Results 61 to 70 of about 4,921,476 (300)

Current Status of Self-transcendence among Lung Cancer Patients 
and Its Influencing Factors

Chinese Journal of Lung Cancer
Background and objective Different degrees of self-transcendence exist in lung cancer patients, which can stimulate patients' self-awareness and promote them to face negative events in life positively, thus improving patients' quality of life and ...
Xue YANG, Yu LUO, Lijuan YE, Yingli YU, Daxing ZHU   +4 more
doaj   +1 more source

Expression and Clinical Significance of PD-1 and PD-L1 in Pulmonary Carcinoids

Chinese Journal of Lung Cancer, 2016
Background and objective The incidence of pulmonary carcinoid (PC) is very rare in primary lung malignant tumors, and the prognosis of this disease is closely associated with its pathological features. In this study, the expressions of programmed death 1
Mingbiao LI, Song XU, Haiyang FAN, Hongyi ZHANG, Ying LI, Yongwen LI, Minghui LIU, Hongyu LIU, Jun CHEN   +8 more
doaj   +1 more source

Metastatic sites and survival in lung cancer.

, 2014
Population-based data on metastatic sites and survival in site-specific metastases are lacking for lung cancer and for any cancer because most cancer registries do not record metastases.
Riihimäki, Matias, Thomsen, Hauke, Hemminki, Kari, Sundquist, Jan, Fallah, Mahdi,, Hemminki, A, Sundquist, Jan,, Sundquist, Kristina, Fallah, Mahdi, Hemminki, Kari,, Riihimäki, Matias,, Thomsen, Hauke,, Sundquist, Kristina,, Lund University.   +13 more
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Unlocking biomarker discovery: Large scale application of aptamer proteomic technology for early detection of lung cancer [PDF]

, 2010
Lung cancer is the leading cause of cancer deaths, because ~84% of cases are diagnosed at an advanced stage. Worldwide in 2008, ~1.5 million people were diagnosed and ~1.3 million died – a survival rate unchanged since 1960.
Alex Stewart, Stewart, A, Joel L Weissfeld, William L. Bigbee, Mehan Mike, Rom, William N, Stewart, Alex, Gold Larry, Miller, YE, Edward N. Brody, William N Rom, Weissfeld, JL, Harvey I Pass, Siegfried, JM, Pass Harvey I., Stephen Williams, Siegfried, Jill M, Walker, Jeffrey J, Walker Jeffrey J., Bigbee, William L, William L Bigbee, Pass, Harvey I, Rachel M Ostroff, Ostroff, RM, Weissfeld Joel L., Gold, Larry, Bigbee William L., York E. Miller, Zichi Dom, York E Miller, Weissfeld, Joel L, William N. Rom, Gold, L, Franklin Wilbur, Joel L. Weissfeld, Edward N Brody, Franklin, Wilbur, Williams Stephen, Rom, WN, Miller York E., Jeffrey J Walker, Franklin, W, Zichi, D, Mehan, M, Miller, York E, Harvey I. Pass, Brody, EN, Bigbee, WL, Ostroff, Rachel M, Walker, JJ, Rom William N., Williams, Stephen, Dom Zichi, Stewart Alex, Pass, HI, Mehan, Mike, Wilbur Franklin, Brody Edward N., Siegfried Jill M., Mike Mehan, Williams, S, Zichi, Dom, Jill M Siegfried, Rachel M. Ostroff, Ostroff Rachel M., Jeffrey J. Walker, Jill M. Siegfried, Larry Gold, Brody, Edward N   +68 more
core   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Assessing first-line treatment for advanced EGFR-mutated NSCLC in diverse clinicopathological subgroups: a systematic review and network meta-analysis

BMC Cancer
Background This network meta-analysis (NMA) aimed to indicate the most effective first-line therapeutic options for advanced EGFR-mutated NSCLC, particularly considering their specific clinicopathological characteristics.
Ting Mei, Ting Wang, Qinghua Zhou
doaj   +1 more source

Ensartinib as a neoadjuvant therapy for stage IIIA non-small cell lung cancer patients with EML4-ALK fusion: a case report and literature review

Frontiers in Oncology
Anaplastic lymphoma kinase (ALK) inhibitors have shown efficacy in treating ALK-positive advanced non-small cell lung cancer (NSCLC) patients. However, the effectiveness of ensartinib neoadjuvant therapy remains ambiguous.
Hao Zhang, Hao Zhang, Wei Xia, Wei Xia, Yifan Zhang, Yifan Zhang, Shihao Bao, Shihao Bao, Jingtong Zeng, Jingtong Zeng, Xianjie Li, Xianjie Li, Bo Zhang, Bo Zhang, Hanqing Wang, Hanqing Wang, Song Xu, Song Xu, Zuoqing Song, Zuoqing Song   +19 more
doaj   +1 more source

Metabolic Signatures of Lung Cancer in Biofluids: NMR-Based Metabonomics of Blood Plasma [PDF]

, 2011
In this work, the variations in the metabolic profile of blood plasma from lung cancer patients and healthy controls were investigated through NMR-based metabonomics, to assess the potential of this approach for lung cancer screening and diagnosis.
Joana Carrola, Brian J. Goodfellow, Carreira, Isabel M., Goodfellow, Brian J., Rocha, Cláudia M., Gil, Ana M., Carvalho, Lina, Cláudia M. Rocha, António S. Barros, Lina Carvalho, Barros, António S., Ana Gomes, Bernardo, Joao, Carrola, Joana, Sousa, Vitor, Ana M. Gil, João Bernardo, Vitor Sousa, Gomes, Ana, Iola F. Duarte, Isabel M. Carreira, Duarte, Iola F.   +21 more
core   +1 more source