Results 191 to 200 of about 1,504,438 (318)

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Interstitial lung disease in systemic sclerosis-a retrospective cross-sectional study in Taiwan. [PDF]

Clin Rheumatol
Liu CW, Chang YA, Yu CL, Tsai HC, Chen WS, Ho IC, Sun YS, Liao HT, Tsai CY.   +8 more
europepmc   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source

Lycopene Inhibits Smoke-Induced Chronic Obstructive Pulmonary Disease and Lung Carcinogenesis by Modulating Reverse Cholesterol Transport in Ferrets

, 2019
Jelena Mustra Rakic, Chun Liu, Sudipta Veeramachaneni, Dayong Wu, Ligi Paul, C.-Y. Oliver Chen, Lynne M. Ausman, Xiangdong Wang   +7 more
openalex   +2 more sources

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

Pulmonary lymphangitic carcinomatosis mimicking interstitial lung disease. [PDF]

Respir Med Case Rep
Galbreath IM, Patel HB, Singh R, Zhang C.   +3 more
europepmc   +1 more source

Diagnostic and prognostic implications of family history of fibrotic interstitial lung diseases

Shull, Jessica Germaine, Duminy-Luppi, Diego, Alcaide Aldeano, Alex, Planas Cerezales, Lurdes, Bermudo, Guadalupe, Vicens-Zygmunt, Vanesa, Luburich Hernaiz, Patricio, Del Río Carrero, Belén, Llatjós, Roger, Pijuan, Lara, Escobar Campuzano, Ignacio, Rivas Doyague, Francisco, Montes Worboys, Ana, Gutiérrez Rodríguez, Yasmina, Rodríguez-Plaza, David, Padró i Miquel, Ariadna, Esteve García, Anna, Fernández-Varas, Beatriz, Flores, Carlos, Fuentes Prado, Mireya, Dorca i Sargatal, Jordi, Santos Pérez, Salud, Perona, Rosario, Günther, Andreas, Molina-Molina, María   +24 more
openalex   +1 more source

SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas, Pablo Iruzubieta, Alberto Damborenea, Laura Pérez‐Fernández, Inmaculada Azorín, Juan Carlos Jiménez García, Ana Töpf, Pilar Martí, Lorena Fores‐Toribio, María Manterola, Rosana Blanco‐Mañez, Oihane Pikatza‐Menoio, Sonia Alonso‐Martín, Volker Straub, Aitziber L. Cortajarena, Adolfo López de Munain, David De Sancho, Lorea Blázquez, Juan J. Vilchez   +18 more
wiley   +1 more source

Does echinococcosis in a tanner represent a neglected occupational lung disease? [PDF]

Lung India
Siozos P, Mitsos S, Raptakis T, Karakatsani A.   +3 more
europepmc   +1 more source