Results 171 to 180 of about 2,251,685 (405)

Absence of an embryonic stem cell DNA methylation signature in human cancer. [PDF]

, 2019
BackgroundDifferentiated cells that arise from stem cells in early development contain DNA methylation features that provide a memory trace of their fetal cell origin (FCO). The FCO signature was developed to estimate the proportion of cells in a mixture
Christensen, Brock C, Kelsey, Karl T, Koestler, Devin C, Salas, Lucas A, Wiencke, John K, Zhang, Ze   +5 more
core  

Engineered Microfluidic Organoid Systems: New Paradigms for Menopause Mechanism Research and Personalized Medicine

Advanced Materials Technologies, EarlyView.
This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang, He Huang, Hongliang Dong, Qiang Ma, Hongyan Jin   +4 more
wiley   +1 more source

397PD KRAS mutation-induced upregulation of PD-L1 mediates immune escape in lung adenocarcinoma [PDF]

, 2016
Shaodong Hong, not provided and Wenbiao Chen, W. Fang, Jun Zhan, L. Zhang   +4 more
openalex   +1 more source

Deciphering N⁶‐Methyladenosine‐Related Genes Signature to Predict Survival in Lung Adenocarcinoma [PDF]

, 2020
Jie Zhu, Min Wang, Daixing Hu
openalex   +1 more source

The Pro-Survival Oct4/Stat1/Mcl-1 Axis Is Associated with Poor Prognosis in Lung Adenocarcinoma Patients [PDF]

, 2021
Yu-Chu Su, Yi-Cheng Chen, Yau‐Lin Tseng, Gia-Shing Shieh, Pensée Wu, Ai‐Li Shiau, Chao‐Liang Wu   +6 more
openalex   +1 more source

AI‐Powered Framework for Evaluating Drug Efficacy for Three‐Dimensional In Vitro Cancer Models in Robot‐Assisted Production

Advanced Robotics Research, EarlyView.
An AI‐powered, robot‐assisted framework automatically produces, images, and analyzes 3D tumor spheroids to evaluate drug efficacy. Integrated modules handle spheroid formation, live/dead staining, brightfield imaging, and automated image analysis, including spheroid segmentation, viability and metrics to assess the drug treatment efficacy. The workflow
Dalia Mahdy, Jesus Nieves, Lukas Königer, Matthias Peindl, Fabio Erhard, Marc Möllmann, Anke Klingner, Markus Münig, Bibin Babu, Thomas Schwarz, Marco Metzger, Gudrun Dandekar, Maximiliane Wußmann, Jan Hansmann   +13 more
wiley   +1 more source

Identification of lung adenocarcinoma-specific exosome RNAs in peripheral blood by RNA-Seq analysis.

, 2020
Liu Xq, Amanda Tufman, Rosemarie Kiefl, Li Gf, Ma Ql, Huber Rm   +5 more
openalex   +2 more sources

CT Radiomics Combined With Clinicopathological Features to Predict Invasive Mucinous Adenocarcinoma in Patients With Lung Adenocarcinoma [PDF]

, 2023
Junjie Zhang, Ligang Hao, Min Li, Xu Qian, Gaofeng Shi   +4 more
openalex   +1 more source

Lung Adenocarcinoma [PDF]

Mayo Clinic Proceedings, 2018
openaire   +2 more sources

Phase‐Separation of YAP Mediates AJUBA Super Enhancer Activation to Promote Aberrant Mitosis in Breast Cancer

Advanced Science, EarlyView.
YAP undergoes phase separation to activate the AJUBA super‐enhancer, driving aberrant mitosis through spindle checkpoint dysregulation in breast cancer. This study uncovers a mechanistic link between YAP condensates, super‐enhancer activation, and aneuploidy formation.
Rui Zhang, Qingwen Huang, Zhuo Chen, Weijian Meng, Hongliang Dong, Zhihong Qi, Liang Liu, Jie Shen, Daxing Xie   +8 more
wiley   +1 more source