Results 41 to 50 of about 5,690,964 (274)

PD‐0332991 combined with cisplatin inhibits nonsmall cell lung cancer and reversal of cisplatin resistance

open access: yesThoracic Cancer, 2021
Background: Acquired resistance of chemotherapy, especially cisplatin, is a major challenge in lung cancer treatment. We conducted this study to examine whether a cyclin D kinase 4/6 (CDK4/6) inhibitor, PD 0332991, could reverse cisplatin resistance in ...
Minghui Liu   +8 more
doaj   +1 more source

A retrospective stenting study on superior vena cava syndrome caused by lung cancer

open access: yesThoracic Cancer, 2020
Background Superior vena cava syndrome (SVCS) is a common condition predominantly caused by lung cancer. The presence of symptoms of SVCS, such as elevated intracranial pressure and laryngeal edema, indicates an unfavorable prognosis for lung cancer ...
Sen Wei   +8 more
doaj   +1 more source

Identification of a novel oxidative stress-related prognostic model in lung adenocarcinoma

open access: yesFrontiers in Pharmacology, 2022
Background: Oxidative stress (OxS) participates in a variety of biological processes, and is considered to be related to the occurrence and progression of many tumors; however, the potential diagnostic value of OxS in lung cancer remains unclear.Methods:
Yifan Zhu   +15 more
doaj   +1 more source

Predicting Lung Cancer's Metastats' Locations Using Bioclinical Model [PDF]

open access: yes, 2023
Lung cancer is a leading cause of cancer-related deaths worldwide. The spread of the disease from its primary site to other parts of the lungs, known as metastasis, significantly impacts the course of treatment. Early identification of metastatic lesions is crucial for prompt and effective treatment, but conventional imaging techniques have limitations
arxiv   +1 more source

Lymph node metastasis in lung squamous cell carcinoma and identification of metastasis‐related genes based on the Cancer Genome Atlas

open access: yesCancer Medicine, 2019
Squamous cell carcinoma (SCC) is a unique clinical and histological category that accounts for about 30% of total lung cancer. To identify risk factors for lymph node metastasis and analyze the molecular features of these metastases in lung SCC, a ...
Ming Dong   +9 more
doaj   +1 more source

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

open access: yesFEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan   +10 more
wiley   +1 more source

Zero-Shot and Few-Shot Learning for Lung Cancer Multi-Label Classification using Vision Transformer [PDF]

open access: yesarXiv, 2022
Lung cancer is the leading cause of cancer-related death worldwide. Lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC) are the most common histologic subtypes of non-small-cell lung cancer (NSCLC). Histology is an essential tool for lung cancer diagnosis. Pathologists make classifications according to the dominant subtypes.
arxiv  

Osimertinib or Platinum–Pemetrexed in EGFR T790M–Positive Lung Cancer

open access: yesNew England Journal of Medicine, 2017
BACKGROUND Osimertinib is an epidermal growth factor receptor tyrosine kinase inhibitor (EGFR‐TKI) that is selective for both EGFR‐TKI sensitizing and T790M resistance mutations in patients with non–small‐cell lung cancer.
T. Mok   +16 more
semanticscholar   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Clinical Significance and Next-Generation Sequencing of Chinese Pulmonary Sarcomatoid Carcinoma

open access: yesScientific Reports, 2017
Pulmonary Sarcomatoid Carcinoma (PSC) constitutes a heterogeneous group of non-small-cell lung carcinomas (NSCLCs) with a poor prognosis. In this study, a group of 7 patients with PSC was studied. Microscope analysis of all 7 cases revealed a pleomorphic
Xin Li   +7 more
doaj   +1 more source

Home - About - Disclaimer - Privacy