Results 121 to 130 of about 5,690,964 (274)

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Factors modulating 99mTc‐MAA planar lung dosimetry for 90Y radioembolization

Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose To investigate the accuracy and biases of predicted lung shunt fraction (LSF) and lung dose (LD) calculations via 99mTc‐macro‐aggregated albumin (99mTc‐MAA) planar imaging for treatment planning of 90Y‐microsphere radioembolization.
Benjamin P. Lopez, Armeen Mahvash, James P. Long, Marnix G. E. H. Lam, S. Cheenu Kappadath   +4 more
wiley   +1 more source

Cumulative smoking dose affects the clinical outcomes of EGFR-mutated lung adenocarcinoma patients treated with EGFR-TKIs: a retrospective study

BMC Cancer, 2018
Background Although lung adenocarcinoma with activating epidermal growth factor receptor (EGFR) mutations is common in never smokers, one-third of the patients are ever-smokers.
In Ae Kim, Jong Sik Lee, Hee Joung Kim, Wan Seop Kim, Kye Young Lee   +4 more
doaj   +1 more source

Improving Lung Cancer Diagnosis and Survival Prediction with Deep Learning and CT Imaging [PDF]

arXiv
Lung cancer is a major cause of cancer-related deaths, and early diagnosis and treatment are crucial for improving patients' survival outcomes. In this paper, we propose to employ convolutional neural networks to model the non-linear relationship between the risk of lung cancer and the lungs' morphology revealed in the CT images.
arxiv  

Cancer of the Lung in Iceland [PDF]

, 1959
Gísli Fr. Petersen
openalex   +1 more source

Neoadjuvant PD‐1 Blockade in Resectable Lung Cancer

New England Journal of Medicine, 2018
BACKGROUND Antibodies that block programmed death 1 (PD‐1) protein improve survival in patients with advanced non–small‐cell lung cancer (NSCLC) but have not been tested in resectable NSCLC, a condition in which little progress has been made during the ...
P. Forde, J. Chaft, Kellie N. Smith, V. Anagnostou, T. Cottrell, M. Hellmann, M. Zahurak, Stephen C. Yang, David R. Jones, S. Broderick, R. Battafarano, M. Velez, N. Rekhtman, Zachary T. Olah, J. Naidoo, K. Marrone, Franco Verde, Haidan Guo, Jiajia Zhang, J. Caushi, H. Chan, John-William Sidhom, R. Scharpf, J. White, E. Gabrielson, Hao Wang, G. Rosner, V. Rusch, J. Wolchok, T. Merghoub, J. Taube, V. Velculescu, S. Topalian, J. Brahmer, D. Pardoll   +34 more
semanticscholar   +1 more source

CircCCNB1 inhibits vasculogenic mimicry by sequestering NF90 to promote miR‐15b‐5p and miR‐7‐1‐3p processing in nasopharyngeal carcinoma

Molecular Oncology, EarlyView.
CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan, Fenghua Tan, Jie Wu, Zhaoyang Zeng, Wenjia Guo, He Huang, Wei Xiong   +6 more
wiley   +1 more source

Feasibility of radical cardiac‐sparing, treatment planning strategies for patients with locally advanced, non‐small cell lung cancer

Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose A set of treatment planning strategies were designed and retrospectively implemented for locally advanced, non‐small cell lung cancer (NSCLC) patients in order to minimize cardiac dose without compromising target coverage goals. Methods Retrospective analysis was performed for 20 NSCLC patients prescribed to 60–66 Gy that received a ...
Joshua P. Kim, Jake Dewalt, Aharon Feldman, Khaled Adil, Benjamin Movsas, Indrin J. Chetty   +5 more
wiley   +1 more source

Cancer mortality projection: disparities, COVID-19, and late diagnosis impact [PDF]

arXiv
This paper investigates projection of two major causes of cancer mortality, breast cancer and lung cancer, by using a Bayesian modelling framework. We investigate patterns in 2001-2018 (as baseline) in cause-specific cancer mortality and project these by year of death and various risk factors: age, gender, regions of England, income deprivation ...
arxiv  

Lung Cancer Mortality and the Length of Cigarette Ends [PDF]

, 1959
Richard E. Doll, A. B. Hill, Percy G. Gray, Elizabeth A. Parr   +3 more
openalex   +1 more source