Results 201 to 210 of about 142,658 (312)

Overcoming intranasal delivery barriers with ultrastable polyzwitterionic siRNA nanocages for enhanced glioblastoma therapy

BMEMat, EarlyView.
A ROS‐responsive, zwitterionic nanocage enables stable, intranasal siRNA delivery to glioblastoma, promoting deep tumor penetration via non‐degradative pathways and trigeminal nerve transport. This platform achieves durable gene silencing and tumor suppression, offering a non‐invasive, storage‐stable strategy for treating glioma and other neurological ...
Jingwen Xie, Jingxing Si, Xiaobei Deng, Jing Tan, Ruijie Zhu, Jizhou Qi, Gaoxia Ma, Bin Wang, Yi Wang, Yunzhou Guo, Yuping Chen, Shiqun Shao, Youqing Shen   +12 more
wiley   +1 more source

BAL lymphocytosis as a predictive marker for drug response and long-term outcome in fibrotic ILD: systematic review. [PDF]

BMJ Open Respir Res
Suter P, Buechi AE, Roa-Diaz ZM, Funke-Chambour M.   +3 more
europepmc   +1 more source

Real time in vivo efficacy monitoring of desialylation and perforation enhanced immunotherapy of cancer

BMEMat, EarlyView.
A multifunctional nanomedicine is designed to engineer NK cells for enhanced cancer immunotherapy through perforation and desialylation, enabling real‐time monitoring of ATP and GrB levels for precise efficacy assessment. Abstract Efficient enhanced NK cell therapy is of critical importance in the immune treatment of cancer.
Yuanjiao Yang, Yuru Wang, Xuemei Li, Chaoyi Yang, Yuhui Yang, Yanyun Fang, Lin Ding, Yunlong Chen, Huangxian Ju   +8 more
wiley   +1 more source

Acute respiratory failure as a rare presentation of non-fibrotic hypersensitivity pneumonitis: Case series. [PDF]

Medicine (Baltimore)
Lewandowska KB, Opoka L, Bartoszuk I, Jędrych ME, Radwan-Rohrenschef P, Deutsch K, Roży A, Jakubowska L, Tomkowski WZ, Sobiecka M, Szturmowicz M.   +10 more
europepmc   +1 more source

Beyond wound sealing: A dual‐functional adhesive nanofiber membrane promoting coagulation and osteogenesis in extraction sites

BMEMat, EarlyView.
Inspired by the suction mechanics of octopus suckers, a dual‐layer nanofiber membrane integrates antibacterial protection, strong wet adhesion, and osteogenic support, offering a bioinspired strategy for effective hemostasis and alveolar bone preservation.
Huijing Ma, Liheng Gao, Hao Liang, Wentao Jiang, Junyi Wang, Jiajia Wang, Shuhan Duan, Lingxi Meng, Adilijiang Yimiti, Wenjie Zhang   +9 more
wiley   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

Interstitial Lung Disease in Rheumatoid Arthritis: Incidence and Outcomes in Western Australia. [PDF]

Int J Rheum Dis
Prasanna H, Inderjeeth C, Preen DB, Nossent J.   +3 more
europepmc   +1 more source

The ageing holobiont: crosstalk between telomere dynamics, oxidative stress and the gut microbiome

Biological Reviews, EarlyView.
ABSTRACT The gut tissue is at the frontline of early onset of ageing. It exhibits high cell turnover rates and rapid telomere shortening, which can have systemic effects on the developing or senescing organism. We conducted a literature review of studies on the crosstalk between telomere length dynamics, telomerase activity, oxidative stress, and gut ...
Michael L. Pepke, Søren B. Hansen, Morten T. Limborg   +2 more
wiley   +1 more source

A Successful Monitoring of a Pregnant Woman Suffering from Mixed Connective Tissue Disease-Associated Interstitial Lung Disease: A Case Report. [PDF]

Int J Womens Health
Cui X, Zhou W, Sun Y, Duan Y, Sun H.
europepmc   +1 more source

Latin American expert opinion paper on the diagnosis and treatment of pulmonary hypertension associated with interstitial lung disease. [PDF]

Front Med (Lausanne)
Lescano A, Pulido Zamudio T, Conde Camacho R, Caro FM, Espitia Hernández G, Fernandes CJCDS, García Cuéllar JA, Zagolín Blancaire M, Zayas Hernández N, Tobón M.   +9 more
europepmc   +1 more source