Results 61 to 70 of about 12,522,600 (400)

Autoinflammatory disease in the lung [PDF]

Immunology, 2018
SummaryAscertaining the dominant cell type driving an immunological disease is essential to understanding the causal pathology and, therefore, selecting or developing an effective treatment. Classifying immunological diseases in this way has led to successful treatment regimens for many monogenic diseases; however, when the dominant cell type is ...
Scambler, T, Holbrook, J, Savic, S, McDermott, MF, Peckham, D   +4 more
openaire   +3 more sources

Early infant diagnosis of HIV in Myanmar: call for innovative interventions to improve uptake and reduce turnaround time

Global Health Action, 2017
Background: In collaboration with the national AIDS program, early infant diagnosis (EID) is implemented by Integrated HIV Care (IHC) program through its anti-retroviral therapy (ART) centers across 10 cities in five states and regions of Myanmar.
Soe Thiha, Hemant Deepak Shewade, Sairu Philip, Thet Ko Aung, Nang Thu Thu Kyaw, Myo Minn Oo, Khine Wut Yee Kyaw, May Wint War, Htun Nyunt Oo   +8 more
doaj   +1 more source

Cytokine release syndrome complicated with severe rashes induced by nivolumab plus ipilimumab therapy in a patient with non‐small cell lung cancer: A case report

Thoracic Cancer, 2023
Cytokine release syndrome (CRS) is a severe and life‐threatening toxicity typically reported in chimeric antigen receptor T cell therapy and is rarely reported in immune checkpoint inhibitor (ICI) therapy.
Toshiharu Tsutsui, Koki Hata, Makoto Kawaguchi, Hiroaki Kobayashi, Yumiko Kakizaki, Yoshihiro Miyashita   +5 more
doaj   +1 more source

Identification of an apoC-II variant (apoC-IIBethesda) in a kindred with apoC-II deficiency and type I hyperlipoproteinemia.

Journal of Lipid Research, 1988
Apolipoprotein (apo) C-II deficiency is characterized by elevated plasma triglycerides, chylomicrons, and very low density lipoproteins, as well as reduced levels of low density and high density lipoproteins.
D L Sprecher, L Taam, R E Gregg, S S Fojo, D M Wilson, M L Kashyap, H B Brewer, Jr   +6 more
doaj   +1 more source

Pulmonary hypertension in chronic lung disease and hypoxia

European Respiratory Journal, 2019
Pulmonary hypertension (PH) frequently complicates the course of patients with various forms of chronic lung disease (CLD). CLD-associated PH (CLD-PH) is invariably associated with reduced functional ability, impaired quality of life, greater oxygen ...
S. Nathan, J. Barberà, S. Gaine, S. Harari, F. Martinez, H. Olschewski, K. Olsson, A. Peacock, J. Pepke-Zaba, S. Provencher, N. Weissmann, W. Seeger   +11 more
semanticscholar   +1 more source

Guanylyl cyclase activation reverses resistive breathing–induced lung injury and inflammation [PDF]

, 2015
Inspiratory resistive breathing (RB), encountered in obstructive lung diseases, induces lung injury. The soluble guanylyl cyclase (sGC)/cyclic guanosine monophosphate (cGMP) pathway is down-regulated in chronic and acute animal models of RB, such as ...
Brouckaert, Peter, Dettoraki, Maria, Giannis, Athanassios, Glynos, Constantinos, Karavana, Vassiliki, Kotsikoris, Vasilis, Loverdos, Konstantinos, Magkou, Christina, Papapetropoulos, Andreas, Pavlidou, Athanasia, Perlikos, Fotis, Theocharis, Stamatios E, Topouzis, Stavros, Toumpanakis, Dimitris, Vassilakopoulos, Theodoros, Zhou, Zongmin   +15 more
core   +2 more sources

Injury triggers fascia fibroblast collective cell migration to drive scar formation through N-cadherin

Nature Communications, 2020
Extensive scars develop in deep wounds as opposed to superficial wounds but it is unclear why. Here, the authors use live imaging of physiologic wounds and scars formed ex vivo to show that fascia fibroblasts upregulate N-cadherin allowing coordinated ...
Dongsheng Jiang, Simon Christ, Donovan Correa-Gallegos, Pushkar Ramesh, Shruthi Kalgudde Gopal, Juliane Wannemacher, Christoph H. Mayr, Valerio Lupperger, Qing Yu, Haifeng Ye, Martin Mück-Häusl, Vijayanand Rajendran, Li Wan, Juan Liu, Ursula Mirastschijski, Thomas Volz, Carsten Marr, Herbert B. Schiller, Yuval Rinkevich   +18 more
doaj   +1 more source

Lung volumes identify an at-risk group in persons with prolonged secondhand tobacco smoke exposure but without overt airflow obstruction. [PDF]

, 2018
IntroductionExposure to secondhand smoke (SHS) is associated with occult obstructive lung disease as evident by abnormal airflow indices representing small airway disease despite having preserved spirometry (normal forced expiratory volume in 1 s-to ...
Arjomandi, Mehrdad, Blanc, Paul D, Bos, Bruce, Elicker, Brett, Geerts, Jeroen, Gold, Warren M, Keene, Jason, Stiner, Rachel K, van Koeverden, Ian, Zeng, Siyang   +9 more
core   +2 more sources

Apolipoprotein B synthesized by Hep G2 cells undergoes fatty acid acylation.

Journal of Lipid Research, 1988
Apolipoprotein B is the principal protein associated with cholesterol transport in the blood and has been proposed to play a central role in human atherogenesis.
J M Hoeg, M S Meng, R Ronan, S J Demosky, Jr, T Fairwell, H B Brewer, Jr   +5 more
doaj   +1 more source

Determination of The Relationship Between Severity of Obstructive Sleep Apnea And Chronic Obstructive Pulmonary Disease [PDF]

Journal of Cardio-Thoracic Medicine, 2017
Introduction: Chronic obstructive pulmonary disease (COPD) patients are at increased risk of sleep-disorders. The concomitant occurrence of COPD and obstructive sleep apnea hypopnea syndrome (OSAHS) is named overlap syndrome. This study aimed to evaluate
Vahid Dehestani, Fariba Rezaeetalab, Mahnaz Amini, Davood Attaran, Leila Ghofraniha, Mohammadreza kasraei   +5 more
doaj   +1 more source