Results 91 to 100 of about 1,346,074 (337)

Primary extranodal diffuse large B‐cell lymphoma: Molecular features, treatment, and prognosis

Aging and Cancer, Volume 3, Issue 3-4, Page 133-146, September-December 2022., 2022
One‐third of DLBCL arises from extranodal organs and is challenging to manage. Molecular features are critical to elucidate the differences in clinical features, predict the disease prognosis, and improve effective targeted therapeutic strategies. Abstract Diffuse large B‐cell lymphoma (DLBCL) is the most common subtype of non‐Hodgkin's lymphoma and ...
Si‐Yuan Chen, Meng‐Meng Ji, Peng‐Peng Xu, Wei‐Li Zhao   +3 more
wiley   +1 more source

A Retrospective Analysis of 2-Year Follow-Up of Patients with Incidental Findings of Sarcoidosis

Diagnostics
Introduction: Sarcoidosis is a multi-system granulomatous disease most commonly involving the lungs. It may be incidentally diagnosed during imaging studies for other conditions or non-specific symptoms.
Oluwabukola Thomas-Orogan, Shaney L. Barratt, Muhammad Zafran, Apollo Kwok, Anneliese Simons, Eoin P. Judge, Matthew Wells, Richard Daly, Charles Sharp, Abiramy Jeyabalan, Martin Plummeridge, Ladli Chandratreya, Lisa G. Spencer, Andrew R. L. Medford, Huzaifa I. Adamali   +14 more
doaj   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

Molecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia, Anouk C. de Jong, Lisanne F. van Dessel, Vanja de Weerd, Corine Beaufort, Jean Helmijr, José Alberto Nakauma‐González, Job van Riet, Paul Hamberg, Daniel Vis, Michiel S. van der Heijden, Nick Beije, Martijn P. Lolkema, Teoman Deger, Saskia M. Wilting, Ronald de Wit, Maurice P. H. M. Jansen, John W. M. Martens   +17 more
wiley   +1 more source

A poroelastic model coupled to a fluid network with applications in lung modelling [PDF]

arXiv, 2014
Here we develop a lung ventilation model, based a continuum poroelastic representation of lung parenchyma and a 0D airway tree flow model. For the poroelastic approximation we design and implement a lowest order stabilised finite element method. This component is strongly coupled to the 0D airway tree model. The framework is applied to a realistic lung
arxiv  

Apolipoprotein B synthesized by Hep G2 cells undergoes fatty acid acylation.

Journal of Lipid Research, 1988
Apolipoprotein B is the principal protein associated with cholesterol transport in the blood and has been proposed to play a central role in human atherogenesis.
J M Hoeg, M S Meng, R Ronan, S J Demosky, Jr, T Fairwell, H B Brewer, Jr   +5 more
doaj  

A comparison of curated gene sets versus transcriptomics-derived gene signatures for detecting pathway activation in immune cells

BMC Bioinformatics, 2020
Background Despite the significant contribution of transcriptomics to the fields of biological and biomedical research, interpreting long lists of significantly differentially expressed genes remains a challenging step in the analysis process.
Bin Liu, Patrick Lindner, Adan Chari Jirmo, Ulrich Maus, Thomas Illig, David S. DeLuca   +5 more
doaj   +1 more source

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

Molecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

Factors modulating 99mTc‐MAA planar lung dosimetry for 90Y radioembolization

Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose To investigate the accuracy and biases of predicted lung shunt fraction (LSF) and lung dose (LD) calculations via 99mTc‐macro‐aggregated albumin (99mTc‐MAA) planar imaging for treatment planning of 90Y‐microsphere radioembolization.
Benjamin P. Lopez, Armeen Mahvash, James P. Long, Marnix G. E. H. Lam, S. Cheenu Kappadath   +4 more
wiley   +1 more source

Deep LF-Net: Semantic Lung Segmentation from Indian Chest Radiographs Including Severely Unhealthy Images [PDF]

arXiv, 2020
A chest radiograph, commonly called chest x-ray (CxR), plays a vital role in the diagnosis of various lung diseases, such as lung cancer, tuberculosis, pneumonia, and many more. Automated segmentation of the lungs is an important step to design a computer-aided diagnostic tool for examination of a CxR.
arxiv  

Initiation of antiretroviral therapy or antiretroviral prophylaxis in pregnant women living with HIV registered in five townships of Mandalay, Myanmar: A cross sectional study

BMC Pregnancy and Childbirth, 2019
Background A series of interventions are required to prevent mother to child transmission (PMTCT) of Human Immunodeficiency Virus (HIV) starting from HIV testing of pregnant women, initiating antiretroviral therapy (ART) or antiretroviral prophylaxis to ...
Khine Wut Yee Kyaw, Aye Aye Mon, Khaing Hnin Phyo, Nang Thu Thu Kyaw, Ajay M. V. Kumar, Than Than Lwin, Zaw Zaw Aung, Thet Ko Aung, Myo Minn Oo, Thurain Htun, Sai Soe Thu Ya, Srinath Satyanarayana, Htun Nyunt Oo   +12 more
doaj   +1 more source