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ERS statement on standardisation of cardiopulmonary exercise testing in chronic lung diseases [PDF]
The objective of this document was to standardise published cardiopulmonary exercise testing (CPET) protocols for improved interpretation in clinical settings and multicentre research projects.
Aguilaniu+88 more
core +4 more sources
Lung Cancer and Interstitial Lung Diseases. [PDF]
Lung cancer continues to be one of the leading causes of cancer-related death worldwide. There is evidence of a complex interplay between lung cancer and interstitial lung disease (ILD), affecting disease progression, management strategies, and patient outcomes. Both conditions develop as the result of common risk factors such as smoking, environmental
Drakopanagiotakis F+6 more
europepmc +3 more sources
Calprotectin in Lung Diseases [PDF]
Calprotectin (CLP) is a heterodimer formed by two S-100 calcium-binding cytosolic proteins, S100A8 and S100A9. It is a multifunctional protein expressed mainly by neutrophils and released extracellularly by activated or damaged cells mediating a broad range of physiological and pathological responses.
Ourania S. Kotsiou+3 more
openaire +4 more sources
A roadmap to pulmonary delivery strategies for the treatment of infectious lung diseases
Pulmonary drug delivery is a highly attractive topic for the treatment of infectious lung diseases. Drug delivery via the pulmonary route offers unique advantages of no first-pass effect and high bioavailability, which provides an important means to ...
Siqin He+5 more
semanticscholar +1 more source
IL-17 Cytokines and Chronic Lung Diseases
IL-17 cytokines are expressed by numerous cells (e.g., gamma delta (γδ) T, innate lymphoid (ILC), Th17, epithelial cells). They contribute to the elimination of bacteria through the induction of cytokines and chemokines which mediate the recruitment of ...
F. Ritzmann+4 more
semanticscholar +1 more source
Background Idiopathic pulmonary fibrosis (IPF) and chronic hypersensitivity pneumonitis share commonalities in pathogenesis shifting haemostasis balance towards the procoagulant and antifibrinolytic activity.
Małgorzata Sobiecka+10 more
doaj +1 more source
Fibrinolytic Therapy in Purulent Pericarditis
Purulent pericarditis (PP) is rare disease, and if left untreated, it is associated with very high mortality, nearly 100%. A considerable clinical problem due to PP is a very high probability of developing constrictive pericarditis (CP).
Małgorzata Dybowska+4 more
doaj +1 more source
Multifaceted Roles of Ferroptosis in Lung Diseases
Ferroptosis is a distinct type of programmed cell death (PCD) that depends on iron and is characterized by the accumulation of intracellular iron, exhaustion of glutathione, deactivation of glutathione peroxidase, and promotion of lipid peroxidation ...
Yi Li, Ying Yang, Yongfeng Yang
semanticscholar +1 more source
The Role of Macrophages in the Development of Acute and Chronic Inflammatory Lung Diseases
Macrophages play an important role in the innate and adaptive immune responses of organ systems, including the lungs, to particles and pathogens. Cumulative results show that macrophages contribute to the development and progression of acute or chronic ...
Jae-Won Lee+7 more
semanticscholar +1 more source