Results 81 to 90 of about 637,902 (343)

Disintegration of the KITENIN/ErbB4 Functional Complex by the Flavonoid Hispidulin Suppresses Colorectal Cancer Progression

Advanced Therapeutics, EarlyView.
Hispidulin disrupts the KITENIN/ErbB4 oncogenic complex and inhibits KITENIN‐mediated AP‐1 activity, cell invasion, and aerobic glycolysis. It also suppresses the production of cancer‐associated metabolites and downregulates transcriptional regulators downstream of the KITENIN complex.
Mücahit Varlı, Songjin Oh, Eunae Kim, Barış Gökalsın, Nüzhet Cenk Sesal, Kyung Keun Kim, Man Jeong Paik, Hangun Kim   +7 more
wiley   +1 more source

Immune responses to airborne fungi and non-invasive airway diseases. [PDF]

, 2014
Inhalation of fungal particles is a ubiquitous way of exposure to microorganisms during human life; however, this exposure may promote or exacerbate respiratory diseases only in particular exposure conditions and human genetic background.
Niculita-Hirzel, Hélène, Roger, Thierry, Vacher, Gaëlle   +2 more
core   +1 more source

Hydrophobin‐Coated Echogenic Microbubbles for Molecular Targeting of Tumor Cells

Advanced Science, EarlyView.
Echogenic microbubbles based on hydrophobin and corresponding fusion protein (HFBI‐domZ) are developed as contrast agents for cancer diagnostics. Hydrophobin provides high stabilization of encapsulated perfluoro‐n‐butane, and fusion proteins allow further versatile functionalization with antibodies. In‐vitro experiments indicate that these microbubbles
Hedar H. Al‐Terke, Grégory Beaune, Muhammad Junaid, Jani Seitsonen, Arja Paananen, Pierangelo Metrangolo, Jaakko V. I. Timonen, Jussi Joensuu, Robin H. A. Ras   +8 more
wiley   +1 more source

Microarray detection of human parainfluenzavirus 4 infection associated with respiratory failure in an immunocompetent adult. [PDF]

, 2006
A pan-viral DNA microarray, the Virochip (University of California, San Francisco), was used to detect human parainfluenzavirus 4 (HPIV-4) infection in an immunocompetent adult presenting with a life-threatening acute respiratory illness.
Blackburn, Brian G, Chiu, Charles Y, DeRisi, Joseph L, Eckburg, Paul B, Fischer, Kael, Ganem, Don, Koshy, Anita, Merker, Jason D, Patterson, Bruce K, Rouskin, Silvi, Schnurr, David, Tompkins, Lucy S, Urisman, Anatoly, Yagi, Shigeo   +13 more
core  

Induction of diverse secondary metabolites in Aspergillus fumigatus by microbial co-culture [PDF]

, 2013
Peer reviewedPublisher ...
Abraham, Ando, Boot, Burgess, Cueto, Cui, Cui, Cámara, Fayos, Frey-Klett, Frisvad, Gibson, Gros, Hong, Jones, Kobayashi, Kronvall, Mansson, Nonaka, Nozawa, Oh, Oh, Okoro, Park, Pettit, Pettit, Rateb, Sanchez, Santhanam, Schroeckh, Seya, Shirling, Sonnenbichler, Wang, Watts, Xiang-qian, Yamazaki, Zhang, Zuck   +38 more
core   +1 more source

Tailoring a Functional Synthetic Microbial Community Alleviates Fusobacterium nucleatum‐infected Colorectal Cancer via Ecological Control

Advanced Science, EarlyView.
The bottom‐up strategy based on multiomics data is used for the SynCom design, and it successfully inhibited F. nucleatum growth and achieved stable colonization in vivo. In addition, it promoted tryptophan metabolism and secondary bile acid conversion, reduced lipid accumulation, relieved microbiome disorder, decreased inflammatory reaction, and ...
Zhongkun Zhou, Mengyue Yang, Hong Fang, Baizhuo Zhang, Yunhao Ma, Yongyuan Li, Yingjie Liu, Zeying Cheng, Yuanchun Zhao, Zhenzhen Si, Hongmei Zhu, Peng Chen   +11 more
wiley   +1 more source

Necessary and Sufficient Role for T Helper Cells To Prevent Fungal Dissemination in Allergic Lung Disease [PDF]

Infection and Immunity, 2011
ABSTRACTMucosal immune responses to fungal infection range from T helper type 2 (Th2) cell-directed allergic inflammation to Th1-predominant neutrophilic inflammation, but the mechanisms directing these divergent mucosal immune outcomes and the role of T cells in host defense against mucosal fungal infections are not known.
Morgan Knight, Luz Roberts, Shuhua Han, George L. Delclos, Farrah Kheradmand, David B. Corry, Paul Porter, Anna Fields, Yuping Qian   +8 more
openaire   +3 more sources

Burden of fungal infections in Iran

Journal of Infection in Developing Countries, 2018
Introduction: The number of fungal infections occurring each year in Iran is not known. As the burden of fungal disease is a measure used to assess and compare the relative impact of different type of fungal diseases on populations, we have estimated ...
Mohammad T Hedayati, Mojtaba Taghizadeh Armaki, Jamshid Yazdani Charati, Newsha Hedayati, Seyedmojtaba Seyedmousavi, David W Denning   +5 more
doaj   +1 more source

Transcriptome profiling of lung immune responses potentially related to acute respiratory distress syndrome in forest musk deer

BMC Genomics, 2022
Background Forest musk deer is an endangered species globally. The death of captive forest musk deer can be caused by certain respiratory system diseases.
Jie Tang, Lijuan Suo, Feiran Li, Kun Bian, Chao Yang, Yan Wang   +5 more
doaj   +1 more source

Chemical markers for the characterization of bioaerosol [PDF]

, 2017
Bioaerosol is commonly defined as aerosolized particles, with a biological origin, spread into the air by a variety of abiotic and biotic mechanisms. The size of bioaerosol can range from several nanometers to a few hundred micrometres in aerodynamic ...
Buiarelli, Francesca, Carmela, Riccardi, Donatella, Pomata, Patrizia Di, Filippo   +3 more
core   +1 more source