Results 51 to 60 of about 209,213 (308)

Assessment of pulmonary edema: principles and practice [PDF]

, 2018
Pulmonary edema increasingly is recognized as a perioperative complication affecting outcome. Several risk factors have been identified, including those of cardiogenic origin, such as heart failure or excessive fluid administration, and those related to ...
Assaad, Sherif, Friedman, Malcolm B., Kratzert, Wolf B., Perrino, Albert, Shelley, Benjamin   +4 more
core   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Small airway dysfunction in pneumoconiosis: a cross-sectional study

BMC Pulmonary Medicine, 2022
Background Although several histological studies have documented airway inflammation and remodelling in the small airways of dust-exposed workers, little is known regarding the prevalence and risk factors of small airway dysfunction (SAD) in ...
Yali Fan, Ruimin Ma, Xuqin Du, Dandan Chai, Shuangli Yang, Qiao Ye   +5 more
doaj   +1 more source

Is the internet a sufficient source of information on sarcoidosis?

Frontiers in Medicine, 2023
IntroductionMany patients use the internet as a source of health information. Sarcoidosis is a complex disease, and internet resources have not yet been analyzed for reliability and content on sarcoidosis.AimsOur study aimed to investigate the content ...
Katharina Buschulte, Philipp Höger, Claudia Ganter, Marlies Wijsenbeek, Nicolas Kahn, Katharina Kriegsmann, Finn M. Wilkens, Jolene H. Fisher, Christopher J. Ryerson, Felix J. F. Herth, Michael Kreuter, Michael Kreuter   +11 more
doaj   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Decreased serpin C1 in extracellular vesicles predicts response to methotrexate treatment in patients with pulmonary sarcoidosis

Respiratory Research
Background Sarcoidosis is a systemic granulomatous disease of unknown etiology primarily affecting the lungs. Treatment is needed when disease symptoms worsen and organ function deteriorates.
Raisa Kraaijvanger, Montse Janssen Bonás, Jan C. Grutters, Ioanna Paspali, Marcel Veltkamp, Dominique P. V. de Kleijn, Coline H. M. van Moorsel   +6 more
doaj   +1 more source

Activation of Downstream mTORC1 Target Ribosomal Protein S6 Kinase (S6K) Can Be Found in a Subgroup of Dutch Patients with Granulomatous Pulmonary Disease

Cells, 2021
Mechanistic target of rapamycin complex 1 (mTORC1) has been linked to different diseases. The mTORC1 signaling pathway is suggested to play a role in the granuloma formation of sarcoidosis.
Raisa Kraaijvanger, Kees Seldenrijk, Els Beijer, Jan Damen, Jayne Louise Wilson, Thomas Weichhart, Jan C. Grutters, Marcel Veltkamp   +7 more
doaj   +1 more source

A common microbial signature is present in the lower airways of interstitial lung diseases including sarcoidosis [PDF]

, 2018
Background: The etiology of pulmonary sarcoidosis is not well established. Although the mechanism triggering pulmonary sarcoidosis remains to be established, inflammatory reactions seem to play an important role in this process.
Bocchino, Marialuisa, Casaburi, Giorgio, D'Argenio, Valeria, MOCCIA, LIVIO GIOACCHINO, Postiglione, Irene, Precone, Vincenza, Sanduzzi, Alessandro   +6 more
core  

Guanylyl cyclase activation reverses resistive breathing–induced lung injury and inflammation [PDF]

, 2015
Inspiratory resistive breathing (RB), encountered in obstructive lung diseases, induces lung injury. The soluble guanylyl cyclase (sGC)/cyclic guanosine monophosphate (cGMP) pathway is down-regulated in chronic and acute animal models of RB, such as ...
Brouckaert, Peter, Dettoraki, Maria, Giannis, Athanassios, Glynos, Constantinos, Karavana, Vassiliki, Kotsikoris, Vasilis, Loverdos, Konstantinos, Magkou, Christina, Papapetropoulos, Andreas, Pavlidou, Athanasia, Perlikos, Fotis, Theocharis, Stamatios E, Topouzis, Stavros, Toumpanakis, Dimitris, Vassilakopoulos, Theodoros, Zhou, Zongmin   +15 more
core   +2 more sources

A 73‐Year‐Old Man With Several Years of Difficulty Climbing Stairs and Frequent Tripping

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 73‐year‐old man presented with progressive weakness and atrophy predominantly affecting the distal finger flexors and quadriceps muscles. Electrophysiological studies demonstrated mixed myogenic and neurogenic features. Muscle MRI showed inflammatory changes, and muscle biopsy revealed granulomatous myositis with histologic features ...
Mehmet Can Sari, Arens Taga, Sonya Ulrike Steele, Ahmet Hoke   +3 more
wiley   +1 more source