more source