Results 271 to 280 of about 1,756,909 (330)

Mitochondria‐Targeted Multimodal Nanotherapeutics Suppress Oxidized mtDNA‐Driven Inflammation at the Source

open access: yesAdvanced Science, EarlyView.
Ox‐mtDNA fragments escaping from mitochondria drive robust inflammatory responses. A targeted nanoplatform simultaneously inhibits mitochondrial FEN1‐mediated mtDNA cleavage and scavenges ROS, preventing the generation of immunogenic Ox‐mtDNA fragments. The released SeNPs further promote autophagic clearance of cytosolic mtDNA. Consequently, cGAS‐STING,
Wen‐Ling Li   +7 more
wiley   +1 more source

E-cigarette aerosol deposition efficiency is increased in direct-to-lung, compared to mouth-to-lung, inhalation patterns

open access: hybrid
Marzieh Aghababaie   +4 more
openalex   +1 more source

Solitary nodular pulmonary amyloidosis mimicking primary lung cancer: A case report. [PDF]

open access: yesRadiol Case Rep
Hashimoto R   +3 more
europepmc   +1 more source

PAH-associated health risk from ultrafine particles: an urban field study. [PDF]

open access: yesAir Qual Atmos Health
Su WC, Lee J, Afshar M, Zhang K, Han I.
europepmc   +1 more source
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Lung deposition from four nebulizers

Respiratory Medicine, 1993
The total and regional deposition of aerosol has been compared using four nebulizers; the Pari Boy 37.80, Pari IS-2, RespirGard II and Penta-Sonic. The aerosol was radiolabelled with [99Tcm]DTPA, administered to ten healthy subjects and the distributions monitored by gamma scintigraphy.
J G, Hardy, S P, Newman, M, Knoch
openaire   +2 more sources

Deposition of Aerosols in the Lungs: Particle Characteristics

Journal of Aerosol Medicine and Pulmonary Drug Delivery, 2021
Of the various particle properties that affect deposition in the respiratory tract, particle diameter and particle density are the most commonly considered, since their effect on deposition is well known and important, as has been discussed earlier in this chapter. However, there are several other particle properties that can affect particle deposition
openaire   +2 more sources

The topography of particle deposition in the human lung

Respiration Physiology, 1989
The effect of varying particle size on the site of deposition of inhaled particles in the human lung was measured in 11 young healthy male subjects. The simultaneous inhalation of two chemically inert, radiolabelled particles, differing in size but in no other respect, controlled for all other variables including airways geometry, breathing pattern and
P, Pityn   +4 more
openaire   +2 more sources

Lung aerosol deposition in suckling infants

Archives of Disease in Childhood, 2012
Aerosol therapy in infants may be greatly compromised by face mask rejection due to squirming and crying. Lung aerosol deposition in crying infants may thereby be greatly reduced. Since 'suckling' on a pacifier calms infants, they should more readily accept a face mask that incorporates a pacifier.
Israel, Amirav   +4 more
openaire   +2 more sources

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