Results 101 to 110 of about 12,522,600 (400)

Single cell RNA sequencing reveals distinct clusters of Irf8-expressing pulmonary conventional dendritic cells

open access: yesFrontiers in Immunology, 2023
A single population of interferon-regulatory factor 8 (Irf8)-dependent conventional dendritic cell (cDC type1) is considered to be responsible for both immunogenic and tolerogenic responses depending on the surrounding cytokine milieu. Here, we challenge
Adan Chari Jirmo   +19 more
doaj   +1 more source

Drug-Induced Interstitial Lung Disease: A Systematic Review

open access: yesJournal of Clinical Medicine, 2018
Background: Drug-induced interstitial lung disease (DIILD) occurs as a result of numerous agents, but the risk often only becomes apparent after the marketing authorisation of such agents.
S. Skeoch   +14 more
semanticscholar   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Long-term morbidity from severe pneumonia in early childhood in The Gambia, West Africa: a follow-up study [PDF]

open access: yes, 2009
OBJECTIVE: To assess long-term outcomes in severe early childhood pneumonia in The Gambia. DESIGN: Observational cohort study of children hospitalised with severe pneumonia between 1992 and 1 04 compared to age, sex, and neigh bourhood-marched controls ...
Adegbola, RA   +6 more
core  

Successful Pregnancy in a Patient With Advanced Cystic Fibrosis Lung Disease and Burkholderia cenocepacia Colonization

open access: yesAnnals of Internal Medicine: Clinical Cases
Cystic fibrosis (CF) affects multiple aspects of health, including reproduction and fertility. This report details a case of a 38-year-old woman with several complications from her CF, including advanced CF lung disease, pancreatic exocrine insufficiency,
Isabelle Ciaverelli   +3 more
doaj   +1 more source

Cystic Fibrosis Lung Disease: An Overview

open access: yesRespiratory care, 2019
Although better insights into the natural course of cystic fibrosis (CF) have led to treatment approaches that have improved pulmonary health and increased the life expectancy of individuals with this disorder, lung disease remains the main cause of ...
N. Turcios
semanticscholar   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

Lung disease in the tropics [PDF]

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 1991
"Lung Immunology in the Tropics, Alimuddin Zumla and D. Geraint James Granulomatous Lung Diseases in the Tropics, Om P. Sharma and Gurdip S. Flora Pulmonary Complications of Malaria, Pradeep Bambery, Surinder K. Jindal, and Upjeet Kaur Melioidosis, Sumalee Kiatboonsri Pulmonary Complications of Brucellosis, A. R. Lulu and G. F.
openaire   +4 more sources

Comparison of the triglyceride lipase of liver, adipose tissue, and postheparin plasma

open access: yesJournal of Lipid Research, 1972
Heparin-released triglyceride lipase from three sources, adipose tissue, liver, and postheparin plasma, was compared. Heparin-released triglyceride lipase from liver differed in several major respects from that in adipose tissue.
John C. LaRosa   +3 more
doaj   +1 more source

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