Results 111 to 120 of about 1,371,111 (294)

Dual‐Target Nectin‐4/FAP Heterobivalent Probe 68Ga/177Lu‐FZ‐NF‐1 for Triple‐Negative Breast Cancer: Preclinical Theranostic Evaluation and First‐in‐Human Translation

open access: yesAdvanced Science, EarlyView.
A novel hetero‐bivalent agent, 68Ga/177Lu‐FZ‐NF‐1, concurrently targets Nectin‐4 and FAP in triple‐negative breast cancer. It yields significant preclinical tumor regression and clinically identifies additional metastatic lesions missed by 18F‐FDG PET, demonstrating promising theranostic potential for personalized management.
Ye Li   +13 more
wiley   +1 more source

Quantitative computed tomography detects interstitial lung disease proven by biopsy

open access: yes, 2018
Background: The Quantitative chest CT (QCT) is emerging as a promising tool in the assessment of interstitial lung disease (ILD). However, the precise relationship between QCT parameters and the fibrosis detectable in lung tissue, remains to be ...
Daffré Elisa   +8 more
core  

Usefulness of melanoma antigen (MAGE) gene analysis in tissue samples from percutaneous needle aspiration biopsy of suspected lung cancer lesions

open access: yes, 2010
BACKGROUND: As mortality from lung cancer is still very high, early detection prior to metastasis is important in clinical settings. We prospectively evaluated the clinical usefulness of a reverse transcription-nested polymerase chain reaction (RT-nested
김태훈   +12 more
core   +1 more source

Rapid‐Forming Conductive Antifouling Hydrogel Coating Enables Magnetically Guided Electrochemical POCT for Direct at‑Home Blood Testing

open access: yesAdvanced Science, EarlyView.
The SPG‐MpECis electrochemical POCT platform developed in this study enables direct detection of biomarkers in complex biological samples such as serum and fingerstick blood, demonstrating high concordance with results from clinical reference methods and holding broad potential for at‐home testing applications.
Menghan Li   +10 more
wiley   +1 more source

A General High‐Throughput Mucus Microrheology Platform for Quantitative and Scalable Mucus Phenotyping

open access: yesAdvanced Science, EarlyView.
High‐throughput Differential Dynamic Microscopy measures frequency‐resolved mechanical fingerprints from 3 to 10 μL$\umu{\rm L}$ mucus samples using only a few minutes of operator attention per sample. This automated analysis enables scalable mucus phenotyping for translational research by distinguishing mechanical heterogeneity among donors, disease ...
Feng Ling   +18 more
wiley   +1 more source

Mindfulness for Lung Biopsy

open access: yes
Background: Lung cancer diagnosis causes significant psychological distress. Patient educationand digital health interventions have mitigated anxiety and stress in various clinical settings; the impact of app-based mindfulness intervention on patients ...
MAGANA, ESPERANZA
core   +1 more source

Bronchial washing yield before and after forceps biopsy in patients with endoscopically visible lung cancers

open access: yes, 2007
BACKGROUND AND OBJECTIVE: The need for routine use of bronchial washing in addition to forceps biopsy has been debated in the diagnosis of endoscopically visible lung tumours.
Shim, Young-Soo   +21 more
core   +1 more source

A Tumor‐Boundary Niche Enriched for PD‐1+CD8+T Cells and BTLA+B Cells Drives Resistance to Immunotherapy in NSCLC

open access: yesAdvanced Science, EarlyView.
A spatial niche composed of BTLA+B cells and CD8+T cells is enriched at the tumor boundary in non‐small cell lung cancer. Within this specialized niche, BTLA+B cells act as a dominant source of IL‐6, upregulating PD‐1 on CD8+T cells via STAT3 signaling.
Jiajuan Wu   +6 more
wiley   +1 more source

Risk and benefits of surveillance transbronchial biopsy after lung transplantation: a single center experience

open access: yes, 2018
Acute rejection (including minimal grade A1) is a potential risk factor associated with chronic rejection. Although surveillance transbronchial biopsy (TBBs) are routinely offered to lung recipients in most centres, a favourable effect on survival and ...
S. Sarzana   +8 more
core   +1 more source

Clinical utility of lung biopsy in fibrotic interstitial lung disease

open access: yes
Lung biopsy has traditionally played a fundamental role in addressing diagnostic uncertainty and guiding management of fibrotic interstitial lung disease (fILD).
Chung, Jonathan H   +27 more
core  

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