Results 41 to 50 of about 2,054,545 (287)

Identification of a novel oxidative stress-related prognostic model in lung adenocarcinoma

Frontiers in Pharmacology, 2022
Background: Oxidative stress (OxS) participates in a variety of biological processes, and is considered to be related to the occurrence and progression of many tumors; however, the potential diagnostic value of OxS in lung cancer remains unclear.Methods:
Yifan Zhu, Yifan Zhu, Quanying Tang, Quanying Tang, Weibo Cao, Weibo Cao, Ning Zhou, Ning Zhou, Xin Jin, Xin Jin, Zuoqing Song, Zuoqing Song, Lingling Zu, Lingling Zu, Song Xu, Song Xu   +15 more
doaj   +1 more source

Venous Thromboembolism in Pediatric Bone Sarcoma Patients: A 10‐Year, Single‐Institution Experience Encompassing the COVID‐19 Pandemic

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa, Shou Xu, Mark Zobeck, Sarah E. Sartain, Nino Rainusso, Lisa Wang, Nicole Montgomery, Paige Wheaton, Sarah Whittle   +8 more
wiley   +1 more source

PD‐0332991 combined with cisplatin inhibits nonsmall cell lung cancer and reversal of cisplatin resistance

Thoracic Cancer, 2021
Background: Acquired resistance of chemotherapy, especially cisplatin, is a major challenge in lung cancer treatment. We conducted this study to examine whether a cyclin D kinase 4/6 (CDK4/6) inhibitor, PD 0332991, could reverse cisplatin resistance in ...
Minghui Liu, Liyuan Cui, Xin Li, Chunqiu Xia, Yongwen Li, Rui Wang, Fan Ren, Hongyu Liu, Jun Chen   +8 more
doaj   +1 more source

Polymorphisms of CYP1A1 I462V and GSTM1 genotypes and lung cancer susceptibility in Mongolian [PDF]

, 2009
Aim: To study the genotype of cytochrome P450 1A1(CYP1A1) I462V and glutathions S-transferase M1( GSTM1) and the relationship of the genetic polymorphism of them with the susceptibility of lung cancer in Mongolia of China.
Fuhou Chang, Guang Wang, Jia Ma, Jun QI, Min-jie Wang, Qin Yin, Zhi-Xie Zhang   +6 more
core   +1 more source

Diabetes status and post-load plasma glucose concentration in relation to site-specific cancer mortality: findings from the original Whitehall study [PDF]

, 2004
ObjectiveWhile several studies have reported on the relation of diabetes status with pancreatic cancer risk, the predictive value of this disorder for other malignancies is unclear.
A Czyzyk, A Sasaki, AB Lowenfels, AB Lowenfels, Anon, B Armstrong, B Balkau, BA O?Mara, BA O?Mara, C Vecchia LA, DD Reid, DD Reid, DR Cox, E Breeze, E Freund, E Ohmura, E Tabor, F Vegt de, G Davey Smith, G Davey Smith, G Davey Smith, G Davey Smith, G Davey Smith, G Rose, G. David. Batty, GA Rose, GD Batty, GD Batty, GD Batty, GD Batty, GD Batty, George Davey Smith, H Brenner, HO Adami, HO Adami, II Kessler, II Kessler, J Everhart, J Permert, J Permert, J Schafer, JH Fuller, JH Fuller, JH Fuller, K Steenland, L Gullo, L Wideroff, M Mori, M Ragozzino, Martin J. Shipley, MC Yu, MG Marmot, MG Marmot, MG Marmot, Michael Marmot, N Trinkler, NS Weiss, RJ Jarrett, RJ Jarrett, RZ Stolzenber-Solomon, SAS Institute Inc, SH Saydah, SM Gapstur, SS Coughlin, W Fisher, W Levine, WH Chow, Y Lin   +67 more
core   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

Lymph node metastasis in lung squamous cell carcinoma and identification of metastasis‐related genes based on the Cancer Genome Atlas

Cancer Medicine, 2019
Squamous cell carcinoma (SCC) is a unique clinical and histological category that accounts for about 30% of total lung cancer. To identify risk factors for lymph node metastasis and analyze the molecular features of these metastases in lung SCC, a ...
Ming Dong, Hao Gong, Tong Li, Xin Li, Jinghao Liu, Hongbing Zhang, Minghui Liu, Gang Chen, Hongyu Liu, Jun Chen   +9 more
doaj   +1 more source

STE029 Overcomes EGFR-TKI Resistance in Human Lung Adenocarcinoma

Chinese Journal of Lung Cancer, 2022
Background and objective Acquired and primary resistance to epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) is still the bottleneck of clinical treatment of advanced non-small cell lung cancer (NSCLC).
Lin HUANG, Mei HOU, Jiewei LIU, Yang LI, Wang SHEN, Qinghua ZHOU   +5 more
doaj   +1 more source

Vermonters’ Opinions on Low-Dose CT Lung Cancer Screening [PDF]

, 2015
Introduction: Lung cancer is the number one cause of cancer death among men and women in Vermont and the United States. Smoking increases the risk of lung cancer—nearly 90% of lung cancer is due to smoking.
Albertson, Benjamin, Bennett, Eric, Chiang, Homer, Kaminsky, David, Keller, Erin, Lantz, Katherine, Ma, Melanie, Mallory, Sharon, Ryan, Rebecca   +8 more
core   +1 more source

RRx-001 in Refractory Small-Cell Lung Carcinoma: A Case Report of a Partial Response after a Third Reintroduction of Platinum Doublets. [PDF]

, 2016
RRx-001 is a pan-active, systemically nontoxic epigenetic inhibitor under investigation in advanced non-small cell lung cancer, small-cell lung cancer and high-grade neuroendocrine tumors in a Phase II clinical trial entitled TRIPLE THREAT (NCT02489903),
Brzezniak, Christina, Cabrales, Pedro, Caroen, Scott Z, Carter, Corey A, Degesys, Aiste, Kim, Michelle M, Lybeck, Harry, Oronsky, Arnold L, Oronsky, Bryan T, Oronsky, Neil, Reid, Tony, Roswarski, Joseph, Scicinski, Jan J   +12 more
core   +3 more sources