Results 211 to 220 of about 2,251,685 (405)
Geospatial immune variability illuminates differential evolution of lung adenocarcinoma
Nature Medicine, 2020 K. AbdulJabbar, S. Raza, R. Rosenthal, M. Jamal-Hanjani, S. Veeriah, A. Akarca, T. Lund, D. Moore, R. Salgado, M. Al Bakir, L. Zapata, C. Hiley, L. Officer, M. Sereno, C. Smith, S. Loi, A. Hackshaw, T. Marafioti, S. Quezada, N. Mcgranahan, J. Le Quesne, Charles Mariam John Allan Sergio A. Nicholas Rachel Crispi Swanton Jamal-Hanjani Le Quesne Hackshaw Quezada M, C. Swanton, J. Le Quesne, S. Quezada, N. Mcgranahan, Maise Al Bakir, Y. Ngai, A. Sharp, Cristina Rodrigues, O. Pressey, Sean Smith, N. Gower, H. Dhanda, Joan Riley, L. Primrose, L. Martinson, N. Carey, J. Shaw, D. Fennell, G. Wilson, Nicolai J. Birkbak, T. Watkins, M. Escudero, A. Stewart, A. Rowan, J. Goldman, P. van Loo, R. Stone, Tamara Denner, E. Nye, S. Ward, E. Lim, S. Boeing, M. Greco, K. Litchfield, J. Nicod, C. Puttick, Katey S. S. Enfield, Emma C. Colliver, B. Campbell, C. Abbosh, Yin Wu, M. Skrzypski, R. Hynds, A. Georgiou, M. W. Sunderland, J. Reading, K. Peggs, J. Hartley, Pat Gorman, H. Lowe, L. Ensell, V. Spanswick, Angeliki Karamani, D. Biswas, Maryam Razaq, Stephan Beck, A. Huebner, M. Dietzen, C. Naceur-Lombardelli, M. Akther, Haoran Zhai, Nnennaya Kannu, Elizabeth Manzano, S. Bola, E. Ghorani, M. R. de Massy, Elena Hoxha, E. Hatipoglu, Stephanie Ogwuru, B. Chain, Gillian Price, S. Dubois-Marshall, K. Kerr, Shirley Palmer, Heather Cheyne, Joy Miller, K. Buchan, M. Chetty, Mohammed Khalil, V. Ezhil, V. Prakash, G. Anand, Sajid Khan, K. Lau, M. Sheaff, Peter D. Schmid, L. Lim, J. Conibear, R. Schwarz, J. Tugwood, J. Pierce, C. Dive, G. Brady, D. Rothwell, Francesca Chemi, E. Kilgour, F. Blackhall, L. Priest, M. Krebs, P. Crosbie, A. Nakas, S. Rathinam, Louise Nelson, K. Ryanna, Mohamad Tuffail, A. Bajaj, J. Brožík, Fiona Morgan, M. Kornaszewska, R. Attanoos, Haydn Adams, H. Davies, M. Carter, C. Lindsay, F. Gomes, Z. Szallasi, I. Csabai, M. Dióssy, H. Aerts, A. Kirk, M. Asif, J. Butler, Rocco Bilanca, N. Kostoulas, M. Mackenzie, M. Wilcox, S. Busacca, A. Dawson, Mark R. Lovett, M. Shackcloth, Sarah L. Feeney, Julius Asante-Siaw, J. Gosney, Angela E. Leek, Nicola Totten, Jack Davies Hodgkinson, Rachael Waddington, J. Rogan, K. Moore, W. Monteiro, H. Marshall, K. Blyth, C. Dick, A. Kidd, Eric Lim, Paulo De Sousa, S. Jordan, A. Rice, H. Raubenheimer, H. Bhayani, Morag Hamilton, L. Ambrose, A. Devaraj, Hema Chavan, S. Begum, A. Mani, Daniel Kaniu, Mpho Malima, S. Booth, A. Nicholson, Nádia Fernandes, Jessica E. Wallen, P. Shah, S. Danson, J. Bury, J. Edwards, Jennifer Hill, S. Matthews, Yota Kitsanta, J. Rao, S. Tenconi, L. Socci, K. Suvarna, F. Kibutu, P. Fisher, R. Young, Joanne Barker, Fiona G. Taylor, K. Lloyd, T. Light, T. Horey, D. Papadatos-Pastos, P. Russell, S. Lock, Kayleigh Gilbert, David S. Lawrence, M. Hayward, N. Panagiotopoulos, Robert S George, D. Patrini, M. Falzon, E. Borg, Reena Khiroya, Asia Ahmed, Magali N. Taylor, Junaid Choudhary, P. Shaw, S. Janes, Martin D. Forster, T. Ahmad, S. Lee, Javier Herrero, D. Carnell, R. Mendes, J. George, N. Navani, M. Scarci, E. Bertoja, R. Stephens, Emilie Martinoni Hoogenboom, James W. Holding, S. Bandula, B. Naidu, G. Langman, Andrew Robinson, H. Bancroft, A. Kerr, S. Kadiri, C. Ferris, G. Middleton, M. Djearaman, Akshay J. Patel, C. Ottensmeier, S. Chee, Benjamin Johnson, A. Alzetani, E. Shaw, Jason Lester, Y. Summers, R. Califano, Paul Taylor, R. Shah, P. Krysiak, K. Rammohan, E. Fontaine, R. Booton, M. Evison, Stuart Moss, Juliette Novasio, L. Joseph, P. Bishop, A. Chaturvedi, H. Doran, F. Granato, Vijay Joshi, E. Smith, A. Montero, C. Swanton, Yinyin Yuan +270 moresemanticscholar +1 more sourceTargeting NRP1 in Endothelial Cells Facilitates the Normalization of Scar Vessels and Prevents Fibrotic Scarring
