Results 211 to 220 of about 279,339 (314)
Mutations and Reduced Expression of the Transforming Growth Factor‐β Receptor II Gene in Rat Lung Adenocarcinomas Induced by N‐Nitrosobis‐(2‐hydroxypropyl)amine [PDF]
Toshifumi Tsujiuchi+3 more
openalex +1 more source
EVs and EV‐microRNAs (miRNAs) mediate PDAC‐skeletal muscle communication. miR‐223‐5p reduces METTL14 transcription by targeting MAFA, which subsequently decreases m6A methylation in skeletal muscles, ultimately leading to muscle wasting. This study highlights the absorption of miRNA in PDAC‐derived EVs by skeletal muscles and reveals a previously ...
Kangjing Xu+7 more
wiley +1 more source
A lactate related signature for predicting prognosis and tumor microenvironment in lung adenocarcinoma. [PDF]
Wang Y, Li H, Chen C, Yu H, Xu L.
europepmc +1 more source
KRAS/ABHD17C/ALOX15B Axis Promotes Pancreatic Cancer Progression via Ferroptosis Evasion
Phosphorylation of ABHD17C induced by KRASmut/ERK signaling facilitates ALOX15B depalmitoylation and degradation via the CUL4/DDB1/DCAF10 complex, thereby enabling KRASmut‐PDAC cell to evade ferroptosis. Methyl protodioscin inhibits KRASmut‐PDAC progression by disrupting the ABHD17C/ALOX15B interaction and inducing ferroptosis, which represents a ...
Man Li+12 more
wiley +1 more source
Paraneoplastic LGI1 Encephalitis Associated with Lung Adenocarcinoma: A Case Report. [PDF]
Rossato F+5 more
europepmc +1 more source
Upregulated glycosyltransferase GALNT9 in neuroendocrine (NE) carcinomas increases O‐GalNAc glycosylation on cell membrane proteins, particularly Annexin‐A2 (ANXA2). Elevated O‐GalNAc glycan induces the binding of NE cancer cells to mannose binding lectin 2 (MBL2), activating the MBL‐MBL associated serine protease (MBL‐MASP) complement pathway in the ...
Xinyu Chen+24 more
wiley +1 more source
Upregulated Expression of SHMT2 Predicts Poor Survival of Lung Adenocarcinoma. [PDF]
Guo Q, Huang GH, Chen P, Guo C.
europepmc +1 more source