Results 191 to 200 of about 934,333 (350)

Association between hypertension and impaired lung function among adults: A systematic review and meta-analysis. [PDF]

PLoS One
Lekamge D, Kasturiratne A, Mridha MK, Chambers J.   +3 more
europepmc   +1 more source

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

Advanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong, Lingshuang Wang, Hui Zhang, Menghuan Li, Zhong Luo, Yan Hu, Chunyuan Cai   +6 more
wiley   +1 more source

Antimicrobial resistance genes and antibiotic use in chronic lung disease: a bronchoscopy study of the lower airways microbiome. [PDF]

BMJ Open Respir Res
Kringeland GD, Tangedal S, Julian D, Paytuví-Gallart A, Sanseverino W, Bertelsen RJ, Husebø GR, Knudsen KS, Lehmann S, Nielsen R, Eagan TML.   +10 more
europepmc   +1 more source

Fibrates Inhibit PLTP‐induced M2 Macrophage Infiltration and Increase the Sensitivity of Hepatocellular Carcinoma to ICIs

Advanced Science, EarlyView.
Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang, Yaning Li, Jianxun Cai, Lisi Luo, Pengfei Yang, Yutong Chen, Jiancong Zhou, Yan Zeng, Jiaping Yu, Weiyu Zhang, Wenzheng Pang, Yufang Li, Chunhua Wen, Jian Li, Linjuan Zeng   +14 more
wiley   +1 more source

History of Chronic Obstructive Pulmonary Disease May Contribute to Earlier Diagnosis of Lung Cancer. [PDF]

In Vivo
Marel M, Domecky P, Fernando CML, Bejckova A, Fila L, Hrnciarik M, Vencalek T, Roubec J, Duba J, Svaton M.   +9 more
europepmc   +1 more source

TRMT6‐Mediated m1A Modification of CDK9 mRNA Is a Dual‐Pronged Pathogenic Driver for HBV‐Related Hepatocellular Carcinoma

Advanced Science, EarlyView.
TRMT6‐mediated m1A modification in CDK9 mRNA enhances its mRNA stability and translation efficiency, thereby increasing the protein levels of CDK9. Upregulated CDK9 promotes the progression of HCC by elevating the levels of oncogenic factors including p‐STAT3, MCL1, and BCL‐2. On the other hand, CDK9 phosphorylates TARDBP at Ser254 to activate HBV core
Rui Zhang, Dandan Zong, Rui Liu, Yubo Wang, Qingqing Gu, Yao Yao, Wenfang Zheng, Mengmeng Yuan, Simeng Wang, Rongrong Cui, Daxu Li, Siwen Dang, Peng Hou   +12 more
wiley   +1 more source

Cross-sectional study on the relationship between sarcopenia indicators and lung function in a community-dwelling population. [PDF]

Front Nutr
Feng X, Zheng L, Niu Y, Wang K, Wang J, Qiao L, Yang S, Li H, Lu W, Li S, Xie H, Zheng Y, Zhang W, Feng Z, Chen X.   +14 more
europepmc   +1 more source

Paving the Way to Elucidate Hg's Role in Tumorigenesis

Advanced Science, EarlyView.
Tumorigenesis can result from diverse environmental carcinogens. Among them, mercury—a lifelong bioaccumulative Group 2B carcinogen—has tumorigenic potential that remains poorly understood due to confounding co‐exposures and limited organ‐specific data.
Shouying Li, Rong Zhong, Zhenyang Yu, Hualing Fu, Jin Chen, Jia Wei, Ningwei Zhao, Le Qu, Tiantian Li, Wenli Tang, Huan Zhong   +10 more
wiley   +1 more source

Impulse oscillometry and traditional pulmonary function testing: correlation, advances and clinical implications. [PDF]

BMJ Open Respir Res
Yao S, Huang L, Chen B, Ji L, Zheng J, Gao Y.   +5 more
europepmc   +1 more source

MCV/Q, Medical College of Virginia Quarterly, Vol. 15 No. 3 [PDF]

, 1979

core   +1 more source