Results 91 to 100 of about 3,160,530 (245)
Nematode in Cockroaches: A Potential Allergen Source
Allergy, EarlyView.
Dongjun Kang +5 more
wiley +1 more source
Interleukin‐12: Central Roles in Immune Regulation and Disease Therapy
Immunology &Cell Biology, EarlyView.IL‐12 levels are tightly regulated to balance effective protective immunity against infections and cancer with the risk of excessive inflammation and autoimmune disease. Both insufficient and excessive IL‐12 activity can therefore be detrimental, highlighting the importance of precisely controlling its production and signaling. ABSTRACT Interleukin‐12 (
Anthi Psoma, Geert van den Bogaart
wiley +1 more source
, 2016 Eosinophilic lung diseases especially comprise eosinophilic pneumonia or as the more transient Loffler syndrome, which is most often due to parasitic infections. The diagnosis of eosinophilic pneumonia is based on characteristic clinical-imaging features
Vincent Cottin, Cottin, Vincent
core +1 more source
Dual Host–Pathogen Screening of the Lung During Severe Influenza Using Spatial Transcriptomics
Immunology &Cell Biology, EarlyView.We performed genome‐wide spatial transcriptomics at 10 μm resolution on the lungs of mice infected with influenza A virus. We utilised publicly available scRNAseq reference datasets to identify cell types present. We found viral transcripts across all detected cell types, suggesting localised indiscriminate infection.
Marcus Z. W. Tong +9 more
wiley +1 more source
, 2015 In the last 30 years studies have shown that the lungs have been the target of eosinophilic migration producing eosinophilic lung diseases (ELD) secondary to allergens, irritants, parasites, infections, antibodies and drugs.
Ribeiro, Jose Dirceu +1 more
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Tissue Resident Memory Cells: Friend or Foe?
Immunology, EarlyView.Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude +2 more
wiley +1 more source
Immunology, EarlyView.This systematic review establishes disease‐specific dysregulations of human innate lymphoid cells (ILCs), demonstrating that an ILC1/ILC3 imbalance compromises mucosal barriers in inflammatory bowel disease, while activated ILC2s drive allergic airway inflammation.
Luan F. Lückmann +7 more
wiley +1 more source
Saving lives and protecting people from parasitic disease [PDF]
Parasitic diseases, including malaria and neglected tropical diseases (NTDs), cause devastating illness among billions of people and economic burden around the world and in the United States, threatening local populations, businesses, travelers, and ...
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Prevalence of Common Food-Borne Parasitic Diseases in Slaughtered Ruminants in West Part of Iran
Journal of Food Quality and Hazards Control, 2017 Background: To obtain update information on the prevalence of common food-borne parasitic diseases, this study designed to determine the prevalence of hydatidosis and liver flukes (Fasciola spp.
Y. Shahbazi, A.A. Chalehchaleh
doaj
EMBO Molecular Medicine, 2014 Constitutive activation of canonical WNT‐TCF signaling is implicated in multiple diseases, including intestine and lung cancers, but there are no WNT‐TCF antagonists in clinical use.
Alice Melotti +5 more
doaj +1 more source