Advanced Science, EarlyView.Scars exhibit vascular abnormal alterations, including upregulated NRP1 expression in endothelial cells, increased vascular density and branching, compromised vessel wall integrity, and incomplete pericyte coverage. Therapeutic targeting of NRP1 through hydrogel spray delivery offers a promising approach to normalize aberrant vasculature and prevent ...Yu Wang, Xin Zhou, Min Liu, Meimei Huang, Peirong Chen, Xinying Li, Fangchao Xue, Wenyan Zhao, Di Liu, Lang Li, Yuangang Lu, Wen Zeng +11 morewiley +1 more sourceA Mussel‐Inspired Bioadhesive Patch to Selectively Kill Glioblastoma Cells
Advanced Science, EarlyView.An innovative mussel‐inspired bioadhesive patch has been developed for post‐surgical glioblastoma treatment. The patch, which adheres strongly in biological environments, releases a localized treatment. This treatment, acting via reactive oxygen species, shows specific toxicity to glioblastoma cells.Jose Bolaños‐Cardet, Sara Pugliese, Jordi Bruna, Daniel Ruiz‐Molina, Salvio Suárez‐García, Victor J. Yuste +5 morewiley +1 more sourceSurvival Rates of Adenocarcinoma of the Lung According to Histological Subtype and the Grade of Morphological Differentiation in Resected Cases
, 1979 Shoji Hattori, Harumichi Ikegami, Ryuhei Tateishi, Yoshihiro Hayata, H Funatsu, Mitsuo Oota, T. Yoneyama, Yukío Shimosato, Kunihisa Hashimoto, M Nishimura, Motohiko Ito, Kunio Murakami, Kazuo Saotome, Masahiro Sato, Kenji Sawamura +14 moreopenalex +2 more sourcesACSL5 Regulates Glucose Metabolism and Chemotherapy Sensitivity in Colorectal Cancer Cells under Glutamine Deficiency
Advanced Science, EarlyView.Glutamine deprivation triggers ACSL5 upregulation in tumor cells, sustaining their viability via dual metabolic rewiring programs. ACSL5 enhances glycolysis by relieving p53's inhibition of PGAM1 while also sustaining mitochondrial respiration and TCA cycle flux through promoting IDH2 dimerization.Shuai Tian, Qiaoxia Zhang, Xuedan Sun, Rick Francis Thorne, Zeyuan Shi, Qiang Ji, Zhangran Sun, Yuanxiang Lu, Qun Zhao, Xianjun Yu, Wanglai Hu, Mian Wu +11 morewiley +1 more sourceCharacterizing Stage‐Specific Cellular Dynamics and Microenvironmental Remodeling in Lung Adenocarcinoma by Single‐Cell RNA Sequencing
Advanced Science, EarlyView.This study integrated early‐stage patient specimens with publicly available datasets encompassing non‐malignant lung tissues and advanced‐stage LUAD through single‐cell sequencing, revealing a dynamically remodeled tumor microenvironment characterized by a hypoxia‐adapted malignant subset (C5), immunosuppressive LGMN+ macrophages, STAT1‐driven ...Bomiao Qing, Xiaolan Li, Xiang He, Junyi Wang, Yi Yang, Manling Jiang, Bingbing Yan, Lei Zhang, Anying Xiong, Qin Ran, Guoping Li +10 morewiley +1 more sourceLMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1
Advanced Science, EarlyView.LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...Mengkai Li, Tao Wang, Yuwen Zhong, Zhiming Wang, Wei Li, Zejian Wang, Xinyi Yang, Yu Qiao, Jianfeng Xiang, Wei Gu, Zishu Wang, Lei Sun, Feng Qian +12 morewiley +1 more sourceBiological and clinical significance of the glypican-3 gene in human lung adenocarcinoma: An in silico analysis
, 2023 Raihan Rahman Imon, Sharmin Aktar, Niaz Morshed, Suza Mohammad Nur, Rumana Mahtarin, Farazi Abinash Rahman, Md. Enamul Kabir Talukder, Rahat Alam, Tomasz M. Karpiński, Foysal Ahammad, Mazin A. Zamzami, Shing Cheng Tan +11 moreopenalex +1 more source
