Results 111 to 120 of about 60,558 (272)

Type‐2‐Inflammatory‐Diseases Share Comorbidities, Molecular Signatures, IL4/IL13 Genetics, and Response to IL4/IL13 Blockade

open access: yesAllergy, EarlyView.
Studies suggest that type 2 inflammatory diseases are driven by overactivation of the IL4/IL13 pathway, manifesting differently in distinct tissues. We performed quantitative analyses using several large independent datasets to explore the interrelation of type 2 inflammatory diseases based on co‐prevalence, genetic predispositions, and transcriptomic ...
Jennifer D. Hamilton   +19 more
wiley   +1 more source

Comments and illustrations of the EFSUMB guidelines. Parasitic diseases of the lungs and pleura.

open access: yesMedical Ultrasonography
Parasitic infections of the lungs and pleura are uncommon but clinically significant, affecting both endemic and non-endemic areas due to global travel and migration. While computed tomography (CT) remains the imaging modality of choice, thoracic ultrasound, particularly in peripheral and pleural lesions, offers a valuable, non-invasive complement ...
Kathleen, Möller, Christoph F, Dietrich
openaire   +2 more sources

Analysis of the human diseasome reveals phenotype modules across common, genetic, and infectious diseases [PDF]

open access: yes, 2014
Phenotypes are the observable characteristics of an organism arising from its response to the environment. Phenotypes associated with engineered and natural genetic variation are widely recorded using phenotype ontologies in model organisms, as are signs
Gkoutos, Georgios V   +2 more
core   +2 more sources

Infection control in the brain and the eye

open access: yesActa Ophthalmologica, EarlyView.
Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester   +2 more
wiley   +1 more source

Mortality in young adults following in utero and childhood exposure to arsenic in drinking water. [PDF]

open access: yes, 2012
BackgroundBeginning in 1958, the city of Antofagasta in northern Chile was exposed to high arsenic concentrations (870 µg/L) when it switched water sources. The exposure abruptly stopped in 1970 when an arsenic-removal plant commenced operations.
Ferreccio, Catterina   +5 more
core   +1 more source

Prevalence of Common Food-Borne Parasitic Diseases in Slaughtered Ruminants in West Part of Iran

open access: yesJournal of Food Quality and Hazards Control, 2017
Background: To obtain update information on the prevalence of common food-borne parasitic diseases, this study designed to determine the prevalence of hydatidosis and liver flukes (Fasciola spp.
Y. Shahbazi, A.A. Chalehchaleh
doaj  

The river blindness drug Ivermectin and related macrocyclic lactones inhibit WNT‐TCF pathway responses in human cancer

open access: yesEMBO Molecular Medicine, 2014
Constitutive activation of canonical WNT‐TCF signaling is implicated in multiple diseases, including intestine and lung cancers, but there are no WNT‐TCF antagonists in clinical use.
Alice Melotti   +5 more
doaj   +1 more source

Cholangiocarcinoma in a central bearded dragon (Pogona vitticeps): A case report

open access: yesAustralian Veterinary Journal, EarlyView.
Cholangiocarcinoma is an uncommon malignant epithelial tumour of the biliary tract in reptiles and is rarely reported in central bearded dragons (Pogona vitticeps). This case report describes a 7‐year‐old male central bearded dragon in which a nonspecific coelomic opacity was incidentally detected during a routine clinical examination.
M Mikiewicz   +2 more
wiley   +1 more source

Advancements in Inorganic Chiral Nanomaterials for Anti‐Tumor Immunotherapy

open access: yesCancer Science, EarlyView.
Schematic illustration of how inorganic chiral nanomaterials enhance immune activation to promote tumor cell elimination through targeted delivery, immunogenic cell death, and immune microenvironment modulation. ABSTRACT While the past decade has witnessed unprecedented technological advancements, cancer remains a major health threat, with conventional
Siyu Chen   +9 more
wiley   +1 more source

AI‐Assisted Fungal Detection in Dermatopathology: A Study on Accuracy, Efficiency, and Usability

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and Objectives AI‐based image analysis is increasingly applied in pathology. Excluding fungal elements in PAS‐stained skin sections is labor‐intensive and well suited for AI assistance. While fungal detection in nails has been studied, skin‐biopsy applications and real‐world benefit remain limited.
Paul Schmidle   +12 more
wiley   +1 more source

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