Results 31 to 40 of about 7,594,057 (369)

RRx-001 in Refractory Small-Cell Lung Carcinoma: A Case Report of a Partial Response after a Third Reintroduction of Platinum Doublets. [PDF]

, 2016
RRx-001 is a pan-active, systemically nontoxic epigenetic inhibitor under investigation in advanced non-small cell lung cancer, small-cell lung cancer and high-grade neuroendocrine tumors in a Phase II clinical trial entitled TRIPLE THREAT (NCT02489903),
Brzezniak, Christina, Cabrales, Pedro, Caroen, Scott Z, Carter, Corey A, Degesys, Aiste, Kim, Michelle M, Lybeck, Harry, Oronsky, Arnold L, Oronsky, Bryan T, Oronsky, Neil, Reid, Tony, Roswarski, Joseph, Scicinski, Jan J   +12 more
core   +3 more sources

NCCN Guidelines Insights: Non-Small Cell Lung Cancer, Version 2.2021.

The Journal of the National Comprehensive Cancer Network, 2021
The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Non-Small Cell Lung Cancer (NSCLC) address all aspects of management for NSCLC.
D. Ettinger, D. Wood, D. Aisner, W. Akerley, J. Bauman, A. Bharat, D. Bruno, Joe Y. Chang, L. Chirieac, T. D’amico, T. Dilling, J. Dowell, S. Gettinger, M. Gubens, A. Hegde, M. Hennon, R. Lackner, M. Lanuti, T. Leal, Jules Lin, B. Loo, C. Lovly, R. Martins, E. Massarelli, D. Morgensztern, T. Ng, G. Otterson, S. Patel, Gregory Riely, S. Schild, T. Shapiro, Aditi P. Singh, J. Stevenson, A. Tam, J. Yanagawa, Stephen C. Yang, K. Gregory, M. Hughes   +37 more
semanticscholar   +1 more source

PD‐0332991 combined with cisplatin inhibits nonsmall cell lung cancer and reversal of cisplatin resistance

Thoracic Cancer, 2021
Background: Acquired resistance of chemotherapy, especially cisplatin, is a major challenge in lung cancer treatment. We conducted this study to examine whether a cyclin D kinase 4/6 (CDK4/6) inhibitor, PD 0332991, could reverse cisplatin resistance in ...
Minghui Liu, Liyuan Cui, Xin Li, Chunqiu Xia, Yongwen Li, Rui Wang, Fan Ren, Hongyu Liu, Jun Chen   +8 more
doaj   +1 more source

EML4-ALK-mediated activation of the JAK2-STAT pathway is critical for non-small cell lung cancer transformation

BMC Pulmonary Medicine, 2021
Background The echinoderm microtubule-associated protein-like-4 anaplastic lymphoma kinase (EML4-ALK) fusion gene was identified in a subset of non-small cell lung cancer (NSCLC) patients. They responded positively to ALK inhibitors.
Ying Li, Yongwen Li, Hongbing Zhang, Ruifeng Shi, Zihe Zhang, Hongyu Liu, Jun Chen   +6 more
doaj   +1 more source

Effect of Upper Arm Position Changes on the Occurrence of Ipsilateral Shoulder Pain After Single-Operator Port Thoracoscopy

Frontiers in Surgery, 2022
BackgroundThe aim of this study was to explore the factors associated with the occurrence of ISP after VATS to reduce the incidence of ISP and improve patients' quality of life.MethodsThe data of patients were collected between June 2020 and August 2020 ...
Dian Ren, Bo Zhang, Jie Xu, Renwang Liu, Jing Wang, Huandong Huo, Hao Zhang, Jingtong Zeng, Hanqing Wang, Xiaohong Xu, Mei Lin, Song Xu, Song Xu, Zuoqing Song, Zuoqing Song   +14 more
doaj   +1 more source

Pembrolizumab plus Chemotherapy for Squamous Non–Small‐Cell Lung Cancer

New England Journal of Medicine, 2018
Background Standard first‐line therapy for metastatic, squamous non–small‐cell lung cancer (NSCLC) is platinum‐based chemotherapy or pembrolizumab (for patients with programmed death ligand 1 [PD‐L1] expression on ≥50% of tumor cells).
L. Paz-Ares, A. Luft, D. Vicente, A. Tafreshi, M. Gümüş, J. Mazières, B. Hermes, F. Senler, T. Csőszi, A. Fülöp, J. Rodríguez-Cid, Jonathan Wilson, S. Sugawara, T. Kato, K. Lee, Ying Cheng, S. Novello, B. Halmos, Xiaodong Li, G. Lubiniecki, B. Piperdi, D. Kowalski   +21 more
semanticscholar   +1 more source

Radiation-induced lung damage promotes breast cancer lung-metastasis through CXCR4 signaling [PDF]

, 2015
Radiotherapy is a mainstay in the postoperative treatment of breast cancer as it reduces the risks of local recurrence and mortality after both conservative surgery and mastectomy.
Bracke, Marc, De Wagter, Carlos, De Wever, Olivier, Descamps, Benedicte, Feys, Lynn, Vanhove, Christian, Veldeman, Liv, Vermeulen, Stefan, Vral, Anne   +8 more
core   +3 more sources

Characteristics and outcome of patients with newly diagnosed advanced or metastatic lung cancer admitted to intensive care units (ICUs) [PDF]

, 2018
BACKGROUND: Although patients with advanced or metastatic lung cancer have poor prognosis, admission to the ICU for management of life-threatening complications has increased over the years.
A Steven, A-C Barbot, A-C Toffart, AK Adam, C Hamard, CA Reichner, CG Slatore, DV Schapira, E Azoulay, E Azoulay, E Biskup, F Vincent, FS Taccone, JI Salluh, JL Vincent, JR Gall Le, K Puxty, M Früh, M Garrouste-Orgeas, M Maltoni, M Soares, M Soares, M Soares, ME Charlson, MM Oken, MR Bonomi, P Zarogoulidis, R Fisher, RR Jennens, S Anisoglou, S Roques, T Cooksley, T Tanvetyanon, X Nan, Y Zerbib, Y-F Chen, YJ Kim   +36 more
core   +2 more sources

Primary chondroma of posterior mediastinum with Horner’s syndrome: a case report

World Journal of Surgical Oncology, 2018
Background Chondroma is a slowly growing, benign cartilaginous tumor which predominantly occurs in long bones of the hands and feet. Primary mediastinal chondroma is rare, especially with Horner’s syndrome.
Xiaoqian Xu, Xin Li, Fan Ren, Ming Dong, Minghui Liu, Jun Chen   +5 more
doaj   +1 more source

Cancer statistics, 2023

Ca, 2023
Each year, the American Cancer Society estimates the numbers of new cancer cases and deaths in the United States and compiles the most recent data on population‐based cancer occurrence and outcomes using incidence data collected by central cancer ...
R. Siegel, K. D. Miller, N. S. Wagle, A. Jemal   +3 more
semanticscholar   +1 more source