Results 121 to 130 of about 1,504,438 (318)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Ventilator Settings and Outcome of Respiratory Failure in Chronic Interstitial Lung Disease

, 2007
Evans R. Fernández Pérez, Murat Yılmaz, Hussam Jenad, Craig Daniels, Jay H. Ryu, Rolf D. Hubmayr, Ognjen Gajic   +6 more
openalex   +2 more sources

Diffuse Lung Disease and Neurofibromatosis-1—Recurrent Association, Uncertain Relationship [PDF]

, 2012
Timothy J. Nokes, Ahmed Awab
openalex   +1 more source

Common mechanisms in chronic obstructive pulmonary disease and lung cancer

, 2021
HuiYang Zhou
openalex   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Critical evaluation of the Global DOTS Expansion Plan

Bulletin of the World Health Organization, 2007
The development of the DOTS Expansion Plan has been a milestone in tuberculosis (TB) control at the global and national levels. Key challenges that remain are overcoming the weakness of a strategy built on case management, sustaining commitment ...
Donald A Enarson, Nils E Billo
doaj  

Analysis of spermidine’s effect on coronary heart disease risk using bidirectional Mendelian randomization and LC-MS/MS

Hereditas
Background This study examines the causal relationship between spermidine levels and coronary artery disease (CHD) risk using a bidirectional Mendelian Randomization (MR) approach.
Tianyi Wang, Li Lin, Yaodong Ding, Yang Zhang, Zehao Zhao, Ruixiang Feng, Yingxuan Bai, Zhennan Li, Yuncong Shi, Na Li, Yong Zeng   +10 more
doaj   +1 more source

A RARE CASE OF MIXED NONTUBERCULOID MYCOBACTERIUM LUNG DISEASE DUE TO MYCOBACTERIUM AVIUM INTRACELLULARE AND MYCOBACTERIUM KANSASII [PDF]

, 2023
DANIEL A ACOSTA, CYNTHIA ESPINOSA, L.I. Mendez Morente, ADOLFO ALVAREZ, Nicholas Camps, JASON KOVACEVIC   +5 more
openalex   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Telerehabilitation program maintains functional capacity in patients with chronic lung disease during a period of social isolation owing to covid-19 (Preprint)

, 2022
Aline Paula Miozzo, Natiele Camponogara Righi, Maria Luiza Yumi Shizukuishi, Hérica Ferreira Marques, Juliessa Florian, Scheila da Costa Machado, Jociane Schardong, Rodrigo Della Méa Plentz   +7 more
openalex   +1 more source