Results 201 to 210 of about 934,333 (350)

Elastic properties of the central airways in obstructive lung diseases measured using anatomical optical coherence tomography.

American Journal of Respiratory and Critical Care Medicine, 2011
J. Williamson, R. McLaughlin, W. Noffsinger, A. James, V. Baker, A. Curatolo, J. Armstrong, A. Regli, K. Shepherd, G. Marks, D. Sampson, D. Hillman, P. Eastwood   +12 more
semanticscholar   +1 more source

Neuid: A Novel Neuron‐Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease

Advanced Science, EarlyView.
ABSTRACT The increasing evidence that non‐coding RNAs can become deregulated during pathogenesis is dramatically expanding the space for drug discovery beyond the protein‐coding genome. Long noncoding RNAs (lncRNAs) are emerging as key regulators of cellular function, yet most remain uncharacterized.
Ranjit Pradhan, Zorica Petrovic, M. Sadman Sakib, Sophie Schröder, Dennis Manfred Krüger, Tonatiuh Pena, Eren Diniz, Susanne Burkhardt, Anna‐Lena Schütz, Verena Gisa, Iga Grzadzielewska, Karl Toischer, Thor D. Stein, Jan Krzysztof Blusztajn, Ivana Delalle, Jelena Radulovic, Farahnaz Sananbenesi, Andre Fischer   +17 more
wiley   +1 more source

Sex Differences in Muscle-Respiratory Function Relationship in Lung Transplant Patients: A Longitudinal Study. [PDF]

J Cachexia Sarcopenia Muscle
Ceolin C, Alessi A, Citron A, Loy M, Papa MV, Andaloro C, Zanforlini BM, Devita M, Bertolino S, Gonnelli S, Seccia DM, Bertocco A, Rea F, Sergi G, De Rui M.   +14 more
europepmc   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Fatal <i>Pasteurella multocida</i> pneumonia and bacteremia in a patient with chronic obstructive pulmonary disease: A case report with autopsy findings. [PDF]

IDCases
Okusaki T, Nimiya M, Sumimoto N, Oue N, Awaya Y.   +4 more
europepmc   +1 more source

Metabolic reprogramming in the pathogenesis of chronic lung diseases, including BPD, COPD, and pulmonary fibrosis.

American Journal of Physiology - Lung cellular and Molecular Physiology, 2018
Haifeng Zhao, P. Dennery, H. Yao
semanticscholar   +1 more source

Halofuginone is a Molecular Glue Degrader of Integrin β4

Advanced Science, EarlyView.
Integrin β4 overexpression is linked to aggressive tumors and poor prognosis, but targeted therapies are lacking. We identified halofuginone (HF) as a molecular glue degrader that promotes integrin β4 degradation via the CRL4BWDR18 E3 ligase. HF suppresses tumor progression in vitro and in vivo, offering a new strategy for targeting oncogenic ...
Wei Gong, Di Yang, Junrui Tian, Yufei Chai, Tiantian Yu, Qingnan Wu, Yan Wang, Weimin Zhang, Qimin Zhan   +8 more
wiley   +1 more source

Excessive dynamic airway collapse: A condition behind the veil. [PDF]

World J Methodol
Paudyal V, Thapa R, Itani A, Sharma M, Rayamajhi R, Ratnani I, Surani S.   +6 more
europepmc   +1 more source

A Nanoparticle‐Integrated Complete Manufacturing Pipeline of Chemically Engineered Exosomes

Advanced Science, EarlyView.
We report a novel manufacture technology of chemically engineered exosomes. The four steps of manufacturing, i.e., biogenesis, loading, isolation, and storage, are integrated by the use of a nanoparticle. The manufacture technology incorporates three innovative components, i.e., a new nano‐bio effect, a new composite nanoparticle, and a new isolation ...
Xiaowei Wen, Zixing Xu, Zerun Hao, Yanming Chen, Kai Xie, Haofan Yin, Xueying Wang, Jie Min, Sihan Sun, Baiding Chen, Chengxiu Ling, Mingming Xu, Yizhao Chen, Gang Ruan   +13 more
wiley   +1 more source

Alterations to the Bronchial Gene-Expression Effects of Tobacco Smoking in People Living With HIV. [PDF]

J Acquir Immune Defic Syndr
Lee M, Olson A, Pickering RT, Ieong MH, Kivett D, Roche S, Xiao X, Liu G, Asundi A, Lin NH, Lenburg ME.   +10 more
europepmc   +1 more source