Results 191 to 200 of about 273,871 (338)

Distinct CTC Specific RNA Profile Enables NSCLC Early Detection and Dynamic Monitoring of Advanced NSCLC

open access: yesAdvanced Science, EarlyView.
A quantitative CTC RNA assay is developed by incorporating multi‐antibody‐based CTC isolation and specific mRNA quantification using RT‐ddPCR. The NSCLC CTC ScoreD demonstrates high accuracy for early‐stage NSCLC detection, significantly outperforming serum CEA. NSCLC CTC ScoreM exhibits a more accurate early‐warning of responses to different therapies
Xiaoyu Wang   +14 more
wiley   +1 more source

Current updates of CRISPR/Cas9‐mediated genome editing and targeting within tumor cells: an innovative strategy of cancer management

open access: yesCancer Communications, Volume 42, Issue 12, Page 1257-1287, December 2022., 2022
Abstract Clustered regularly interspaced short palindromic repeats‐associated protein (CRISPR/Cas9), an adaptive microbial immune system, has been exploited as a robust, accurate, efficient and programmable method for genome targeting and editing. This innovative and revolutionary technique can play a significant role in animal modeling, in vivo genome
Khaled S. Allemailem   +6 more
wiley   +1 more source

Investigation of sphingolipid-related genes in lung adenocarcinoma. [PDF]

open access: yesFront Mol Biosci
Mao J   +6 more
europepmc   +1 more source

A Case of CA19-9 Producing Papillary Adenocarcinoma (Bronchiolo-Alveolar Carcinoma) of the Lung Diagnosed by Open Lung Biopsy.

open access: bronze, 1994
小牟田 清   +9 more
openalex   +2 more sources

Prognostic value of loss of heterozygosity and KRAS2 mutations in lung adenocarcinoma [PDF]

open access: bronze, 1998
Laura De Gregorio   +6 more
openalex   +1 more source

STING Agonists and How to Reach Their Full Potential in Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
STING agonists show promise in preclinical studies in boosting an anti‐tumor response using the immune system. However, different limitations remain, and future research is needed to better understand how STING activation impacts the tumor microenvironment, identify effective combination strategies, and determine the best tumor types for STING agonist ...
Laura Gehrcken   +3 more
wiley   +1 more source

Genomic characterization reveals distinct mutation landscapes and therapeutic implications in neuroendocrine carcinomas of the gastrointestinal tract

open access: yesCancer Communications, Volume 42, Issue 12, Page 1367-1386, December 2022., 2022
Abstract Background Neuroendocrine carcinomas of the gastrointestinal tract (GI‐NECs) remain a disease of grim prognosis with limited therapeutic options. Their molecular characteristics are still undefined. This study aimed to explore the underlying genetic basis and heterogeneity of GI‐NECs.
Huanwen Wu   +13 more
wiley   +1 more source

Association between Smoking and Tumor Progression in Japanese Women with Adenocarcinoma of the Lung [PDF]

open access: green, 1999
Ikuo Sekine   +7 more
openalex   +1 more source

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