Results 311 to 320 of about 674,704 (375)

Mechanistic Physiologically Based Pharmacokinetic Modeling of Dry Powder and Nebulized Formulations of Orally Inhaled TMEM16A Potentiator GDC‐6988

open access: yesCPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT The orally inhaled route of administration for respiratory indications can maximize drug exposure to the site of action (lung) to increase efficacy while minimizing systemic exposure to achieve an improved safety profile. However, due to the difficulty of taking samples from different regions of the human lung, often only systemic ...
Rui Zhu   +12 more
wiley   +1 more source

Serum C-C motif chemokine ligand 17 as a predictive biomarker for the progression of non-idiopathic pulmonary fibrosis interstitial lung disease. [PDF]

open access: yesRespir Res
Enomoto T   +35 more
europepmc   +1 more source

Malignancies and immunoglobulin G4‐related disease

open access: yesRheumatology &Autoimmunity, EarlyView.
Immunoglobulin G4‐related disease (IgG4‐RD) is associated with increased cancer risk. Malignancies affect both IgG4‐RD involved organs, such as the lung, pancreas, bile duct, and prostate, and noninvolved organs, such as the gastrointestinal duct. B‐cell neoplasms constitute a proportion of the malignancies linked to this disease.
Jingna Li, Wen Zhang
wiley   +1 more source

Nitrofurantoin-Induced Pulmonary Toxicity: Mechanisms, Diagnosis, and Management. [PDF]

open access: yesToxics
Kaye AD   +7 more
europepmc   +1 more source

Artificial intelligence in rheumatoid arthritis

open access: yesRheumatology &Autoimmunity, EarlyView.
Advancements in artificial intelligence (AI) over the past 5 years have brought significant progress to the medical field, including rheumatoid arthritis (RA). AI integrates multimodal data, including clinical, imaging, omics, and longitudinal information, to enhance RA diagnosis and treatment.
Yiduo Sun, Jin Lin, Weiqian Chen
wiley   +1 more source

Lung ultrasonography as a tool to detect interstitial lung disease in rheumatoid arthritis: A meta‐analysis of diagnostic test accuracy studies

open access: yesRheumatology &Autoimmunity, EarlyView.
A systematic review and meta‐analysis were conducted to evaluate the diagnostic accuracy of lung ultrasonography (LUS) to high‐resolution computed tomography (HRCT) in detecting rheumatoid arthritis (RA)‐interstitial lung disease (ILD). Nine studies with a total of 845 participants were included.
Rudy Hidayat   +3 more
wiley   +1 more source

Predictors of systemic sclerosis patients with interstitial lung disease progression: A retrospective study

open access: yesRheumatology &Autoimmunity, EarlyView.
The final systemic sclerosis patients with interstitial lung disease (SSc‐ILD) progression prediction model was composed of 6 significant risk factors: male, type 2 diabetes mellitus, pericardial effusion, anti‐Ro52, hypoproteinemia, and elevated C‐reactive protein. Our model demonstrated excellent prognostic utility.
Xi Cao   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy