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Cytokine release syndrome (CRS) is a severe and life‐threatening toxicity typically reported in chimeric antigen receptor T cell therapy and is rarely reported in immune checkpoint inhibitor (ICI) therapy.
Toshiharu Tsutsui+5 more
doaj +1 more source
Eosinophil and T Cell Markers Predict Functional Decline in COPD Patients [PDF]
BACKGROUND. The major marker utilized to monitor COPD patients is forced expiratory volume in one second (FEV1). However, asingle measurement of FEV1 cannot reliably predict subsequent decline.
A Papi+43 more
core +4 more sources
Background: In collaboration with the national AIDS program, early infant diagnosis (EID) is implemented by Integrated HIV Care (IHC) program through its anti-retroviral therapy (ART) centers across 10 cities in five states and regions of Myanmar.
Soe Thiha+8 more
doaj +1 more source
An amendment to this paper has been published and can be accessed via the original article.
John A. Marwick+4 more
doaj +1 more source
Quantitative CT analysis in patients with pulmonary emphysema: is lung function influenced by concomitant unspecific pulmonary fibrosis? [PDF]
Purpose: Quantitative analysis of CT scans has proven to be a reproducible technique, which might help to understand the pathophysiology of chronic obstructive pulmonary disease (COPD) and combined pulmonary fibrosis and emphysema.
Doellinger, Felix+5 more
core +1 more source
Autoinflammatory disease in the lung [PDF]
SummaryAscertaining the dominant cell type driving an immunological disease is essential to understanding the causal pathology and, therefore, selecting or developing an effective treatment. Classifying immunological diseases in this way has led to successful treatment regimens for many monogenic diseases; however, when the dominant cell type is ...
Scambler, T+4 more
openaire +3 more sources
Factors associated with long turnaround time for early infant diagnosis of HIV in Myanmar
Background: A previous review of early infant diagnosis (EID) using polymerase chain reaction technology (PCR) under integrated HIV care (IHC) program in Myanmar revealed a low uptake of timely (within 6 to 8 weeks of babies’ age) EID and a long ...
Soe Thiha+8 more
doaj +1 more source
Comorbidities in interstitial lung diseases
Fibrosing lung disorders include a large number of diseases with diverse behaviour. Patients can die because of the progression of their illness, remain stable or even improve after appropriate treatment has been instituted.
George A. Margaritopoulos+2 more
doaj +1 more source
Extensive scars develop in deep wounds as opposed to superficial wounds but it is unclear why. Here, the authors use live imaging of physiologic wounds and scars formed ex vivo to show that fascia fibroblasts upregulate N-cadherin allowing coordinated ...
Dongsheng Jiang+18 more
doaj +1 more source
Background Mitochondrial damage and dysfunction have been reported in airway and quadriceps muscle cells of patients with chronic obstructive pulmonary disease (COPD).
Gulam Haji+9 more
doaj +1 more source