Results 221 to 230 of about 801,766 (352)

Screening and Identification of Novel DNA Aptamer for Targeted Delivery to Injured Podocytes in Glomerular Diseases

Advanced Science, EarlyView.
This study develops RLS‐2, a high‐affinity aptamer that specifically targets injured podocytes, making it a promising candidate for targeted drug delivery. In vitro, RLS‐2 shows stability, specificity, efficient siRNA delivery via AsiCs, and uptake by podocytes.
Chao Zhou, Zhaofeng Luo, Zheng Zhang, Qing Ye, Dongjie Wang, Hanyan Meng, Jiayu Zhang, Shifan Zhu, Lidan Hu, Jianhua Mao   +9 more
wiley   +1 more source

Critical analysis of spirometry interpretation in tuberculosis-related lung function impairment: a commentary on a Chinese study. [PDF]

BMC Pulm Med
Barkous B, Boubakri S, Saad HB.
europepmc   +1 more source

Elucidating COPD pathogenesis by large-scale genetic analyses [PDF]

, 2015
Bracke, Ken, Brusselle, Guy
core   +1 more source

Enhancing Osteogenesis through Bio‐Inspired Recombinant Coral Protein Galaxin by Targeting Mitochondrial Metabolism and ATP Production

Advanced Science, EarlyView.
The study highlights the potential of recombinant galaxin (a coral protein) as a novel and effective biomaterial for bone regeneration. It binds to ATP synthase subunit β (ATP5B) in mouse pre‐osteoblasts, thereby causing increased ATP production and mitochondrial activity.
Fei Yu, Xing Zhao, Ting Jiang, Ningjuan Ouyang, Peilin Li, Wei Yang, Zhihe Zhao   +6 more
wiley   +1 more source

The Impact of Age and Disease Entity on Small Airway Dysfunction in Obstructive Airway Diseases. [PDF]

Int J Chron Obstruct Pulmon Dis
Li Y, Su KC, Hsiao YH, Chou KT, Li YJ, Jeng TH, Ko HK, Perng DW.   +7 more
europepmc   +1 more source

Chronic obstructive lung disease

Journal of Physiotherapy, 2013
openaire   +3 more sources

Histone Deacetylase 6 (HDAC6) in Ciliopathies: Emerging Insights and Therapeutic Implications

Advanced Science, EarlyView.
HDAC6 regulates primary cilia, crucial for cellular signalling and environmental responses. Dysregulation of HDAC6 contributes to ciliopathies, affecting multiple organs. This review examines HDAC6's role in ciliogenesis, its interaction with signaling molecules, and its potential as a therapeutic target.
Zhiyi Wang, Xiaofan Zhu, Zhenzhou Huang, Kaidi Ren, Jie Ran, Yang Yang   +5 more
wiley   +1 more source

Respiratory health and chronic disease risks in residents of agricultural areas in Chiang Mai, Northern Thailand. [PDF]

PLoS One
Wongta A, Pata S, Chawansuntati K, Yodkeeree S, Hongsibsong S, Khamduang W.   +5 more
europepmc   +1 more source

Icaritin Represses Autophagy to Promote Colorectal Cancer Cell Apoptosis and Sensitized Low‐Temperature Photothermal Therapy via Targeting HSP90‐TXNDC9 Interactions

Advanced Science, EarlyView.
Icaritin demonstrates broad antitumor effects by inhibiting colorectal cancer (CRC) cell proliferation, migration, invasion, and causing cell cycle arrest. It induces apoptosis by repressing autophagic flux through disrupting HSP90‐TXNDC9 interactions.
Dan He, Siliang Chen, Xiaoyun Wang, Xiang Wen, Changyang Gong, Lei Liu, Gu He   +6 more
wiley   +1 more source

Editorial: Reviews in: pulmonary medicine 2023. [PDF]

Front Med (Lausanne)
Carbone RG, Puppo F.
europepmc   +1 more source