Results 111 to 120 of about 273,871 (338)

Lung: Translocations in Adenocarcinoma [PDF]

open access: yesAtlas of Genetics and Cytogenetics in Oncology and Haematology, 2015
Review on Lung: Translocations in Adenocarcinoma, with data on clinics, and the genes involved.
openaire   +3 more sources

Screening and validation of tsRNAs associated with lung adenocarcinoma

open access: yes陆军军医大学学报
Objective‍ To explore the roles of transfer RNA-derived small RNAs (tsRNAs) in the oncogenesis and progression of lung adenocarcinoma by analyzing the differential expression of tsRNAs in lung adenocarcinoma and the relationship between the expression ...
LU Chunli, SHAN Yifan, XIE Weijia
doaj   +1 more source

“Therapies Through Gut:” Targeted Drug Delivery for Non‐Gastrointestinal Diseases by Oral Administration

open access: yesAdvanced Healthcare Materials, EarlyView.
Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray   +2 more
wiley   +1 more source

Systematic Comparison of Commercial Uranyl‐Alternative Stains for Negative‐ and Positive‐Staining Transmission Electron Microscopy of Organic Specimens

open access: yesAdvanced Healthcare Materials, EarlyView.
Negative‐ and positive‐staining TEM is essential for rapid nanometer‐resolution characterization of organic specimens ranging from nanoparticles to cells. Uranyl salts are widely used negative‐/positive‐stains but are radioactive and highly toxic to users and the environment.
Vera M. Kissling   +4 more
wiley   +1 more source

Inhibition of NRF1/ABCC1 improves chemosensitivity of human lung adenocarcinoma cell lines to cisplatin [PDF]

open access: yesJichu yixue yu linchuang
Objective To explore the effect of nuclear respiratory factor 1(NRF1) activation of ATP binding cassette transporter C1(ABCC1) transcription on cisplatin resistance in lung adenocarcinoma cells and its potential mechanisms.
CHEN Qingxia, LIANG Yuling, LUO Yalan, NIU Bin
doaj   +1 more source

Digitonin‐Loaded Nanoscale Metal–Organic Framework for Mitochondria‐Targeted Radiotherapy‐Radiodynamic Therapy and Disulfidptosis

open access: yesAdvanced Materials, EarlyView.
A mitochondria‐targeted cationic nanoscale metal organic framework shows strong radiotherapy‐radiodynamic therapy effects and selectively releases digitonin in acidic tumor microenvironments to induce disulfidptosis of cancer cells and downregulate immune checkpoints in cancer and T cells, thereby eliciting strong antitumor immunity to effectively ...
Wenyao Zhen   +7 more
wiley   +1 more source

No evidence of histology subtype-specific prognostic signatures among lung adenocarcinoma and squamous cell carcinoma patients at early stages [PDF]

open access: yesarXiv, 2014
Background Non-small cell lung cancer (NSCLC) is the predominant histological type of lung cancer, accounting for up to 85% of cases. Disease stage is commonly used to determine adjuvant treatment eligibility of NSCLC patients, however, it is an imprecise predictor of the prognosis of an individual patient.
arxiv  

T-zone histiocytes in adenocarcinoma of the lung in relation to postoperative prognosis [PDF]

open access: bronze, 1985
T Furukawa   +5 more
openalex   +1 more source

Rational Design of Metal–Organic Frameworks for Pancreatic Cancer Therapy: from Machine Learning Screening to In Vivo Efficacy

open access: yesAdvanced Materials, EarlyView.
This work explores the MOF landscape to select a single, optimal candidate for successfully delivering cancer drugs (gemcitabine, paclitaxel, SN‐38) into tough pancreatic tumors. Machine learning and simulations guide this search, demonstrating colloidal stability, excellent biocompatibility, cellular uptake, and sustained release.
Francesca Melle   +9 more
wiley   +1 more source

A phase II study of neoadjuvant capecitabine, oxaliplatin, and irinotecan (XELOXIRI) in patients with locally advanced rectal cancer

open access: yesAnnals of Gastroenterological Surgery, Volume 7, Issue 1, Page 81-90, January 2023., 2023
XELOXIRI neoadjuvant chemotherapy appears to be feasible and efficacious for patients with LARC. Although neoadjuvant XELOXIRI alone did not yield our expected pCR rate, the local recurrence rate, 3‐year DFS and measures of safety met current standards.
Chu Matsuda   +16 more
wiley   +1 more source

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