Results 281 to 290 of about 1,756,909 (330)

The Deposition of Labeled Aerosols in Lung Disorders

1980
Regional deposition of aerosols in the human lung is affected by conditions that change the characteristics of the bronchial tree. An important question is whether different airway disorders are characterized by specific patterns of regional deposition of labeled aerosols [1–4]. From experimental work on the penetration of aerosols into the airways, it
SANTOLICANDRO A., PALLA, ANTONIO, GIUNTINI, CARLO   +2 more
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TITANIUM DIOXIDE DEPOSITION AND ADENOCARCINOMA OF THE LUNG

Acta Pathologica Japonica, 1986
A case of titanium dioxide pneumoconiosis accompanied by lung cancer is reported. The patient was a fifty‐three‐year‐old male, who was engaged in packing titanium dioxide for about thirteen years. At autopsy, a papillary adenocarcinoma was located in the right lung.
I, Yamadori, S, Ohsumi, K, Taguchi
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Physiological Factors Affecting Lung Deposition

Journal of Aerosol Medicine and Pulmonary Drug Delivery, 2021
Ventilation and mechanics of breathing are an integral part of respiratory physiology that directly affect aerosol transport and deposition in the lung. Although natural breathing pattern varies widely among individuals, breathing pattern is controllable, and by using an appropriate breathing pattern, aerosol deposition can be ...
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Deposition of Inhaled Particles in Human Lungs

Nature, 1966
DURING the past 25 years, six independent groups of workers have measured the decrease in concentration of particles in exhaled air during steady breathing, while their subjects inhaled various aerosols, and have expressed their findings as a relationship between particle size and lung deposition. These results fall into two ranges, three of the groups
C N, Davies, D C, Muir
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Particle deposition in the lung of the Göttingen minipig

Inhalation Toxicology, 2010
We report on particle deposition in the tracheobronchial and pulmonary regions of the respiratory tract of the minipig and its dependence on particle size. Four animals breathing spontaneously via the nose were exposed for 1 h to known concentrations of three different polydisperse dry aerosols composed of bovine serum albumin (BSA) and an oxide of a ...
Horst, Windt, Heiko, Kock, Frank, Runge, Ulrich, Hübel, Wolfgang, Koch   +4 more
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Lung Deposition of Droplet Aerosols in Monkeys

Inhalation Toxicology, 2008
Nonhuman primates are often the animal models of choice to study the infectivity and therapy of inhaled infectious agents. Most animal models for inhaled infectious diseases use aerosol/droplets generated by an atomization technique such as a Collison nebulizer that produces particles in the size range of 1 to 3 microm in diameter.
Y S, Cheng, H, Irshad, P, Kuehl, T D, Holmes, R, Sherwood, C H, Hobbs   +5 more
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Mechanisms of Aerosol Lung Deposition

2021
The mechanism of aerosol delivery, deposition, and absorption is an important factor that controls the process of aerosol delivery and efficacy. Several factors control aerosol particle depositions in the lung, some of these factors depend on the patient itself while other factors are related to the drug formulation and the emitted aerosol particle ...
Mohamed E. A. Abdelrahim, Haitham Saeed, Hadeer S. Harb, Yasmin M. Madney   +3 more
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Deposition of Inhaled Particles in Human Lungs

Nature, 1967
IN a recent communication, Davies and Muir1 pointed out that the experimental results from six independent studies of the retention of particles in the human respiratory system fall into two groups, the results of one group indicating higher values for the deposition than the other.
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Deposition of small particles in the developing lung

Paediatric Respiratory Reviews, 2012
Infancy is a time of marked and rapid changes in respiratory tract development. Infants (0-1 year of age) and young children (1- 3 years of age) are a unique subpopulation with regard to therapeutic aerosols. Anatomical, physiological and emotional factors, peculiar to these age groups, present significant challenges for aerosol delivery to the ...
Israel, Amirav, Michael T, Newhouse
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The Influence of Lung Deposition on Clinical Response

Journal of Aerosol Medicine, 2001
Delivery of more drug to the lung may appear to be a desirable goal in the treatment of asthma and chronic obstructive pulmonary disease, since only 10 to 15% of a drug dose administered via a metered dose inhaler (MDI) reaches the lung. However, increasing the dose of most inhaled drugs may only lead to an increase in side effects, since maximal ...
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